We narrowed to 810 results for: mal

... also false negatives: These are rare, but if a small fragment is inserted in-frame, read-through can ...

... could typically achieve 90-99% knockdown with minimal off-target effects. The system also enabled them...

...one can introduce changes into the genomes of mammalian or other cells. TALENs are engineered proteins...

...quantified for individual cells, and the number of 'normal' looking cells can be counted. This assay will ...

...should enable researchers to make precise edits in mammalian cells and may decrease worries about off target...

...further away. While constitutive promoters drove maximal gene expression near genomic origins of replication...

...to use or build on work done previously, borrow small aliquots of restriction enzymes for one-off projects...

... faster presentation with more information than normal. I had to learn to observe and adjust on the fly...

...better resolution as these immune complexes are smaller than a primary:secondaries:conjugates complex. ...

...survey found that many researchers feel they lack formal training in a variety of transferable skills. At...

...pooled library of mutant sensors expressed in a mammalian cell line engineered to be electrically excitable...

...great gene therapy delivery mechanism, but their small packaging capacity of 4-5 kb limits the delivery...

...” “material,” “item,” and “format” all received formal definitions in our lexicon. We created documents...

...expression of ion channels, despite having an otherwise normal genomic background, can even lead to the formation...

...increased number of fragments, or the ligation of very small/very large fragments, these problems can be overcome...

...references and sorting out what they mean is no small task. As a scientist, it is useful to make literature...

...parts delivered) in certain model organisms. In mammals, most CRISPR libraries are assembled and delivered...

...originally written, the main focus was on editing animal models of disease and cultured cells. For example...

...from viruses that can infect people, cells, and animals. Some of these viruses are completely inert, but...

...intervention that rescues the function of even a small fraction of Arg-mutant proteins could improve health...