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We narrowed to 973 results for: ARC

Showing: 381 - 390 of 973 results
  1. Plasmids 101: Repressible Promoters

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    Blog Post
    ...the complexity of the system, researchers have used split GAL4 architecture or combined the system with ... ON state, and how you might use these in your research. Today, we’ll look at repressible promoters, which...bind the promoter and repress pADH1 activity. Researchers have engineered pADH1 variants that are less ...(2006). https://doi.org/10.1186/1472-6750-6-43Kaczmarczyk A, Vorholt JA, Francez-Charlot A. Cumate-inducible...
  2. CRISPR 101: Epigenetics and Editing the Epigenome

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    Blog Post
    ...expression or silencing. To alter DNA modifications, researchers used blunt tools like histone deacetylases, but...epigenetic modifications at a user-specified locus. Researchers showed that TALE-TET1 constructs, which fused...transcription at CpG regions of various promoters. Other researchers additionally fused a TAL effector to LSD1 histone...and dCas9-based epigenome editing. Nucleic Acids Research 47:e23–e23. https://doi.org/10.1093/nar/gky1286...system for targeted DNA methylation. Nucleic Acids Research 44:5615–5628 . https://doi.org/10.1093/nar/gkw159...
  3. Is this the right place for me? 8 tactics for choosing a lab

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    Blog Post
    ... lab website, publication records, LinkedIn, ResearchGate or Twitter. Be ready for the interview with ...with the rise of movements such as the Future of Research Symposium and #MeTooSTEM, academic bullies are...first place. This is another reason to do your research and choose wisely. From the Tenure She Wrote blog...undermining personal integrity, destructive innuendo and sarcasm, persistent teasing, name calling, insults, intimidation... to consider less expensive, portable areas of research (transgenic mice—out, zebra fish—in) Team attitude...
  4. PiggyBac-ing Through the Genome Editing Field

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    Blog Post
    ... selection marker such as thymidine kinase, a researcher may subsequently kill off any cells that still...later restores the target sequence. This allows researchers to avoid making unnecessary base pair changes...powerful technology that may be used for a variety of research applications, including making transgenic cell...molecular and cellular biology and brings 10 years of research experience with stem cells to Transposagen's cell...Mathew applies his specialized knowledge to help researchers identify the right technologies and strategies...
  5. Introducing Addgene's Microbiology Pages

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    Blog Post
    ...on the right-hand side of the search page to narrow your keyword search to one of these organisms. Help...plasmid kits and other resources for microbial research. Kits, guides, plasmids, and more We have Plasmid...resources that we created filters just for them on our search page. Use the Expression and Insert Species filters...
  6. Addgene’s Blog Gets a New Look!

    Type
    Blog Post
    ...you’re new to the topic. Or, try the search bar Now, you can search for the articles you want to find without...on the search bar at the top of the screen and type in what you’re looking for. After you search, you’ll...
  7. Celebrating One Million Plasmids Shared!

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    Blog Post
    ... us to calculate how much time we have saved researchers. In a recent blog post, we looked at how long... plasmid and how much time Addgene has saved researchers. Assuming 5 hours of hands-on time to make each...are always on the lookout for new ways to help researchers facilitate and accelerate scientific discovery...discovery. How can Addgene help accelerate your research? Let us know! ...
  8. Plasmid Grant to Aid Cervical Cancer Screening in Ghana

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    Blog Post
    ...continuation of our efforts to provide resources to researchers in developing countries or that work in under-funded...continued opportunity to get plasmids to the researchers who need them the most. Check back here to learn...more about future awardees and their inspiring research. Additional Resources on the Addgene Blog Learn...Resources Learn About Our Grants to Rare Disease Research Resources on Addgene.org Check out our Cancer...
  9. Antibodies 101: Validation

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    Blog Post
    ...important. Antibodies are a critical component of the researcher toolkit due to their ability to bind to molecular...culprits in the reproducibility crisis of biomedical research (Baker, 2015; Bradbury & Plükthorn, 2015).  To...which represent five experimental strategies researchers can use to show that their antibody performs ...Reproducibility: Standardize antibodies used in research. Nature 518:27–9. https://doi.org/10.1038/518027a...finding and validating suitable antibodies for research. Mabs 8:27–36. https://doi.org/10.1080/19420862.2015.1100787...
Showing: 381 - 390 of 973 results