We narrowed to 172 results for: TOX

1. What's New in CRISPR - September 2019

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   ...phage host factors, and identify sequence-specific toxicity of Cas9. Read the paper in Nature Communications...

2. Mapping the 4D nucleome with CRISPR/Cas9

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   ...illumination settings, lowering photobleaching and phototoxicity concerns and extending the potential imaging...

3. In Living Color: The Skinny on In Vivo Imaging Tools

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   ...them brighter, more photostable, smaller, and less toxic to cells. They’d like to make near-infrared fluorescent...

4. Lentiviral CRISPR Libraries Enable Genome-Scale, Knockout Screening

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   ...library to screen for genes involved in bacterial toxin resistance, identifying 4 previously unknown genes...

5. 28 Hot Plasmid Technologies from 2015

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   Blog Post

   ...systems due to its large cargo capacity, minimal cytotoxicity, and broad host-tropism. These tools open up...order to avoid complicating effects from global toxicity due to loss of splicing. To this end, destabilizing...

6. An Addgene Summer Internship

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   ...had restrictions. It couldn’t be a Covid gene, a toxin, or an oncogene, for safety reasons, and the insert...

7. Addgene-Seeding Labs Plasmid Grant: Accelerating Science Globally - 5 Scientists, 4 Countries & 3 Continents!

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   ...recombinant Cry proteins will then be screened for toxicity against local insect pests. By developing biological...

8. Choosing a Good Mentor for Scientists

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   ...their answers to your questions. Consider reading Toxic Academic Mentors by @drmellivora, an excellent blog...

9. Tetbow: Bright Multicolor Labeling for Neuronal Tracing

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   ...you should not wait too long, as too much XFP is toxic to the cells. Inadequate expression levels of XFPs...

10. Rewiring Metabolic Circuitry with CRISPR RNA Scaffolds [Video]

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    ...will likely prove particularly useful in avoiding toxic intermediate buildup as well as controlling cell...

11. Hot Plasmids: FRET-Based Biosensors

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    ...These are essential metal ions, but they are also toxic,” Merkx explained. New tools were needed to measure...

12. Predicting Adverse Reactions to Monoclonal Antibody Drugs

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    ...L., & Burns-Naas, L. A. (2015). Chapter 27—Immunotoxicology Testing of Monoclonal Antibodies in Macaca...

13. FlipGFP, a novel fluorescence protease reporter to study apoptosis

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    ...Apoptosis: a review of programmed cell death." Toxicologic pathology 35.4 (2007): 495-516. PubMed PMID: ...

14. Photosensitizer Induced Cell Ablation with FAP-TAP MG-2I-dL5**

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    ...increase cell ablation efficiency, but dL5** phototoxocity is induced when expressed on the cell surface...

15. R Bodies: Membrane-Rupturing Microscopic Tools

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    ...role of R-bodies in the killer trait: Absence of toxicity of R-body producing recombinant E. coli on paramecia...

16. Synthetic Photobiology: Optogenetics for E. coli

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    Blog Post

    ...a number of reasons, including their potential toxicity and cross-reactivity with other pathways. Since...

17. Viral Vectors 101: The AAV Retrograde Serotype

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    ...perform retrograde tracing, but often at the cost of toxicity, low expression, or poor scalability.  Scientists...

18. Viral Vectors 101: Viral Applications

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    ...plasmid. Viral transduction is also generally less toxic to cells than transfections, preserving cell viability...

19. Plasmids 101: Inducible Promoters

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    ...Leakiness If you’re expressing a gene that may be toxic, it’s important that your inducible promoter not...

20. Back to Bacteria: CRISPR gRNA Multiplexing Using tRNAs

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    ...As nucleases may have off-target effects and/or toxicity, it would be advantageous to instead use a preexisting...