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We narrowed to 973 results for: ARC

Showing: 241 - 250 of 973 results
  1. The MTA at Addgene

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    Blog Post
    ...agreement that states the terms of use for a tangible research material that is shared between two parties. There... for organizations to make policy decisions on research use agreements. The UBMTA, which is the MTA most...well-understood and accepted by the majority of research institutes.  Pro tip! In most academic and nonprofit...Transfer department is responsible for managing research use agreements like MTAs.  Addgene does a lot ...plasmids at Addgene are shared under the UBMTA, researchers additionally have the option of distributing ...which allows the plasmids to be distributed for research use only to industry-based scientists. Some organizations...OpenMTA, which allows plasmids to be used for both research and commercial purposes. It’s important to note...
  2. Synthesized by Ginkgo Bioworks, Shared by Addgene: SARS-CoV-2 Plasmids for Many Expression Systems

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    Blog Post
    ... results helps other researchers using these plasmids and will give your research more visibility.    ...By Will Arnold and Shreya Vedantam Accelerating research by improving the availability of materials is ...to help academic and industrial labs accelerate research and to help find a faster solution to the COVID...coli and S. cerevisiae expression vectors in late March. The first set of 383 constructs went online just...samples, the rest will be put into a status we call “Archived.” This status allows us to store plasmids and ... is indeed global. Helping scientists speed up research is what we’re here for and we’re glad to be able...Ginkgo Bioworks  Find COVID-19 plasmids for your research Browse the Ginkgo Bioworks COVID-19 Plasmid Collection...
  3. Transferable Skills Guide: Problem Solving

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    Blog Post
    ...A 2017 survey found that many researchers feel they lack formal training in a variety of transferable...out to fill this gap by both highlighting that researchers do learn MANY transferable skills while working... into play while puzzling through your broader research questions and designing future experiments. Being...While I was in graduate school and beginning to research non-academic careers, I always felt that descriptions...when you’re faced with yet another hurdle in your research journey.  What are ‘problem solving skills’? As... about the world. You might do some background research to better understand it and come up with several... of your skill set later on. If you are new to research and the lab, you may not be able to carry out ...
  4. Working with Nuclear Receptors

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    Blog Post
    ...represents a unique funding model in nuclear receptor research, and has generated a set of comprehensive datasets... questions in nuclear receptor and coregulator research. Our Q-PCR datasets, for example, document the... today.  The sheer abundance of these critical research tools is a double-edged sword, however, and has...burden associated with identifying plasmids in the research literature and acquiring them in a timely manner...to the problem of sharing plasmids, providing researchers with a one-stop shop for plasmids and vectors...vectors, and making them available to all researchers for a reasonable fee. We at NURSA recognize the importance...importance of this service to the NR research community and, accordingly, the new version of the NURSA website...
  5. Sequencing Options for CRISPR Genotyping

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    Blog Post
    ...off-target cleavage events. Unbiased techniques search the whole genome for off-target sites irrespective... in concert, these approaches can provide the researcher with a reasonable level of certainly that the...sgRNA. This is a good starting point for most researchers as it provides a list of putative off-target ...can later sequence for mutations. One method a researcher can use to test predicted off-target sites following...to perform these validations as translational researchers begin to use CRISPR as a therapy. Low frequency... effects may generate irreproducible data in a research setting, but these events could have disastrous...off-target prediction algorithms, their genome-wide search criteria are not exhaustive. Mismatch tolerance...
  6. Corralling and Cornering the Goldilocks Antibody

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    Blog Post
    ... most commonly used research tools in scientists’ pockets. They allow researchers to identify and isolate...an antibody that will be essential to your new research project, but unsure which one will mark your target...bind to the target). Unreliable antibodies cause research that cannot be reproduced and projects that cannot... with collaborators and support from the Brain Research Through Advancing Innovative Neurotechnologies...Dr. Wu please contact us here! Ava Shipman is a research assistant in lab of Zhuhao Wu at the Icahn School...Reproducibility: Standardize antibodies used in research. Nature 518, 27–29 (2015). https://doi.org/10.1038...The Economics of Reproducibility in Preclinical Research. PLoS Biol 13(6): e1002165. https://doi.org/10.1371...
  7. High Complexity Golden Gate Assembly with NEB’s DAD

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    Blog Post
    ...on a stochastic search algorithm rather than pre-designed sets, so identical searches can return multiple...particularly for high-complexity reactions? The researchers over at New England Biolabs® thought otherwise...design (DAD) to build out three tools to help researchers design high-fidelity Golden Gate Assemblies and...three tools developed, outlined below, allow for researchers to select large sets (with overhangs that violate...You can define the number of fragments, and the “search windows” you’d like the tool to use to identify... can exclude specific sequences or set a narrow search window for a site—or sites—that must be used. Each...necessarily require cycling. The Pros and Cons Researchers used the tools above to complete a 52-piece assembly...
  8. 3D Printing Meets CRISPR Cas9

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    Blog Post
    ...students work closely with local researchers to learn about their research while creating physical models...graphics packages were soon developed that allowed researchers to create stunning, interactive images of their... only wonder what I am talking about. How do researchers use physical models of protein structure? We ...been creating physical models of proteins for researchers for the past fifteen years. On those occasions...following sequence of events plays itself out: The researcher breaks eye-contact with any other human in the... and to create custom models of proteins for researchers. Modeling CRISPR We were excited when Jacob Corn...strand. And this is why we love working with researchers on a model. The little knowledge that we have...
  9. Anatomy of a Plasmid Page at Addgene

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    Blog Post
    ...plasmid from our search page (check out this video for a walkthrough of the ways you can search our website...trail at the top of any plasmid page gives the hierarchy of web pages the plasmid page is nested in. You...website). A quicker way to find this plasmid through search is... The Addgene plasmid number: This is the unique...know the catalog number of the plasmid you are searching for, this is the quickest and easiest way to find...than 50; and blue, more than 100 times! When you search for plasmids on our website, one of the available...see if the plasmid would be useful for their own research, and helps requestors use the plasmid in their...citations for Addgene plasmids you have used in your research! Sequence information: Depositors may provide ...
  10. Cancer and the Immune System: Deciphering the Relationship

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    Blog Post
    ...longer than we’ve been studying it and, now, researchers are exploring ways to bolster and modulate our...protein blocking. Other molecular targets under research include TIM-3, LAG-3, STAT-3, EGFR, CD20 and CD73...to activate them are a few methodologies being researched. Apoptotic and necroptotic tumor cells have also...engineering have played a huge role. For instance, researchers are genetically altering tumor cells and immune... treatments enter the clinic, physicians and researchers are learning much about how treatment regimens... made more effective. Some important factors researchers are beginning to focus on include: Cell heterogeneity... important questions in this exciting field of research. One of the most important: How will cancers evolve...
Showing: 241 - 250 of 973 results