We narrowed to 1,137 results for: CAN

...DNA to you, we'd save you days of time so that you can begin your cloning experiment right away. And without...multiple plasmids in one cell, it might be that you can't stably maintain them in the cell. This blog post...

...Tracer Library Has Been Used in Cancer Lineage Tracing Read How CRISPR Can Be Used in Genome-Wide Screening...When cancers are treated with drugs designed to hit them right where it hurts, the effects are often ...is that, in a relatively short amount of time, cancers become resistant to drugs, particularly targeted... yet have a comprehensive understanding of how cancers become resistant, an emerging theme is that they...differentiation.” https://www.addgene.org/kits/sabatini-wood-cancer-pathway-orfs/ Finding signaling pathways involved...signaling pathways that are frequently implicated in cancer cell proliferation, survival, differentiation, ... usable for pooled screens. Applications of the cancer pathways ORFs kit Wood and his colleagues developed...

... the Scale: NSF's Career Life-Balance Initiative Can Scientists Maintain a Good Work-Life Balance? Read...

...working at Addgene. We’re a small non-profit, so we can only provide free food on special occasions. However...

...space in the viral genome so that a gene of interest can be packaged into the virus instead.  Next let’s take...

...fold higher expression levels compared to AAV9. You can now target these cells with AAV-CAG-GFP packaged ...

...vector containing a gRNA. These transduced stem cells can be implanted in irradiated recipients to create mice...phosphatases, PTPN1 and PTPN2, which are of interest as cancer immunotherapy targets but are embryonic lethal,...interested in improving CD8+ T cell responses to cancer.     References and resources References LaFleur...

...run or risk minor electrocution.  These days you can buy small gel boxes, but none as small as the baby...to throw out chipped or imperfect equipment.  We can’t safely recycle these materials either.  Test tubes...

...questions.   Advice for success in academia How can we shape our time in academia to maximize productivity...

...possible with conventional FPs. In addition, PA FPs can improve the achievable signal-to-background ratio...resolution images in vivo. “One of the reasons we can’t localize one cell at a depth of one centimeter with...

...products is desired, as multiple selection markers can ensure that all desired tags have been integrated...

...project the expression of isolated bacterial proteins can be achieved using a bacterial expression system such...expression of nutritionally and therapeutically significant proteins. In this project she aims to create ...essential, which means that the body requires them but cannot produce them. By using yeast integration vectors...

...term "nonprofit" is a bit misleading. Nonprofits can generate revenue (as Addgene does through materials...service organization like the Red Cross or the American Cancer Society, or maybe you think about a local food...do with their revenue. A nonprofit organization cannot distribute profits to private individuals through...

...describe how a better understanding of Cas9 biophysics can help enhance HDR. CRISPR 101: Ribonucleoprotein (...

...Running4Rare are paired with patient partners so that they can help tell their stories. I was paired with a six-...named AJ Gonzales who suffers from Fibrodysplasia ossificans progressiva (AKA FOP). This terrible disease ...always work as efficiently in humans. This is why we cannot stop searching for novel solutions to treat rare...

...serotypes. Not sure what to request? Addgene's Data Hub can help, with over 100 user-submitted viral vector reports...pAAV-EF1α-F-FLEX-mNaChBac-T2A-tdTomato AAV8 Molecular tool Massimo Scanziani New viral prep pAAV_hSyn1-SIO-stGtACR2-FusionRed...

...challenges of creating biological circuits, and I can only say this science is really, really hard. That...

...New Yorker’s “Comma Queen” shows how punctuation can be wildly funny as well as financially critical. ...and jobs. At Science, which is published by the American Association for the Advancement of Science (AAAS...Senior Editor at Science magazine, published by the American Association for the Advancement of Science. She...

... CD9 (a known marker molecule for microvesicles) can further improve AAV yields as CD9 is thought to enhance...

... be unable to get into the target cells and this can be detected via loss of luminescence.     B.1.351...