Starter Guide to induced Pluripotent Stem Cells (iPSCs) Part 2: Reprogramming and Transdifferentiation
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Blog Post
...β-like-cells [37, 38].
In 1987, Davis et al. reported one of the earliest examples of transdifferentiation...from fibroblasts, human keratinocytes from hair pluck, peripheral blood cells, and renal epithelial cells... damage results in the transdifferentiation of glucagon-producing α-cells into insulin-producing β-like-cells...Dedifferentiation, transdifferentiation and reprogramming: three routes to regeneration. Nat Rev Mol Cell Biol, 2011...