We narrowed to 275 results for: mel

1. An Addgene Co-op: The Intersection of Fun, Friendship, and Work

   Type

   Blog Post

   ...at one of my first “All Addgene” meetings, when Melina, our CSO and co-founder, approached me and asked... time for me to present, I thought I would be extremely nervous (I mean I WAS presenting to three department...

2. Safe Port in a Storm...How Addgene is Weathering the Pandemic

   Type

   Blog Post

   ... with 80% of the team working remotely. We’re extremely proud of the work we’ve done to support COVID-...the spring and early summer months. We are also extremely grateful to the grant officers at Fast Grants....

3. Hot Plasmids June 2018 - Reverse transcriptase, nanobody, and protein-DNA interaction tools

   Type

   Blog Post

   ...regard and is even able to reverse transcribe the extremely long, highly structured HCV genome (~9.6 kb of...engineered from heavy-chain only antibodies found in camelids. They possess many advantages over conventional...

4. Improving Transduction Efficiency with Exosome AAVs

   Type

   Blog Post

   ...IX in liver in a mouse model of Haemophilia B (Meliani et al., 2017). Exo-AAV9 was successfully shown ...PMID: 22314290. PubMed Central PMCID: PMC3345986. Meliani, Amine, et al. "Enhanced liver gene transfer and...

5. Addgene-Seeding Labs plasmid grant round 3: microbial drug resistance and biofilms, antidiabetic plant components, visualizing brain injury - and a glowing robot fish

   Type

   Blog Post

   ...compounds with antidiabetic properties that can ameliorate diabetics nephropathy, one of the major pathophysiological...pathophysiological complications of diabetes mellitus. Recombinant human proteins that play a role in insulin...

6. Creating accessible biology activities in schools with BioBits

   Type

   Blog Post

   ...certain chemicals into fragrances that they can smell, or enzymes that can create hydrogels that they ...textbooks with real world results that they can see, smell, and touch. Along the way, we hope they’ll also ...

7. Learning Technical Skills at a Lab Central Workshop

   Type

   Blog Post

   ...who was working with cell culture and who was extremely helpful since she was familiar with library generation...resource for the research community, so it is extremely important for us as a company to constantly update...

8. Predicting Adverse Reactions to Monoclonal Antibody Drugs

   Type

   Blog Post

   ...From Manufacturing to Preclinical Studies. In J. Bluemel, S. Korte, E. Schenck, & G. F. Weinbauer (Eds.)...doi.org/10.1016/B978-0-12-417144-2.00027-5van Brummelen, E. M., Ros, W., Wolbink, G., Beijnen, J. H., ...

9. R Bodies: Membrane-Rupturing Microscopic Tools

   Type

   Blog Post

   ...Jessica Polka, a Postdoctoral Research Fellow with Pamela Silver.  Most types of biological motion (whether...Jessica Polka is a Postdoctoral Research Fellow with Pamela Silver in the department of Systems Biology at ...

10. Developing a cold tolerant E. coli using specialized chaperones

    Type

    Blog Post

    ... corrosive pH ranges, crushing pressures, near-melting temperatures, tons of radiation, or freezing cold...operational time for a given process. These are extremely useful benefits for any food processing industry...

11. Viral Vectors 101: Viral Applications

    Type

    Blog Post

    ...in the limelight. The FDA approved the first oncolytic viral therapy in 2015 to treat melanoma, and many...

12. Addgene: The First Twenty Years

    Type

    Blog Post

    ...websites, Facebook and Gmail, were launched. And Melina Fan, a cell biology graduate student, was frustrated... A blast from the past: Cofounder and CSO Melina Fan setting up Addgene's very first in-house NGS...

13. Working with Nuclear Receptors

    Type

    Blog Post

    ...be required by one or more NRs for efficient and timely activation or repression of gene expression (see...the research literature and acquiring them in a timely manner. Addgene represents an excellent solution...

14. Viral Vectors 101: Calcium Sensors

    Type

    Blog Post

    ...mitochondria), the Cameleon-based FRET sensor D1ER, and GCaMPER. Bonus: There are also Cameleon-based FRET sensors...

15. Adapting Toehold Switches to Detect Zika Virus

    Type

    Blog Post

    ...publication timeline I think we can speak for all the authors on the paper when we say the timeline to develop...

16. Reaching out to China: Canton Nucleic Acids Forum (CNAF) 2015

    Type

    Blog Post

    ...by Nobel Laureate (and Addgene depositor) Craig Mello. Taking his groundbreaking work in RNAi one step...involved in preventing silencing of self-genes. Dr. Mello presented a hypothesis that these pathways are involved...

17. Mobile-CRISPRi: Bringing CRISPRi to Diverse Bacteria

    Type

    Blog Post

    ...plasmids, and lack the ability to synthesize diaminopimelic acid (DAP), a component of the cell wall. Once...Central PMCID: PMC5180612. Libby, Elizabeth A., and Pamela A. Silver. "Harnessing undomesticated life." Nature...

18. Polymerase Chain Reaction Overview and Applications

    Type

    Blog Post

    ...molecular cloning, sequencing, and genotyping. It’s extremely useful but is not as quantitative as other methods...multiple primers all in one PCR reaction. This is an extremely useful PCR method that can help save time and ...

19. Experimenting with New Careers while in Grad School

    Type

    Blog Post

    ...This post was contributed by guest blogger Melanie Fox, founder and executive director of Central Indiana...fully take advantage of my graduate experience. Melanie Fox is currently the founder and executive director...

20. SciComm: Taking Science to Elementary and Middle Schools

    Type

    Blog Post

    ...does, and how one becomes a scientist. I gave a timeline of my science life, starting back to Mr. Kelley...engaging examples of how understanding genetics is so timely.” Genome engineering, and many other technologies...