We narrowed to 997 results for: lars;

...easy to navigate. We also updated some our most popular CRISPR blogs to keep them current. Here are some...plasmid class covered on that page. To help you find popular plasmids, we’ve also added four new plasmid pages...mammalian systems, bacteria, plants, and yeast. Popular cytosine base editor pCMV-BE3 has been requested...only the specified RNA target. Bonus: It displays similar on-target activity to siRNA, but with far fewer...

...control over neuronal activity. While they serve similar purposes, both techniques offer researchers different...have faster off kinetics and allow neurons to repolarize faster.  Chemogenetics does not offer the same...targeted to specific tissues, cell types or even subcellular regions of a neuron. Optogenetic approaches excel...with light accessible brains, such as zebrafish larvae. Mouse studies, however, require a permanent intracranial...

...General Assembly has declared 2024 the International Year of Camelids. The declaration is intended to raise...antibodies in the serum of a camel and soon after found similar antibodies in llamas and alpacas (Figure 1). At... tissues. sdAbs can also be used to manipulate cellular functions, like in this early example we highlighted...

...researchers and ready access to stably archived large-scale datasets by computational biologists. ...genome-wide datasets, which are often obscured in large supplementary data files, BioGRID ORCS makes it ... interest. In addition, users interested in a particular disease, cell type or drug treatment can browse...used to search the entire CRISPR database for particular screens of interest.   Figure 3: Each ...

...Addgene. This is particularly true in my position as an Outreach Scientist where I spend a large amount of my...pretty hefty bumps during my graduate training. I particularly think that too many young scientists are led...experience is key to my current position, I think it’s largely my work developing myself as a science communicator...

...clustered regularly interspaced palindromic repeats) Cas (CRISPR associated genes) system. This popular genome...polythetic classification based on evolutionary similarity (5). Type II CRISPR/Cas is the system that scientists...translatable to the other CRISPR subtypes. Still, the large and dynamic range of CRISPR systems between and ...

... by Torsten Wittmann’s lab at UCSF to modulate cellular dynamics with light by modifying EB1. EB1 normally... opens novel ways in manipulating and studying cellular dynamics. The photoinducible control of protein...potential use for a wide range of applications in cellular biology. Van Haren J et al. Nature Cell Biology...the base editing podcast segment The increasing popularity of single base-editors has resulted in the rapid...

...to learn much more about cellular DNA repair pathways. An emphasis on cellular repair post-CRISPR cleavage...Twitter if you missed our live updates! My most popular tweet from the conference is shown above. The blog..., which alter genomic DNA without the need for cellular HDR.   Having had time to digest my notes, since...

...talk about Z DNA that inspired her to major in molecular biology in college. She then pursued a PhD in ...not only got incredibly compelled by wet bench molecular research, but also became passionate about virology...of Viral Vectors Karen Guerin for the journal Molecular Therapy. Vandenberge is also the Grousbeck Family... Gene Therapy Center, Associate Director of the Ocular Genomics Institute, and an Associate Member at ...

...fluorescence allows for clear distinction between vacuolar/lysosomal and cytoplasmic Rosella. When fused ...biosensor is the GFP-LC3-RFP-LC3ΔG probe. It’s similar to the mRFP-GFP-LC3 Tandem Fluorescent Protein,...Rosella: a fluorescent pH-biosensor for reporting vacuolar turnover of cytosol and organelles in yeast." ...measuring autophagy." International journal of molecular sciences 18.9 (2017): 1865.  PubMed PMID: 28846632...