We narrowed to 335 results for: dre
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TypeBlog Post...to have occurred that was passed down to the grandchildren; in this study,epigenetic changes were statistically...influenced cardiovascular mortality of the female grandchildren." BMC genetics15.1 (2014): 12. PubMed PMID: ...
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Transferable Skills: Negotiation
TypeBlog Post... also negotiate with friends, partners, and/or children about everything from what you’re going to eat... takes the earlier slot agrees to pick up both children while the other person uses an available after-hours... -
Hot Plasmids and Viral Preps - May 2021
TypeBlog Post...include Flp-dependent DREADDs viral vectors. Both inhibitory and excitatory DREADDS from the Gether lab ... -
Multiplexed Capture of Promoter-enhancer 3D Chromatin Structures Using CRISPR
TypeBlog Post...original CAPTURE method was published in 2017 and addressed many of the drawbacks of 3C methods, but could...CAPTURE that detects chromatin interactions at hundreds of loci at once (Liu et al., 2020). CRISPR Affinity... -
PRIDICT: Predicting Efficiencies of Prime Editing Guide RNAs
TypeBlog Post...modifications. Since this means we could design hundreds to thousands of different pegRNAs for each desired...the use of prime editing in pooled settings with hundreds to thousands of pegRNAs. Chromatin-based prime... -
Transferable Skills Guide: Managing a Team
TypeBlog Post...high-performing team - which is every manager’s dream. Learn to delegate effectively As a manager your...performance or behavior is inadequate, you need to address it as soon as possible for the best outcome. Nobody... -
Addgene's Cancer Collection Pages Connect the Research Community
TypeBlog Post...pathways involved in the development of cancer. With hundreds of genes involved in the Ras pathway alone and.... PubMed Central PMCID: PMC4353587. 2. Stephen, Andrew G., et al. "Dragging ras back in the ring." Cancer... -
Experimenting with New Careers while in Grad School
TypeBlog Post... of "The world’s biggest and best children’s museum", The Children's Museum of Indianapolis. I drove passed... -
Transgenic Organisms, Cas9 Gene Drives, and Appropriate Safeguards
TypeBlog Post...It's a tremendously promising field that could address many pressing global problems in health, agriculture...dengue for many years. Since more than a thousand children died of malaria today, let's not risk a potential... -
Which Fluorescent Protein Should I Use?
TypeBlog Post...the family of FPs just keeps getting larger with hundreds of variants available. Read on to familiarize ...proteins are reversibly switchable (e.g. rsEGFP, Dreiklang). Fluorescent Timers (FT): These proteins change... -
Negative Can Be Positive: Open AAV Data with Addgene
TypeBlog Post...serotypes (AAV1, 8, 9) injected into the A2 noradrenergic area of the caudal NST. (A-C) Low-magnification...isolated case. Our scientific support team answers hundreds of AAV questions every year on a range of issues... -
CRISPR 101: RNA Editing with Cas13
TypeBlog Post...minimize local off-target editing by RESCUE. To address both C-to-U and A-to-I transcriptome-wide off target...off-target A-to-I edies by ~94% compared to RESCUE. Addressing the potential use of RESCUE in therapeutic applications... -
SciComm: Taking Science to Elementary and Middle Schools
TypeBlog Post...community as a scientist. Perhaps you have young children and you want to make sure their STEM education...regardless of race or ethnicity. Perhaps you don’t have children but are interested in testing your SciComm skills... -
An Introduction to Adenovirus
TypeBlog Post...three (Servellita et al., 2023). Normally when children have acute viral hepatitis it is caused by the...Y. (2023). Adeno-associated virus type 2 in US children with acute severe hepatitis. Nature, 617(7961)... -
CRISPR Between the Genes: How to Experiment with Enhancers and Epigenomics
TypeBlog Post...Google Maps to help us identify and visualize addresses. That’s where enhancers and genome math come in...how genome math helps us to locate interesting addresses in the genome. Let’s now examine how we can locate... -
The Importance of a Fun Workplace: Company Culture at Addgene
TypeBlog Post...remaining time by elaborately pranking each other, dressing in costume, and holding competitions (ranging ... of fifty instead of three, and we are sending hundreds of plasmid requests out each day. As you may imagine... -
Negotiating Work and Life: How to Find the Joy
TypeBlog Post... yourself, “I’m not married,” or “I don’t have children, so my life will be under control.” Think again...starve while you are away a few days. Also, your children will enjoy day care and school if you tell them... -
Bioinformatics at Addgene
TypeBlog Post... between Seqera’s mission and our own, as both address the need to accelerate science using different ...necessary to keep up with our sequencing instrument (hundreds of plasmids each week!), we already planned to... -
To Codon Optimize or Not: That is the Question
TypeBlog Post...gene which could affect translation initiation (Dresios et al., 2006) and mRNA stability (Hausser et al...18: . https://doi.org/10.1186/s12859-017-1793-7 Dresios J, Chappell SA, Zhou W, Mauro VP (2005) An mRNA-rRNA... -
New Tools Enable CRISPRa for Neuroscience Applications
TypeBlog Post...expression in the central nervous system (CNS). To address this technological gap, a trio of recent papers...isoform-specific expression of Bdnf resulted in hundreds of differentially expressed genes between Bdnf...