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Addgene

Enter a sequence to perform a BLAST-based search of Addgene plasmid sequence databases.

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We narrowed to 1,019 results for: CAL;

Showing: 921 - 940 of 1019 results

  2. Molecular Biology Reference

    Type
    Guide
    ...purification of cellular components, such as DNA, but practically this isolation is only feasible for relatively...Plasmids are fragments of double-stranded DNA that typically carry genes and can replicate independently from...and eukaryotes, they play the most significant biological role in bacteria where they can be passed from...to the field of recombinant DNA, in which many identical DNA fragments can be generated. The combination... 6000 basepairs) to enable easy manipulation. Typically plasmids contain the minimum essential DNA sequences... DNA, and this process of generating multiple identical copies of a recombinant DNA molecule is known ...manipulate genes and other genetic elements using specifically engineered plasmids, commonly referred to as...

  12. Adeno-associated virus (AAV) Guide

    Type
    Guide
    ...organism to target large or diffused biological structures. Specifically, researchers were interested in creating...two ITRs with a gene expression cassette that typically contains the transgene of interest. The size of...be included between the ITRs is limited by the physical space available inside of the small AAV capsid...host’s genome. Instead, the linear rAAV DNA is typically processed into a double-stranded circular episome...episomes or concatemers. This avoids the effects local chromatin structures in the host genome can have...gene therapy, neuroscience research, and other biomedical fields. Gene Therapy One of the major applications...A and B, and Duchenne muscular dystrophy. Many clinical trials of AAV-based gene therapies are underway...
Showing: 921 - 940 of 1019 results