We narrowed to 934 results for: TIM;
-
TypeBlog Post...activate the immune system, and of the infection to sometimes result in cell death, has led to interest in using...
-
Uncovering Ancestral Bias in CRISPR Research
TypeBlog Post...ancestry group. With the existing methodology, they estimate that the African ancestry-associated cancer dependencies... -
Plasmids 101: Secondary Nanobody Toolbox
TypeBlog Post...antibodies from its serum, and meticulously screening, optimizing, and characterizing several anti-mouse and -rabbit... -
Minigenomes - a Safe Way to Study Dangerous Viruses Like the Ebola Virus
TypeBlog Post...titration experiments might be helpful to achieve optimal results. It is important to note that this system... -
Your Lentiviral Plasmid FAQs Answered
TypeBlog Post... that a construct is functional before investing time and resources into making a stable cell line. When... -
Rett Syndrome: A History of Research and Therapeutic Outlooks
TypeBlog Post...Gail Mandel and her team have shown for the first time that programmable RNA editing can repair a gene ... -
Beyond the Blood Brain Barrier: PHP.B Enters the Central Nervous System Via the LY6A Receptor
TypeBlog Post...peripheral nervous system (PNS) targeting AAV Get 1st time AAV user tips from an AAV rookie Learn about some... -
Sonic Hedgehog? Sleeping Beauty? Learn About the Genes Behind Addgene’s Conference Room Names
TypeBlog Post...and Bagpipe. How does a gene get its name? Often times, a gene gets its name based on what happens to an... -
Controlling for Off-target Effects with a New Genome-wide CRISPR Screen Design
TypeBlog Post...libraries Overview of Library To better define the optimal conditions for CRISPR knockout screens, the Bassik... -
Plasmids 101: Shuttle Vectors
TypeBlog Post...vectors typically involves shuttle vectors, also sometimes called transfer vectors. The gene of interest ... -
Antibodies 101: Reading a Flow Plot
TypeBlog Post...annotated like so: CD14high or CD14low. Don’t be intimated if you’re struggling to understand how the researchers... -
Hot Plasmids Spring 2024
TypeBlog Post...lentiviral minus strand in the 3’ LTR. These optimizations produced 90% accurate integration of multiplexed... -
pCXLE toolkit: Efficient episomal plasmid-based method to reprogram peripheral blood cells to iPSCs
TypeBlog Post...episomal vector system generated by the group is an optimized mixture of three episomal plasmids (Table 1) encoding... -
Viral Vectors 101: Pseudotyping
TypeBlog Post...by nonspecific complement mechanisms in serum. Sometimes this is due to the cells that the viral vectors... -
Bacterial Toxin-antitoxin Systems as Molecular Biology Tools
TypeBlog Post...experiments. They’ve also helped researchers design and optimize cloning methodologies using counterselection. ... -
Plasmids 101: Gateway Cloning
TypeBlog Post...that will work well with a given set of resources, time, and experimental needs. Since its invention in ... -
CRISPR Activation: A Practical Guide
TypeBlog Post...appropriate isoform(s) of a given gene, as, many times, the isoform(s) common to a particular cell type... -
Adeno-associated Viruses (AAVs) for Genome Editing
TypeBlog Post...in vivo applications. Third, even in the most optimized tissue-culture based system, the efficiency of... -
Plasmids 101: Expressing shRNAs for RNA Interference
TypeBlog Post...dedicated field of study for improving these tools. Next time you need to knock down a gene, maybe you’ll consider... -
Antibodies 101: Beyond Surface Labeling
TypeBlog Post...using biorender.com. Intracellular labeling Oftentimes, a marker of interest is not located on the cell...