We narrowed to 132 results for: atm

1. No Llamas Required - Synthetic Nanobodies Against Membrane Proteins

   Type

   Blog Post

   ...lot of press for being a promising approach for treatment or prophylaxis of COVID-19. Researchers identified...research, this protocol holds promise for developing treatments for other diseases or for studying other membrane-bound...

2. Uncovering Ancestral Bias in CRISPR Research

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   Blog Post

   ...Cancer Dependency Map cancer cell lines (left). Heatmap indicating the breakdown of ancestry associated...Cas machinery where to cut.      Fig. 2: Heatmap indicating loci where SNPs reside on sgRNA target...

3. Deep Dive: Fixing and Permeabilizing for Immunofluorescence

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   Blog Post

   ...fix and permeabilize in one step, then methanol treatment could be an effective strategy. (This article ... Chen JW, et al (1985) Postfixation detergent treatment for immunofluorescence suppresses localization...

4. Deciphering the Mysteries of Behavior with Viral Vectors

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   Blog Post

   ... 1970s to test the efficacy of antidepressant treatment in rodents. In this test, an animal is placed ...deep brain stimulation to emulate optogenetic treatment of synaptic pathology." Science 347.6222 (2015...

5. Targeting HIV-1 with CRISPR: Shock and Kill or Cut it Out?

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   Blog Post

   ... viral levels will soon skyrocket back to pre-treatment levels due to the viral reservoirs located in ...cell lines, as well as a latent microglial line, treatment with CRISPR/Cas9 SAM increased the percentage ...

6. Deep Dive: Statistical Tests (Comparisons)

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   Blog Post

   ...same subject or population - before and after a treatment, for example - should be analyzed with a paired...arising from different subjects or populations (a treatment group vs. a control group), on the other hand,...

7. Fluorescent Protein Guide: Biosensors

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   Collection

   ...Glutamate Membrane displayed variants of fluorescent glutatmate sensors (iGluSnFR1) Genetically Encoded Glutamate...

8. With an Eye Towards the Future, We Look Back at the March for Science

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   Blog Post

   ...into a successful PhD thesis. We use the same atmospheric physics to understand exoplanets that we use ...organized the march was, as well as the friendly atmosphere that was created by the many thousands of science...

9. Tips for Working in Industry & Success in Management: Interview with Crystal Shih

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   Blog Post

   ...BioMedical Research to develop novel biologics for the treatment of various diseases, from heart failure to Alzheimer...

10. Plasmid Grant to Aid Cervical Cancer Screening in Ghana

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    Blog Post

    ...allowing for early cervical cancer detection, treatment, and management. We are incredibly happy to hear...

11. How Exercise Purges Stress and Keeps Depression at Bay

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    Blog Post

    ...they write. “In the future, these may lead to treatments for a variety of brain disorders, including psychiatric...

12. A new platform for fast functional characterization of potentially cancerous mutations

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    Blog Post

    ... furthering research and developing effective treatments for the disease. Recently, Kenneth Scott’s lab...

13. Seeing Red: Simple GFP Photoconversion

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    Blog Post

    ...labs made the accidental discovery that laser treatment can photoconvert GFP from green to RED! This simple...

14. Scientific Sharing in the Time of COVID-19: Databases and Resources

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    Blog Post

    ... hopefully help guide policies and ultimately treatments in a timely fashion.”  With this in mind, Bourque...

15. Same Addgene, New Look - Why We Redesigned Our Homepage & Mascot

    Type

    Blog Post

    ...realized that Blugene needed the same thoughtful treatment. Blugene has been with us since 2011, and while...

16. New Norepinephrine Indicators: nLightG and nLightR

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    Blog Post

    ... NE (10 μM) and corresponding pixel-wise ΔF/F0 heatmaps. White insets indicate surface expression of the...

17. Supporting Rare Disease Research with BeHeard 2017

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    Blog Post

    ...mesothelioma, there are currently no targeted treatments for peritoneal mesothelioma. Dr. Nabavi and colleagues...

18. SpyLigase Irreversibly Locks Peptides Together for Efficient Cell Capture

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    Blog Post

    ...to have a big impact on our understanding and treatment of cancer. It is clear that one needs to capture...

19. 28 Hot Plasmid Technologies from 2015

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    Blog Post

    ...rapamycin-inducible Cas9 for genome editing. Without rapamycin treatment, the Cas9(N)-FRB-NES fragment is actively shuttled...the nucleus due to the nuclear export sequence. Treatment with rapamycin induces Cas9(N)-FRB-NES and Cas9...

20. The Open Repository of CRISPR Screens: CRISPR Screen Data in One Place

    Type

    Blog Post

    ...interested in a particular disease, cell type or drug treatment can browse through screens performed in relevant...