We narrowed to 988 results for: Ran

1. BeHeard Award 2018: Diseases of Glycosylation, Arginine Mutagenesis, & Neural Development

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   ... the Rare Genomics Institute to provide plasmid grants to researchers working on rare diseases through...the glycan biosynthetic pathway and have a wide range of clinical manifestations. PMM2-CDG is the most...

2. Progress Towards a PAM-Free CRISPR

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   .... The activity of SpRY was validated in double stranded cleavage and base editing applications, with high...solution? Almost! Assuming a PAM of NRN, 50% of randomly selected genomic loci will have a PAM located ...

3. Viral Vectors 101: Chemogenetics

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   ...approved drugs so that your results are viable for translation to human patients. Picking receptors The receptor... specifically designed Gi-coupled receptor in transgenic mice. Nature Biotechnology 17:165–169 . https...

4. Early Career Researcher Toolbox: Finding Relevant Papers

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   ...research or larger journals that publish about a broad range of topics.  Twitter paper bots: Twitter bots tweet...you expand your search. Results in your feed are ranked based on their influence on the network, or body...

5. CRISPR in the Clinic

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   ...CRISPR targets — Sickle Cell Disease (SCD) and Transfusion-dependent beta thalassemia (TBT), both of which...clinical trial for SCD in 2022 as well. Hereditary transthyretin amyloidosis (hATTR) hATTR is caused by a variety...

6. Adapting Toehold Switches to Detect Zika Virus

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   ...fast-tracked development of diagnostics. Mostly transmitted by Aedes mosquitoes (aegypti and albopictus) ...and electronic companion technologies that has transformed the assay’s capabilities. Specifically this includes...

7. The Materials Science of Optogenetics Experiments

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   ...tissue, placement above the site of stimulation guarantees that the majority of the opsins will receive ...tangled. Furthermore, to give the animal the full range of motion, a commutator allows the patch cable to...

8. Gaining Leadership Skills Volunteering at a Professional Organization

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   ...national issues. I applied and was successfully granted a travel award to attend the annual NPA meeting...to think about their career options, gaining transferable skills such as leadership skills can only assist...

9. Experimenting in an Open Source lab: from CRISPR to Cats

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   ...month - with only occasional supplementation with grant funds, money is always tight. Of course, unlike ...becomes obsolete amazingly fast, but with a wide range of skills among our members we’ve managed to learn...

10. Quick Guide to Working with Drosophila Part 1: Getting Started with Flies

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    ...other words, newborn poop) visible through their translucent bodies. This is the ideal stage to select for... transgenic flies...

11. Plasmids 101: Degron Tags

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    ...of an exogenous small molecule). Degron tags can range in size from several kDas up to ~35 kDa and are ... because the system modulates protein post-translationally, unlike many other methods. Secondly, these...

12. Addgene's Cancer Collection Pages Connect the Research Community

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    ...’s group at the University of California, San Francisco, is approaching the Ras problem by exploiting ...lines. Further, for each plasmid in the kit, the transcript most commonly found across all TCGA tumor samples...

13. Anatomy of a Plasmid Page at Addgene

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    ... end up on the N or C terminus of the transcribed and translated insert. If it is an empty vector with...

14. SciComm: Taking Science to Elementary and Middle Schools

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    ...olds in a single evening. Grades K-5 cover a broad range of attention spans, skill levels, and STEM exposure...aspects of talking to 8th graders was the broad range of questions I received. I gave my presentation ...

15. Introducing Addgene's New Search - Find Plasmids More Easily For Your Research!

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    ...for details). The following screenshots show the range of different terms we can use to find materials ...exact plasmid you need. The ability to apply a wide range of filters isn’t new to Addgene’s plasmid search...

16. Plasmids 101: Protein tags

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    ...usually smallish peptides incorporated into a translated protein. As depicted in the accompanying cartoon...peptide-based proteosome inhibitors, glutathione S-transferase (GST), which can be fused to recombinant proteins...

17. Mesothelioma - Causes, Symptoms, and Treatment

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    ...of diagnosis) is about 35 years, but it usually ranges from 20-50 years and sometimes longer. There is...be Used to Study Cancer Drug Resistance Plasmid Grant to Aid Cervical Cancer Screening in Ghana Additional...

18. Tips for Writing a Good Cover Letter

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    ...can use your cover letter to explain why your transferable skills make you a good candidate for the position...experience or skills, often by pointing to your transferable skills. In the above example, if you don’t have...

19. 5 Reasons to Use Reddit for Science Communication

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    ... general advice on how to meet people, how to transition out of academia, and other science career topics.... Although I didn’t start answering until 5pm, frankly, I was typing far before five. Fortunately I have...

20. The Challenges of Cell Culture

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    ...cell line contamination: Epithelial Mesenchymal Transition Is Required for Acquisition of Anoikis Resistance... to carry our independent quality control for a range of testing, from animal doping to forensics, DNA...