We narrowed to 724 results for: ACE

1. DAP arrays for multiplex gene editing

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   Blog Post

   ...array encoding the tandemly assembled tRNA-gRNAs is placed downstream of a lengthy promoter, which is used...

2. Using CRISPR/Cas9 to Edit Disease Out of the Genome

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   ...Application in Genetic Diseases: A Review.” Current pharmaceutical biotechnology. https://doi.org/10.2174/1389201021666200621161610...

3. New Neuroscience Tool: The iGluSnFR3 Glutamate Sensor

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   ...sensor to the membrane and displays it on the extracellular side. In addition to the original PDGFR TMD,...

4. Scientists Map the SARS-CoV-2-Human Interaction Network

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   ...Twitter (QBI_UCSF and KroganLab), Instagram, and Facebook. Find more COVID-19 and coronavirus related plasmids...

5. The Crispr Babies Saga Shows the Need for Action, Not More Delays

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   ...established ethical issues raised around mitochondrial replacement therapies. In other words, rather than having...

6. Plasmids 101: NGS Quality Control for Pooled Libraries

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   ...commonly uses a custom script derived from the count_spacers.py file from Feng Zhang’s laboratory. There are...

7. Four Factors that Differentiate the Stem Cell Field

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   ...communities, but usually I only get to scratch the surface of different fields. This meeting has given me ...

8. Addgene Welcomes John Doench to the Advisory Board

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   ... need to spend time here, this is an incredible place.” Doench has spent most of his research career working...

9. Advice for Scientists Starting a Lab

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   ... who was always “off flying his plane to exotic places while occasionally emailing us his worldly advice...

10. Plasmids 101: Inducible Promoters

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    ...and allowing reporter gene transcription to take place. Addgene also has popular light-regulated two component...

11. Quick Guide to Working with Drosophila Part 3: Genome Engineering in Flies

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    ...process is fairly straightforward. Basically, you place your gene of interest in a plasmid and get the vector...

12. Cancer, Inflammation and Immunity - Harnessing the Body’s Defenses to Fight Cancer

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    ...the upregulation of the immunosuppressive cell surface receptor PD-1. This immunosuppressive environment...

13. Enabling Precision Functional Genomics with the Target Accelerator Plasmid Collection

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    ...Learn About our Cancer Colleciton Pages Use the ClonTracer Library for Lineage Tracing Learn About Cancer...

14. Multiplex Genome Editing with CRISPR-Cpf1

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    ...Usually Destroyed Yes, Cpf1 cleaves 5' of the protospacer Multiplexing CRISPR-Cas9 options before Cpf1...

15. Addgene’s Viral Service - Why Virus? Why Now?

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    ...will help scientists Good science isn’t the only facet of a project this big. Maintaining our excellent...

16. Choosing a CRISPR Nuclease: Site Accessibility, Specificity, and Sensitivity

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    ...Engineered CRISPR-Cas9 nuclease with expanded targeting space." Science 361.6408 (2018): 1259-1262. PubMed PMID...

17. Plasmids 101: Transformation, Transduction, Bacterial Conjugation, and Transfection

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    ...nature, this genetic material often comes from adjacent lysed bacteria and can include plasmid DNA or ...

18. Hot Plasmids - June 2019 - Optogenetics, Acoustic Reporter Genes, microRNAs, and the CRISPR-Cas9 system CHIME

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    ...sometimes require an alternative such as a radioactive tracer. As a solution, Mikhail Shapiro’s lab has developed...

19. Q&A with Karen Katz and Carl Paratore, the Newest Members of the Addgene Board of Directors

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    ...making sure we have adequate process and controls in place to manage those scenarios. What is the best piece...

20. Viral Vectors 101: Types of viruses

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    ...are roomy: some adenoviruses pack up to ~35 kb of space for cargo! Adenovirus is an effective option if ...