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We narrowed to 969 results for: ARC;

Showing: 281 - 290 of 969 results
  1. Isolating Genomic Regions of Interest with the CRISPR System

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    Blog Post
    ...While much of CRISPR research has focused on genome editing, numerous discoveries have been made using...But dCas9 does not cleave the DNA. Much of the research using dCas9 has focused on transcriptional activation...antibody targeting the 3xFLAG tag, allowed these researchers to isolate dCas9 with the bound genomic locus...flavors to this methodology. Using this technique, researchers have begun to make important discoveries in various... region, other forms of enChIP, and additional research conducted in the Hodaka Fujii Laboratory, please...enChIP) using CRISPR." Biochemical and biophysical research communications 439.1 (2013): 132-136. PubMed PMID...the analysis of bacterial genome functions." BMC research notes 11.1 (2018): 387. PubMed PMID: 29898790....
  2. "Hall of Fame" AAV Enhancers from the Allen Institute for Brain Science

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    Blog Post
    ... applied to research. Sharing knowledge and tools is the best way to help propel research forward and ...greater outcomes together. The Allen Institute is a research organization that is committed to understanding...life and health and works to advance foundational research. There are many focus areas of the Allen Institute...outside of the enhancers and their neuroscience research. This includes other data, tools, and resources...Institute contributes to. Enhancing science How research is conceived, developed, funded, and shared has...improved, reliable tools to help carry out that research. Organizations like the Allen Institute are committed...
  3. Twenty Years of Sharing: Expanding Accessibility

    Type
    Blog Post
    ...a little over half of our orders coming from researchers outside the USA, having some materials available...data and resources to increase accessibility to researchers around the globe. Addgene’s educational resources...become our collection pages. These pages allowed researchers to easily access and compare their options for...expression types, and more, all of which help a researcher understand if a material is right for their experiment...2023, we had over 900 posts, which were read by researchers all over the world — and we really do mean all...educational resources’ value is feedback from the researchers who use them. The best part of any conference...crowdsourcing experimental help. We love it when a researcher reaches out to ask if they can help us create...
  4. Healthcare Consulting: A Door to the Business of Life Sciences

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    Blog Post
    ...depending on the part of the company involved: Research & Development (R&D) teams at pharma companies ...companies carry out preclinical and clinical research to discover and test the best new therapeutics. Consultants...among physicians and scientists about clinical research, drugs, the diseases they can treat, and diagnostic...client might need to get a large amount of market research done to inform a go/no-go decision in a very short...PhD, an MD, or someone trained in any aspect of research in biology or medicine you will bring an essential...global health organizations, investment and equity research firms, biotech start-ups, venture capital firms...consultants. I have even seen consultants go back to research and bench science, with a newfound appreciation...
  5. 2022 and 2023: Reflections and Looking Forward

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    Blog Post
    ...to share curated information about AAV usage in research applications. Scientists around the world can ...Reports receive a DOI for citation, crediting researchers when their data is used by the community to drive...in materials sharing, information sharing, and research reproducibility while expanding our suite of materials... materials and services to support more research and innovation around the world. As always, we seek to...opening up science to help create new knowledge and research opportunities. I have spent the last 9 months ...same is Addgene’s commitment to supporting the research community through sharing science and distributing...
  6. Antibodies 101: Introduction to Immunofluorescence

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    Blog Post
    ...within a cell,” “Does this disease change the architecture of my cells,” or “How does this mutation impact...about IF, direct and indirect. For direct IF, researchers use a single antibody to visualize their target...their results and corresponding protocols. Other researchers may also have tested an antibody in IF and will...organism that is underrepresented in the biomedical research community. You may have to take some risks on ...provide you not only answers to your most pressing research questions, but also stunning images (am I the ...results as artwork at home?). Take your time to research antibodies, protocols, and appropriate controls...Additional Resources on the Addgene blog Learn about research applications of antibodies in Introduction to ...
  7. Viral Vectors 101: Integrase-Deficient Lentiviral Vectors

    Type
    Blog Post
    ...over three decades. Widely used across various research applications, they have become indispensable tools...and organisms. They can be used for a variety of research purposes, like creating stable cell lines, delivering...vectors work with regards to integration, and how researchers have modified them to prevent this integration... DNA… forever!  This can be an advantage for researchers looking to generate long-lasting changes in cells...genome (Figure 1). IDLVs were first discovered by researchers investigating HIV integrase mutants in the early... choice for certain types of clinical or basic research applications. Considerations for IDLV use If you...you know how IDLVs could be useful in your own research, we wish you the best of luck with any experiments...
  8. Five Popular Model Organisms

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    Blog Post
    ...Morgan Model organisms are vital tools used by researchers around the globe. These organisms share many ...most preferred mammalian model organism of many researchers: the mouse (Mus musculus). Mice have many advantages... human diseases and have successfully helped researchers develop a variety of therapies. For example, ...fly. The fruit fly has been used in scientific research for over a century but was brought to the forefront...Morgan, who is known as the “father” of Drosophila research. Morgan discovered that genes were found within...is a commonly used model organism in scientific research. Yes, the same kind we use in breads and other...molecular biology reference Find plasmids for your research ...
  9. Targeting HIV-1 with CRISPR: Shock and Kill or Cut it Out?

    Type
    Blog Post
    ...latently infected cells. To truly cure HIV-1, researchers need to vanquish these hidden viral reservoirs...“shock and kill” the HIV-infected reservoir, researchers have previously used histone deacetylase (HDAC...could permit some viral protein production, so researchers are also interested in precisely excising the... were used for proof-of-concept studies, but researchers believe that using CRISPR/Cas9 could improve ...represent exciting advances in preclinical HIV-1 research that should be pursued in animal models, and it...benefit many others and accelerate the pace of research. We at Addgene hope to see the problem of in vivo...updated CRISPR Guide! Find CRISPR Plasmids for Your Research Browse gRNA Design Tools  ...
  10. Reflections and Looking Ahead

    Type
    Blog Post
    ... discovery. Over 150,000 plasmids empowering researchers worldwide. Countless breakthroughs enabled by...characterized antibodies, and our contributions to key research papers are already inspiring higher standards ...as DNA or bacterial stabs — ‌and reinventing our search experience so you can find exactly what you need... evolving rapidly, and with it, the needs of researchers worldwide. Through our growing community on Bluesky...incredible journey. Together, we're not just sharing research materials — we're accelerating the future of science...critical to enhance reproducibility in biomedical research. eLife, 13, e100211. https://doi.org/10.7554/eLife...
Showing: 281 - 290 of 969 results