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We narrowed to 581 results for: arl

Showing: 121 - 140 of 581 results

  1. Editor's Choice, August 2016

    Type
    Blog Post
    ...number of out of office responses I’ve received). Clearly we have all of our writers to thank for the excellent...who wrote this month’s most popular blog post on early user experiences with CRISPR alternative, NgAgo....having trouble, to determine if there have been any early successes, and to find out what delivery techniques...

  2. Management for Scientists: Seeking Feedback

    Type
    Blog Post
    ...reinventing the wheel is inefficient. An effective team regularly seeks expertise wherever it can be found. Listen...allies" – these are employees in your group that regularly step up to give feedback and fill you in on percolating...constructive input from your team: Solicit feedback regularly and often A one-time event doesn't work to get...

  3. Phage Directory: From Phage Therapy to a Repository of Phage Information

    Type
    Blog Post
    ...the directory does not typically come out until nearly the last minute when all other options have been... phage alerts can be sent out to the directory earlier, but the researchers in the directory are volunteering...time and resources and there is a chance that an early request for phage may not be needed if other antibiotics...

  4. ReFigure: Save Scientific Figures into Dashboards and Share Your Insights

    Type
    Blog Post
    ...resulting in “negative data” often dominate the early years of a project. Dissemination of the knowledge...selection of data found in full-length publications. As early career researchers, we wondered how we could make... guest blogger Girija Goyal! Girija Goyal is an early career researcher and cofounded ReFigure with Joe...

  5. History of CRISPR Cas - A tale of survival and evolution

    Type
    Blog Post
    ...biological blockbuster known as the CRISPR (clustered regularly interspaced palindromic repeats) Cas (CRISPR associated...have been identified that neutralize CRISPR/Cas. Earlier this year, expression of 1 of 5 anti-CRISPR genes... Mali P, Yang L, Esvelt KM, Aach J, Guell M, DiCarlo JE, Norville JE, Church GM. Science. 2013 Jan;  ...

  6. Science Careers: Unruly Interests Feed Many Paths

    Type
    Blog Post
    ... a look at the blog ‘Scholarly Kitchen’ for a glimpse into the world of scholarly publishing. And see ...developing a career Developmental biology caught me early on: a simple egg is packed with information. I am...

  7. Plasmids 101: A Brief History of Plasmids and an Improved eBook!

    Type
    Blog Post
    ...began to study other extrachromosomal particles, particularly Resistance or R-factors. Like F-factors, R-factors...napkins to notebooks Although discovered in the early 1950s, it took until the 1970s for plasmids to gain...Stanley Falkow, Stanley Cohen, Herbert Boyer, and Charles Brinton concocted a wild idea of using the newly...

  8. Don’t Wait To Launch Your Health Science Startup

    Type
    Blog Post
    ...miLab, a Boston-based startup focused on empowering early-stage scientists. You can think of miLab as a sort... next generation companies.  We launched in the early spring of 2015 and since that time have received...capital for such a fund is an impossibility at our early stage.  After each pitch we made, we considered ...

  10. Addgene Depositors Get More Citations

    Type
    Blog Post
    ...original 2013 gene editing paper on CRISPR/Cas amassed nearly 2,400 citations in its first four years (1). In... over 6,500 requests for these plasmids. While clearly an outlier, this story had us wondering: is there...at the MIT Sloan School of Management. She is particularly interested in exploring how innovative tools...

  11. With Our New Viral Service, We're Taking CRISPR Further!

    Type
    Blog Post
    ...that, for many groups, may not be worthwhile. Particularly if in the end all they want to do is to quickly...size of the SpCas9 nuclease (~4.2 kb) this is a particularly prominent problem in CRISPR genome editing experiments...ready-to-use lentiviral preps. Each library uses nearly 80,000 gRNAs to target around 20,000 individual...

  12. Management for Scientists: Delegating is Key

    Type
    Blog Post
    ...assignee and this is a recipe for bad outcomes. Clearly articulate the desired outcomes. Begin with the... the heart of delegating for success.  Meet regularly before during and after the assignment to discuss...calendar even if it is just 15 minutes a week. Clearly identify constraints and boundaries. Where are ...

  13. Advice for Scientists Starting a Lab

    Type
    Blog Post
    ...and a friend. George Church runs his lab fairly similarly to his advisor Wally Gilbert: “Very interdisciplinary...Institute (HHMI) offers some great resources for Early Career Scientists, including their "Making the Right... EMBO Lab Leadership Courses HHMI Resources for Early Career Scientists Science Careers: Running Your ...

  14. Antibodies 101: Flow Cytometry Controls

    Type
    Blog Post
    ...antibody companies or check the literature. Pro tip! Early gates, like your live/dead markers or commonly used...isotype controls An isotype sample is prepared very similarly to a FMO sample: you make a sample from a combined...immunotherapies. She is currently a research technician in Arlene Sharpe's lab at Harvard Medical School.   More...

  15. Sweating the Small Stuff: Details in the Lab

    Type
    Blog Post
    ...What fixed it was not trying even harder to start earlier, but simply moving all my prep work to the day ...would build a wall of pipette tip boxes when she particularly needed to focus, which was extremely effective... Guide to Getting Started in Undergrad Research Early Career Researcher Toolbox  8 Tactics for Choosing...

  16. Improved Plasmid Maps Powered by SnapGene

    Type
    Blog Post
    ...software. In fact, SnapGene’s feature library includes nearly 3x as many features as could be detected by our...extraneous ORFs that cluttered our old plasmid maps. Clearly Annotated Features, Enzymes, and Primers - The ...start thinking about your next cloning experiment early on. Beyond these simple but powerful display improvements...

  17. Transferable Skills Guide: Public Speaking

    Type
    Blog Post
    ... in front of an audience and convey your ideas clearly and strategically is powerful in almost any career...and/or apprehensive. I still get nervous quite regularly, and I've had multiple jobs where all I did was...developed a valuable skill set that will be useful in nearly any other job you may choose to pursue. So take...

  18. All in a Twist: dsRNA

    Type
    Blog Post
    ...in dsRNA generation. While these molecules are clearly associated with cellular damage and dysfunction... acid hybrids are always around. R-loops are particularly enriched in highly transcribed regions and repetitive...responses can mount in the absence of infection. Similarly, if endogenously synthesized dsRNA finds its way...

  19. The Breast Cancer Microenvironment: A Tumor’s Backstage Team

    Type
    Blog Post
    ...Centro Ciência Viva" in Aveiro, Portugal. She is particularly interested in science journalism and writing...PMID: 15261139. Barsky, Sanford H., and Nina J. Karlin. "Myoepithelial cells: autocrine and paracrine ...absence of stromal caveolin-1 expression predicts early tumor recurrence and poor clinical outcome in human...

  20. Summer SciComm Series: Cognitive Load

    Type
    Blog Post
    ...that you think are clearly connected, step back and ask yourself, “are these clearly connected because ...you understand why you’re not communicating as clearly as you intended (it happens to us all!) and offer...
Showing: 121 - 140 of 581 results