Gamma-Retroviral Vector Guide
Type
Guide
...Figure 2): Transfer plasmid — contains transgene, sgRNA, or shRNA of interest flanked by LTRs; ~8 kb packaging...plasmids, as lentiviral vectors do. For more about lentiviruses, see Addgene's lentiviral vector guide...available at Addgene. Gamma-Retrovirus Versus Lentivirus Lentiviruses and gamma-retroviruses fall under the Retroviridae...main difference between lentiviruses and gamma-retroviruses is that lentiviruses are capable of infecting...that lentiviruses can infect a greater variety of cell types than retroviruses. Both lentiviruses and ...containing only the necessary packaging genes, while lentiviruses also contain accessory genes specific to each...gamma-retroviruses may not be efficiently packaged by lentiviral packaging systems, and vice versa. Gamma-retroviral...