We narrowed to 997 results for: lars

...Publication Return to top CRISPR Resources Addgene has a large selection of CRISPR plasmids and resources. Find...

...Proteins: Empty Backbones Fluorescent Proteins: Subcellular Localization Luciferase Plasmid Collection Viral...

... Addgene for distribution. Look up the IDs of particular Penn Vector Core catalog items. Virus-associated...

...Screening Surface Display cDNA Depositor Collections A modular set of plasmids from a depositor organized by a...

...robust, noiseless knockdown of bacterial genes. Molecular Systems Biology, 14(3):e7899. doi: 10.15252/msb...

...Resources Solute carrier proteins (SLCs) are the largest family of transporters in the human genome with...

...Publication Return to top CRISPR Resources Addgene has a large selection of CRISPR plasmids and resources. Find...

...performance of various serotypes before conducting larger scale experiments. For more information, see our...

... some cases, we may expect lower titers for a particular AAV prep, mostly likely due to one of the following...

... OPEN OPEN cCGCTTCAGCggtctGTGGACTCGa zebrafish similar to grp151 (or gpcr-2037) OZ535 and OZ536 OPEN OPEN...

...Welker Return to top CRISPR Resources Addgene has a large selection of CRISPR plasmids and resources. Find...

...expression of fluorescent TAL effectors to visualize subcellular positioning of target DNA sequences in living...

...Bonaguro, R. J., Brauer, E., Candido, T. R., Castellarin, M., Chen, J., Chen, Y., Cheng, J. C., Chopra...

...within academia, most particularly postdocs working in the U.S., whose current salaries are below the new ...proposed raising the salary for exemption to $50,440 and also suggested that the salary level should now ...gauge exactly how postdoctoral salaries are changing. Transparent salary information for postdoctoral positions...get paid. Institutional salary policies are one indicatator of how salaries may changes due to the FLSA...had a minimum salary policy: of those, 51% of institutions set their postdoctoral salary scales to the...different points on this salary range. We have been able to gather data on changes to salary for some of the institutions...2015, Stanford raised salary levels to $50,000, and as of October 1st the salary minimum was raised again...

...from their increased salaries. In addition, salary uncertainty may be particularly problematic for two-...were expected to receive salary raises, 6% of postdocs were to have either salaries raised or hours tracked...plans to raise salaries. What are institutions doing after the injunction? We are particularly interested ...requests for their postdoctoral salary information as of December 1st. Salary inconsistencies across geographical...than 40 hours per week could expect to see their salary raised to at least a new legal minimum of $47,476...(FLSA). This was due to the threshold at which salaried workers receive overtime payment for working more...affecting universities' decisions to alter postdoc salaries - in some cases reversing these decisions entirely...

...Understanding intracellular pH regulation is important as pH regulation has roles in many cellular functions... for monitoring cellular dynamics. These fusion proteins have been used as subcellular markers to visualize...Rtn4a-GFP (tubular ER) Microtubules mCherry-alpha-tubulin Early Endosome Vacuolar Compartment...context, they should be expressed at similar levels and under similar conditions as their wild-type counterparts...SunTag system. The SunTag system, named after the "stellar explosion SUperNova", is a synthetic scaffold that...thereby creating a single-molecule reporter of intracellular processes. Multimerization via the SunTag system...available through Addgene and are already very popular. Use these plasmids to increase the brilliance ...

...pH-insensitive, while SEP fluoresces at cellular pH (7.0) but not at vacuolar pH (6.2). The colour of Rosella ...highlight the main features and applications of a partiular plasmid or set of plasmids. We hope that these...Stark and colleagues at the Research Institute of Molecular Pathology have developed an alternative method...altering gene expression are relatively well known, particularly in bacteria, the process of cloning, combining... Integration of Design Automation Research lab Moduclar Cloning (CIDAR MoClo) Parts Kit. This Kit consists...involved in cell signaling pathways that control many cellular processes such as differentiation, proliferation...cloning platform called GMAP (Gibson assembly-based modular assembly platform). GMAP is based on the Gibson...

...director of the MSOE center for BioMolecular Modeling and the CEO of 3-D Molecular Designs. Have you ever held...of a protein. The Bender’s popularity was short-lived as powerful molecular graphics packages were soon...educators and students use molecular models?   We created the Center for BioMolecular Modeling (CBM) in 1999... Center for BioMolecular Modeling, we spun off a small, family-run business – 3D Molecular Designs – to...director of the MSOE center for BioMolecular Modeling and the CEO of 3-D Molecular Designs.     Additional Resources... of your favorite protein in your hand? At 3D Molecular Designs, we create physical models of proteins...the models we create are around 30 million times larger than the real thing. Nevertheless, the models are...

...receptors (GPCR) regulate cellular function through multiple intra-cellular signaling cascades. Optical... in the extracellular domain which activates the native signaling cascade of the intracellular part of...have developed many optogenetic tools to control cellular activity with exquisite precision using only light...expressing the optogenetic tool causing a change in cellular activity or gene expression. Experimental output...both the membrane potential and a host of other cellular functions. Photoswitches are engineered molecules...enter the cell with the concentration gradient to depolarize it (Nagel et al., 2003). Inhibitory opsins are...Na+) against the concentration gradient and hyperpolarize the cell (Mattis et al., 2012). Bicistronic ...

...astrocytes and neurons and the molecular foundations of their multicellular interactions. Neuron, 113(16...Micropeptide killswitch for biomolecular condensates By Emily P. Bentley Biomolecular condensates are membraneless...discovered that disruption of the nucleolus — the largest biomolecular condensate in human cells — causes a rare...peptide that caused nucleolar disruption into a general "killswitch" for other biomolecular condensates (Zhang...PinkyCaMP and FRCaMPi Micropeptide killswitch for biomolecular condensates AAV-CRISPRa-engineered fat cells...proteomes (Wu et al., 2025). The team expressed extracellularly-anchored horseradish peroxidase (HRP) in striatal...of astrocytes and neurons (CS SPAN) featured extracellular matrix proteins, cell adhesion molecules, transporters...