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We narrowed to 961 results for: ARC

Showing: 561 - 570 of 961 results

  1. Antibodies 101: Conjugation

    Type
    Blog Post
    ...out plenty of roles just the way they are, the research antibodies in your refrigerator often need a little...are kind of hard to see. To solve this issue, researchers conjugate various labels to antibodies that produce...conjugation, which is commonly used for labeling research antibodies. Lysine residues are found throughout...

  2. What's New in CRISPR - November 2021

    Type
    Blog Post
    ...recently identified Cas12f systems from uncultivated archaea are much smaller and would be ideal for such AAV...system (CasMINI) engineered from the uncultivated archaea Cas12f (Un1Cas12f1, or Cas14a1) system. The CasMINI...editing efficiency. The lab also optimized the architecture and amino acid sequence of the prime editor,...

  3. RNA Extraction Without A Kit

    Type
    Blog Post
    ...of the different steps in RNA extraction. Researchers at the NIH in the mid 1980’s set out to develop...with chloroform as in the above no-kit method.  Researchers have also developed ways to “stabilize” RNA within...gene expression. There are several things that researchers can do to combat this issue. First and foremost...

  6. CRISPRainbow and Genome Visualization

    Type
    Blog Post
    ...Colorful CRISPR technologies are helping researchers visualize the genome and its organization within...low resolution and can’t be used in vivo. Some researchers have used fluorescently tagged DNA-binding proteins...CRISPR. Early CRISPR labeling techniques allowed researchers to visualize nearly any single genomic locus,...

  7. Plasmids 101: Cre-lox

    Type
    Blog Post
    ...as part of its natural viral life-cycle, and researchers have adapted the components for use in genome...-lox? The Cre/lox system is a well-established research tool, especially in the field of mouse transgenics...parallel. Have you used the Cre-lox system in your research? Do you have any tips or tricks, or clever cre-dependent...

  8. CRISPR 101: Anti-CRISPR Proteins Switch Off CRISPR-Cas Systems

    Type
    Blog Post
    ..., Doxzen KW, Ma E, Liu J-J, Knott GJ, Edraki A, Garcia B, Amrani N, Chen JS, Cofsky JC, Kranzusch PJ, .../10.3390/v10120695 Pawluk A, Amrani N, Zhang Y, Garcia B, Hidalgo-Reyes Y, Lee J, Edraki A, Shah M, Sontheimer... on Addgene.org Find CRISPR Plasmids for Your Research Interested in light-inducible Cas9 activity? Check...

  9. Meet an Addgenie: Insights into Grad School, Career Paths, and More

    Type
    Blog Post
    ... doesn’t mean you’ve failed. “I got a job as a research assistant in a lab at the university that I went...choice, but by circumstance. She was working as a research and technical assistant, when her life changed...often under a lot of pressure to publish their research and are not so keen on sharing their results in...

  10. Mouse Modeling, Part 1: Genetically Engineered Mice

    Type
    Blog Post
    ...provide researchers with useful and adaptable tools to perform basic and preclinical research. For scientists...Inbred and outbred strains Mouse strains used in research can fall under one of two broad classifications...
Showing: 561 - 570 of 961 results