We narrowed to 810 results for: mal

1. Using CRISPR/Cas9 to Edit Disease Out of the Genome

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   ...that CRISPR/Cas9 could be used to edit several autosomal-dominant mutations that have been connected to...

2. 5 Great Apps for Lab Life

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   ... Lastly, the Tm calculator helps you set up an optimal PCR depending on the primer sequence and the NEB...

3. R Bodies: Membrane-Rupturing Microscopic Tools

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   ...to find R body mutants that couldn’t extend at a normal pH and later realized that these mutations clustered...

4. From Lab Bench to Leadership: Transitioning into Management as a PhD

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   ...to my mentors, as they encouraged me to explore small-scale opportunities where I could make mistakes ...

5. Flow Cytometry Readouts: Yes, No, and Everything in Between

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   ...still continue gating populations of interest with normal gates, just based on a histogram plot instead of...

6. Clear and Accessible Writing

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   ...accessible to even more people.  Whether you start small with alt text or immediately dive into applying ...

7. Viral Vectors 101: Viral Vector Elements

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   ...viral vectors Of the many viruses out there, only a small subset are commonly used as tools in the lab. We...

8. GCE4All: Making Genetic Code Expansion Accessible

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   ...paper was published, followed soon by GCE done in mammalian cells (Shandell et al., 2021).   How it works...

9. Viral Vectors 101: Viral Applications

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   ... A Versatile Viral tool for Gene Expression in Mammals Listen to Connie Cepko Discuss Gene Therapy with...

10. New and Upcoming Viral Vectors - May 2020

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    ...experiments. To this end, we offer control AAV in smaller aliquots of 20ul for serotype testing to help you...

11. The Many Reasons for Irreproducible Research- and a Vaccine to Eradicate It

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    ... the problems above: unclear methods, QRPs, and small samples, then when replications do not come out ...

12. Behind the scenes: Addgene’s new search engine and more

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    ...and serotype, among others. We also created a normalization mechanism to “collapse” variations and synonyms...

13. Opto-Nanobodies: Using Light to Manipulate Cell Signaling and Protein Purification

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    ...light is in an open conformation.  Nanobodies are a small (~15 kDa), single monomeric variable heavy chain...

14. A Novice's Perspective on Neuroscience - SfN2017

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    ...delivering genes to many different cell types with minimal immunological effects. AAVs are used in experiments...

15. Addgene’s Viral Service - Why Virus? Why Now?

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    ...the middle of 2016 Addgene started distributing a small but growing catalog of ready-made AAV and Lentiviral...

16. Q&A with Karen Katz and Carl Paratore, the Newest Members of the Addgene Board of Directors

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    ...Businesswomen’s Association. We were involved in smaller group activities through the HBA and I got to know...

17. Hot Plasmids - June 2019 - Optogenetics, Acoustic Reporter Genes, microRNAs, and the CRISPR-Cas9 system CHIME

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    ... genes for noninvasive imaging of microbes in mammalian hosts Article contributed by Lukas Morgan  Listen...

18. Quick Guide to Working with Drosophila Part 3: Genome Engineering in Flies

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    ...your docking site is located). This amounts to a small difference of two or three weeks. 3. How would you...

19. Cancer, Inflammation and Immunity - Harnessing the Body’s Defenses to Fight Cancer

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    ...starvation on cancer therapy. Findings in previous animal studies suggested that fasting has a positive effect...

20. Multiplex Genome Editing with CRISPR-Cpf1

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    ...bulk from crRNA expression plasmids resulting in smaller, more streamlined vectors which are easier to use...