We narrowed to 335 results for: dre
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TypeGuide... than ideal. DREADDs Designer Receptors Exclusively Activated by Designer Drugs (DREADDs), like RASSLs...currently two Gi DREADDs based on human muscarinic receptors, hM2Di and hM4Di, and a Gi DREADD based on the...turkey erythrocyte β-adrenergic receptor with a rat M3 muscarinic receptor. This DREADD was shown to have...used in vivo . Figure 2: DREADDs, their ligands, and signaling properties. DREADD Ligands Muscarinic-receptor...activity. Table 1. Descriptions of DREADDs and their activity in neurons DREADD Receptor Effector Ligand Effect...of alternative DREADD ligands, please see the text. Browse Addgene's collection of DREADD plasmids ! PSAMs...activator or inhibitor, respectively. DREADDs or PSAMs or LMOs. DREADDs are monomeric proteins, while PSAMs...
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Advice on Career Paths and the Green Card Process for International Researchers and Entrepreneurs
TypeBlog Post...your visa and or green card process well before addressing your career alternatives in order to put you ...you in the best position to land your dream job. All of the immigration options discussed in this post benefit... invitation to be a peer reviewer needs to be addressed to your own personal email directly. EB-1B outstanding... -
Participate in the Pets of Addgene Scavenger Hunt
TypeBlog Post...enter the raffle, you’ll enter your name and email address. If you’re selected in the raffle, you will receive...receive an email from us asking for your mailing address and T shirt size. You have until April 7, 2021... -
Using AAV for Neuronal Tracing
TypeBlog Post...viral proteins VP1, VP2, and VP3. To date several hundred variants, or serotypes, have been found naturally... an anterograde tracer and injected at several hundred sites across the entire mouse brain. Traced neurons...PubMed Central PMCID: PMC2698947. Merkel, S.F., Andrews, A.M., Lutton, E.M., Mu, D., Hudry, E., Hyman, ... -
Addgene’s New Way to Help You Share Science
TypeBlog Post... discoveries!” I knew right then I had found my dream job, because one thing I learned in grad school ...I also spend a lot of time listening. I’ve had hundreds of conversations with PIs, lab managers, and grad... -
Countdown to Halloween @Addgene
TypeBlog Post...customer support by dressing up as our Zendesk email system. Our 2013 winners dressed up as Addgene's favorite... -
CRISPR Guide
TypeCollection...locus. Chromosome painting requires delivery of hundreds of gRNAs with target sites throughout the chromosome... -
A new platform for fast functional characterization of potentially cancerous mutations
TypeBlog Post...mutations, and the group has deposited several hundred plasmids from this study with Addgene. Read on ... are represented in this collection along with hundreds of less well-studied candidates. The possibilities... -
CRISPR Protocol for Genomic Deletions in Mammalian Cell Lines [Video]
TypeBlog Post... by Daniel Bauer and Matthew Canver of Boston Children’s Hospital and Harvard Medical School. Addgene ...hematologist and principal investigator at Boston Children’s Hospital and Harvard Medical School. His lab ... -
Celebrating Accomplishments in the Lab
TypeBlog Post...years, learning “lots of interesting things from children, their classmates, and parents”. He also cooks...Choosing a Research Project Finding and Joining Your Dream Lab Advice for Choosing a Research Project Advice... -
Spurred by COVID-19, Addgene Bridges Plasmid Sharing Between Academia and Industry
TypeBlog Post...industry-based scientific community. Conversations with children playing in the background became a normal occurrence...of Illinois Chicago Boston Children's Hospital California... -
IBEX Knowledge-Base: A Data Resource for Multiplex Tissue Imaging
TypeBlog Post...why scientists from around the world, including Andrea Radtke, PhD, and Ziv Yaniv, PhD, have created the...around the world can ask and answer questions. Andrea and Ziv were inspired by the open-software community... -
A Better Way to Get Customer Support: The Help Center
TypeBlog Post...Luckily, there’s a trend in customer support to address this exact problem, and it’s called “self-service...will be be prompted to enter your name and email address, after which you can describe your issue and press... -
Future of Research Conference - Remarkable Opening Session
TypeBlog Post...workforce. The soft money system needs to be addressed. We should tackle the issues with rules and practices...change in the way we train scientists to start addressing this problem. Finally, one point made by Dr.... -
Chemogenetics vs. Optogenetics: Which Method Should I Choose?
TypeBlog Post...wavelength reach receptors in the brain. One way to address this is by working with organisms with light accessible...expertise with us. References Urban DJ, Roth BL (2015) DREADDs (Designer Receptors Exclusively Activated by Designer... -
Bringing Sustainable Practices to the Lab: Recycling
TypeBlog Post...generated. This is a systemic problem that we need to address, but is often ignored in the lab environment. ...shipping label. To return the box, simply peel your address sticker off the box, remove the ice pack (it’s ... -
Addgene at the ASM Microbe 2016 Conference
TypeBlog Post...Thursday evening, I stayed to see the Opening Keynote address with Bill Gates. The long line for bag check was...conference Addgenies were lucky enough to meet hundreds of the over 11,000 conference registrants, including... -
Summer SciComm Series: Master of SciComm
TypeBlog Post...I didn’t truly address the question of what I wanted to do when I grew up until I was all but finished...Departments like ours reflect a growing effort to address this obstacle in its many forms. A short stroll... -
Addgene Begins Distribution of Recombinant Antibodies
TypeBlog Post...frequently cited antibodies for use in brain imaging (Andrews et al., 2019), validated in both western blot and...antibody sharing landscape as well. References Andrews NP, Boeckman JX, Manning CF, Nguyen JT, Bechtold... -
Addgene Receives NIH BRAIN Initiative Grant to Create Open-Access Recombinant Antibody Resource
TypeBlog Post...from the National Institutes of Health that will address this problem.The grant, which is part of the NIH... IC, Tandon AK, Anderson S, Bladen CL, Jones B, Aldred SF, Bestagno M, Burrone O, Maynard J, Ferrara F...