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  1. Kiran Musunuru on the Newest TALEN Genome-Editing System

    Type
    Blog Post
    ...Cell, Musunuru, Chad Cowan and their colleagues describe a much more efficient tool for doing that disease...people unfamiliar with this new TALEN kit, can you describe it for us? Musunuru: TALENs are a type of genome...
  2. What's New in CRISPR - November 2021

    Type
    Blog Post
    ...read more content related to CRISPR technology, subscribe to our CRISPR blog content.   In this post we ...miniature CRISPR-Cas12f nuclease Quanjiang Ji’s lab describes an effective miniature Cas system that utilizes...
  3. dTAG - You're it!

    Type
    Blog Post
    ...locus-specific knock-in of FKBP12F36V. Detailed protocols describing the use of these plasmids are available here....degradation, and lead author on the recent paper describing the dTAG technology. Follow him on twitter @behnamnabet...
  4. Zinc Finger Consortium Reagents

    Type
    Collection
    ...and educational use. Links to additional pages describing these reagents are provided below: Zinc Finger...
  5. CRISPR 101: Targeting Non-Coding RNAs with CRISPR/Cas9

    Type
    Blog Post
    ... coming, right? Non-coding RNAs (ncRNAs) are transcribed but do not encode proteins. They play important...sequence can completely disrupt expression of the transcribed ncRNA (Jiang et al. 2014).  Simple knock-out ...
  6. Fluorescent Proteins 101: Introduction to FRET

    Type
    Blog Post
    ...Resonance Energy Transfer (FRET) was originally described by Theodor Förster in 1948 as a variation of the...FRET probe, try searching PubMed for articles describing the FRET tool that you are looking for and check...
  7. Quickest Way to Deposit Plasmids: The Deposit Spreadsheet

    Type
    Blog Post
    ... in red in the spreadsheet (Figure 2) and are described in Table 1. Some cells have drop-down options ... Primary Vector Type The vector type should describe how your plasmid is intended to be used. Choose...
  8. CRISPR Plasmids - Epigenetics

    Type
    Collection
    ...encyclopedia of Class 2 CRISPR systems with wiki entries describing enzyme activity, experimental considerations,...
  9. CRISPR Plasmids - RNA Editing

    Type
    Collection
    ...encyclopedia of CRISPR systems with wiki entries describing enzyme activity, experimental considerations,...
  10. Viral Vectors 101: Voltage Indicators

    Type
    Blog Post
    ...component as well as a small molecule which we will describe in more detail below. Types of Voltage Indicators...membrane, a concern with several of the previously described systems. Several adaptations of this method have...
  11. Plasmids 101: Protein Expression

    Type
    Blog Post
    ...synthesize a particular protein DNA must first be transcribed into messenger RNA (mRNA). mRNA can then be translated...template of choice and allowing these cells to transcribe, translate and modify your protein of interest...
  12. AAV Vector Quality Control: Going the Extra Mile with NGS

    Type
    Blog Post
    ...transduced cells whenever possible. This post will describe our workflow for viral genome sequencing (VGS)...Check out our Viral Vectors Featured Topic Page Subscribe to Viral Vectors Blog Posts Learn How We Use NGS...
Showing: 101 - 120 of 382 results