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We narrowed to 997 results for: lars;

Showing: 521 - 530 of 997 results
  1. Antibodies 101: Epitope Availability

    Type
    Blog Post
    ...If you work in a lab that regularly does immunoimaging, there’s likely a large collection of antibodies...specific to denatured versions, or even to just that particular assay.      Fig. 1: A native protein ...that has been validated for an assay that uses similar sample preparation - for instance, if you cannot...
  2. Plasmids 101: A Brief History of Plasmids and an Improved eBook!

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    Blog Post
    ...their name? In 1952, Joshua Lederberg set out to clarify the classification of these cytoplasmic inheritance...began to study other extrachromosomal particles, particularly Resistance or R-factors. Like F-factors, R-factors...especially lambda, was the tool of choice for molecular biologists wanting to study bacterial genetics...pSC101 became the first plasmid cloning vector and molecular biology was never the same. Over the next few ...
  3. Mentoring for Scientists: I Have a Mentor, What Now?

    Type
    Blog Post
    ...meetings or calls regularly and don’t cancel, so that you drive progress with regular accountability checks...Mentoring for Scientists Guide.  You can use it to clarify and discuss values. The activity is just the start...Relevant, and Time-bound. It is a good idea to take larger goals (e.g. Figure out what I want to do after ...
  4. New and Upcoming Viral Vectors - June 2019

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    Blog Post
    ...often have to choose the best serotype for their particular study, which includes comparing the transduction...samples are available in various serotypes of two popular control AAV encoding GFP. Check out our inventory...variant provides improved detection for tracking large populations of neurons in wide-field imaging (Dana...on availability date or to be notified when a particular catalog item is available for order please email...
  5. FlipGFP, a novel fluorescence protease reporter to study apoptosis

    Type
    Blog Post
    ...are responsible for the degradation of over 600 cellular components ultimately leading to cell fragmentation... scientists need a protease reporter that has a large dynamic range and high brightness. The Shu Lab from... pattern was consistent with TUNEL staining, a popular method to observe apoptotic cells. Lastly, the ...FlipGFP is a novel fluorogenic reporter that has a large dynamic range and high brightness. This reporter...
  6. Addgene Depositors Get More Citations

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    Blog Post
    ...outlier, this story had us wondering: is there a larger trend here? Do papers associated with Addgene deposits...deposits are more highly cited, we went to one of the largest bibliographic databases available, Web of Science...Biotechnology & Applied Microbiology, Biochemistry & Molecular Biology, and Biochemical Research Methods. We ...at the MIT Sloan School of Management. She is particularly interested in exploring how innovative tools...
  7. "Build Your Plasmid": The Game - Play to Teach

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    Blog Post
    ...drastically alter your strategy. I realized that similar types of thinking go into developing gene therapy...PLASMID is a game where you need to apply basic molecular biology, cell biology, microbiology, genetic engineering... He is also founder and consultant at FRESCI particularly interested in advanced in vitro models technology...Resource Center Resources on Addgene.org Find molecular biology educational resources Find protocol videos...
  8. FPbase: A new community-editable fluorescent protein database

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    Blog Post
    ...FPs are tremendously complicated entities with a large range of characteristics (color, brightness, photostability... a project written in Python & Django, using a popular database management system (PostgreSQL), that aims...use case for FPbase is finding information on a particular FP; this can be done directly using the search...your help!), I believe this represents one of the largest available online collections of FP spectra. Every...
  9. The Importance of High Titer for AAV Transductions

    Type
    Blog Post
    ...the cell, and potentially spread out over an even larger area, thus necessitating even higher retrograde...methods to improve AAV production.     References 1.Clark, K. Reed. "Recent advances in recombinant adeno-...Adeno-associated Virus Transduction and Integration. Molecular therapy : the journal of the American Society ...anterograde transsynaptic tagging: mapping corticocollicular input-defined neural pathways for defense ...
  10. R Bodies: Membrane-Rupturing Microscopic Tools

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    Blog Post
    ...orchestrated movements of networks of proteins consuming molecular fuel sources. While the importance of understanding... realized that these mutations clustered in a particular region of the R-body. Further mutatgenesis of...penetrate other barriers (like vasculature or extracellular matrices) in response to pH changes. Beyond...
Showing: 521 - 530 of 997 results