We narrowed to 973 results for: ARC

...actuator. In 2012, Adam Cohen's lab presented Archaerhodopsin 3 (Arch) as a new rhodopsin based voltage indicator...domain. Feng Zhang's group utilized the bi-lobed architecture of Cas9 to engineer a series of "split" cas9...Chao, Robert Singer, and Anne Ephrussi allows researchers to observe when and where translation occurs ...unprecedented activation of target genes A group of researchers headed by the Church Lab at the Wyss Institute... Peter Schultz and colleagues at the Scripps Research Institute have deposited a pair of plasmids for...potentials. The Cohen lab wished to improve on the Arch indicator and their collaborators in Robert Campbell...five rounds of random mutagenesis on a library of Arch mutants screening for improved brightness. The brightest...

...called “Teaching Your Research.” This course has participants take their research from the bench to the... level course based on their research interests. “So for me, I researched G-proteins at the time. This...program takes what you know about it [your area of research], and teaches you how to design a course, how ...off: “I spent about 6 months just editing and searching for a job and I stumbled upon eScience by luck...happenstance. It was on Indeed or one of the job search sites. It's  a rare trek these days to go in cold...

...including Addgene, positively affect scientific research. As Maria Castro of University of Michigan says... as the technology disseminates throughout the research community. These popular plasmids are categorized...distributed this year, serves to congratulate researchers who have at least one plasmid deposited at Addgene...generously shared their reagents freely with the research community. Sharing is caring We’re thrilled that...time for our depositors to continue conducting research. Said Blue Flame awardee Sophien Kamoun of the... we’re also proud to help connect scientific researchers from far corners of the world. “It’s easy to ...eliminate geographical restrictions in life science research." Claim Your Award If you have one or more blue...

... this position because I want to help make the research enterprise work better and because I really like...back on. While doing and presenting undergraduate research at BU, I realized that I’m energized by talking...difficulties behind great discoveries by tackling a research project and getting a PhD myself. To continue ...graduate student group, Science in the News. While research experience is key to my current position, I think...Kentucky where I spent a couple of days talking to researchers about their work, picking up plasmid deposits...ways Addgene can improve in its mission to make research easier. I’m hoping my story demonstrates that ...mine, that help support academia but the skills researchers gain doing PhDs (i.e. technical writing, teaching...

...fans of all forms of research sharing and with Open Data Day 2020 coming up on March 7th, what better way...resource. Instead of painstakingly searching for experimental details in research articles, scientists can use...experiments using a specific AAV tool. They can search the database by certain features like serotype,...the dedicated community of data-contributing researchers who use AAV tools. This word cloud (using...open data resource and accelerating reproducible research. Share your data on AAV data hub! Related resources...

...promote reproducibility, Addgene will have unique Research Resource Identifiers (RRIDs) for each antibody...connects colleagues and is invested in improving research infrastructure, from our educational materials...funded by a generous grant from the NIH’s Brain Research Through Advancing Innovative Neurotechnologies...continue to add more antibodies, for neuroscience research and other disciplines, over time. The resource...Resources As part of our commitment to supporting your research, Addgene is creating an array of educational materials... that you will find useful antibodies for your research. Please consider sharing your experiences with...Reproducibility: Standardize antibodies used in research. Nature 518:27–29. https://doi.org/10.1038/518027a...

...capable of at the same time. Barcoding libraries Just as physical barcodes help librarians track individual...individual books, genetic barcodes allow researchers to identify specific cells — as well as their descendants...sequencing the unique DNA barcodes. Figure 1: Schematic of barcoding with a pooled library. Created...from the Samantha Morris lab use a combinatorial barcoding approach to observe clonal dynamics and cell lineage...

...scientists have been coming to the Addgene website in search of plasmids. Now, scientists are beginning to see...classification This inquiry started when Neil Thompson, a research scientist at MIT’s Computer Science and Artificial... MIT labs in the Synthetic Biology Engineering Research Consortium. That is how Aditya Kunjapur, a MIT... gene sequences as natural or synthetic, the researchers looked at intrinsic properties (GC content or...85% correlates with synthetic sequences. The researchers then used their classifier to identify synthetic...lab-of-origin of engineered DNA This isn’t the only time researchers have used Addgene as a large data set. Alec A...Addgene.org Check out Addgene's synthetic biology page Search for a plasmid Find Addgene's most popular plasmids...

...year. While we love academic research, we hope we can help all researchers achieve happiness in their careers... on a diverse array of topics pertinent to the research community, two eBooks (Management for Scientists... science and the plasmids, technologies, and researchers behind them. As part of our thanks to you for...and CRISPR 101 series. These posts aim to give researchers the background they need to get started using... bring about the next revolution in biological research. We’re incredibly happy to see that one of our...deletions, and translocations. It also provides researchers with many different ways to control gene expression...

...localization. HiBiT-tagged targets in translational research Researchers can incorporate HiBiT with a wide range ...with knock-in models, ectopic models provide researchers with a means to quickly iterate, work across ...use of HiBiT provides a means to quickly answer research questions before creating knock-ins.  ... Cracking the code of 'undruggable' targets Researchers can design drugs to bind to well-defined ligand-binding...CRISPR knock-in HiBiT-tagged EGFR cells allowed researchers to track endogenous activity of EGFR, including...advances detection of endogenous proteins As researchers continue to improve more physiologically and ...the heterogeneity and spread of hepatocellular carcinoma in human tissue and in vitro. Oncology Reports...