We narrowed to 935 results for: INA

1. Components of CRISPR/Cas9

   Type

   Blog Post

   ... variants have two endonuclease domains: the n-terminal RuvC-like nuclease domain and the HNH-like nuclease...

2. Predicting Adverse Reactions to Monoclonal Antibody Drugs

   Type

   Blog Post

   ...triggering a humoral immune response. ADAs can inactivate the drug and increase drug clearance, lowering...

3. Trading Spaces - Visiting Scientist Edition

   Type

   Blog Post

   ...equipment that is custom-built, hard to find, or inaccessible to you for another reason. Visiting would allow...

4. The MTA at Addgene

   Type

   Blog Post

   ...office when materials are requested, instead of coordinating signatures from two different institutes. Our...

5. Plasmids 101: NGS Quality Control for Pooled Libraries

   Type

   Blog Post

   ... preferentially, skewing the composition of the final recovered DNA. This bias can be counteracted by ...

6. Advice for Scientists Starting a Lab

   Type

   Blog Post

   ...similarly to his advisor Wally Gilbert: “Very interdisciplinary, with emphasis on genetic engineering, sequencing...

7. Finding and Joining Your Dream Lab

   Type

   Blog Post

   ... finding and joining your dream lab, watch the webinar "How to Choose Your Next Lab" (updated 2020 version...

8. A Deep Dive into BioBuilder

   Type

   Blog Post

   ...use BioBuilder as an afterschool program or as a final project. BioBuilder’s open-access curriculum begins...

9. Improved Plasmid Maps Powered by SnapGene

   Type

   Blog Post

   ...be detected by our in-house software and also eliminates many of the extraneous ORFs that cluttered our...

10. Screening for Successful Genome Editing with Digital PCR

    Type

    Blog Post

    ... number of target DNA molecules present in the original sample with a great deal of precision. This means...

11. Behind the scenes: Addgene’s new search engine and more

    Type

    Blog Post

    ... new search tool, are the results of this multidisciplinary effort and cross-team collaboration (thanks...

12. Why and how to start studying chromatin (with Addgene's help)

    Type

    Blog Post

    ...transcription-associated DNA damage that promotes homologous recombination. Gong F, Chiu LY, Cox B, Aymard F, Clouaire ...

13. Choosing a CRISPR Nuclease: Site Accessibility, Specificity, and Sensitivity

    Type

    Blog Post

    ...available to researchers will continue to expand. Final thoughts Since the first use of Cas9 to engineer...

14. Hot Plasmids - June 2019 - Optogenetics, Acoustic Reporter Genes, microRNAs, and the CRISPR-Cas9 system CHIME

    Type

    Blog Post

    ...synaptic transmission. Cleavage of VAMP2 renders it inactive, thus inhibiting neurotransmitter release. How...

15. 15 Years of Addgene: The Top 15 Plasmids

    Type

    Blog Post

    ...Note: this plasmid was called pLKO-Tet-On in the original publication but its name was subsequently changed...

16. Plasmids 101: Methylation and Restriction Enzymes

    Type

    Blog Post

    ...as depicted in Lane 2. Controlling methylation Finally, you can control methylation by altering your choice...

17. Viral Vectors 101: Biosensors

    Type

    Blog Post

    ... Overview of AAV Encoded Calcium Biosensors Illuminating Epigenetics with a FRET Based Biosensor Fluorescent...

18. Viral Vectors 101: Types of viruses

    Type

    Blog Post

    ...is not currently known to cause any diseases. Recombinant AAV largely does not integrate, and the addition...

19. Plasmids 101: Blue-white Screening

    Type

    Blog Post

    .... (To be completely accurate, IPTG binds and inactivates the lac operon repressor, thereby allowing lac...

20. Pooled CRISPR Libraries Offer Genome-Wide Control for Large-Scale Functional Screens

    Type

    Blog Post

    ...consists of three components: 1. A nucleolytically inactive Cas9-VP64 fusion; 2. A sgRNA incorporating two...