We narrowed to 961 results for: ARC
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TypeBlog Post... A recent survey of PhDs found that many researchers feel that they lack formal training in a variety...out to fill this gap by both highlighting that researchers do learn MANY transferable skills while working...
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Truncated gRNAs for Regulating Gene Expression
TypeBlog Post...bloggers Alissa Lance-Byrne and Alex Chavez, researchers at the Wyss Institute for Biologically Inspired...University of California, Santa Cruz, where her research is focused on engineering nanoparticles as drug... -
Plasmids 101: Knockout/Knock-In Plasmids
TypeBlog Post...resistance gene can affect a cell's phenotype, researchers usually remove it after selection using the Cre...conditional knockout. To make a conditional knockout, researchers often use the Cre/Lox system described earlier... -
PCR Applications for Copy Number Variation Assays
TypeBlog Post... of a gene exists, there must be assays that researchers can use to quantify said copies. They do so using...commonly available and may not be an option to all researchers. Accuracy needed Do you need to call exact... -
Transferable Skills: Negotiation
TypeBlog Post...A 2017 survey found that many researchers feel they lack formal training in a variety of transferable...set out to fill this gap by highlighting that researchers learn many transferable skills while working ... -
Degrading DNA with Cascade-Cas3
TypeBlog Post...of CRISPR-based immune systems in bacteria and archaea. Class 1 is further broken down into different ...ubiquitous in nature, they are largely underutilized in research settings — mostly a consequence of Cascade's complexity... -
The AAVantages of AAV in CRISPR Screens
TypeBlog Post...from one serotype and the capsid of another. Researchers have used these psuedotypes to further improve...-022-00700-y Hanlon, K. S., Kleinstiver, B. P., Garcia, S. P., Zaborowski, M. P., Volak, A., Spirig, S... -
PRIDICT: Predicting Efficiencies of Prime Editing Guide RNAs
TypeBlog Post...recent studies (Mathis et al., 2024) and concurrent research by the Shendure lab (Li et al., 2024) have highlighted...Newby, G. A., Raguram, A., & Liu, D. R. (2019). Search-and-replace genome editing without double-strand... -
Multiplexed Capture of Promoter-enhancer 3D Chromatin Structures Using CRISPR
TypeBlog Post...on-target enrichment. 2. Determining the spatial and hierarchical organization of chromatin interaction networks...CAPTURE 2.0 is the construction of spatial and hierarchical chromatin interaction networks. Think of these... -
Antibodies 101: Flow Compensation
TypeBlog Post...has a research background in CD8+ T cells and cancer immunotherapies. She is currently a research technician...