We narrowed to 955 results for: ARC;
-
TypeBlog Post... A recent survey of PhDs found that many researchers feel that they lack formal training in a variety...out to fill this gap by both highlighting that researchers do learn MANY transferable skills while working...
-
Truncated gRNAs for Regulating Gene Expression
TypeBlog Post...bloggers Alissa Lance-Byrne and Alex Chavez, researchers at the Wyss Institute for Biologically Inspired...University of California, Santa Cruz, where her research is focused on engineering nanoparticles as drug... -
Plasmids 101: Knockout/Knock-In Plasmids
TypeBlog Post...resistance gene can affect a cell's phenotype, researchers usually remove it after selection using the Cre...conditional knockout. To make a conditional knockout, researchers often use the Cre/Lox system described earlier... -
Degrading DNA with Cascade-Cas3
TypeBlog Post...of CRISPR-based immune systems in bacteria and archaea. Class 1 is further broken down into different ...ubiquitous in nature, they are largely underutilized in research settings — mostly a consequence of Cascade's complexity... -
The AAVantages of AAV in CRISPR Screens
TypeBlog Post...from one serotype and the capsid of another. Researchers have used these psuedotypes to further improve...-022-00700-y Hanlon, K. S., Kleinstiver, B. P., Garcia, S. P., Zaborowski, M. P., Volak, A., Spirig, S... -
PRIDICT: Predicting Efficiencies of Prime Editing Guide RNAs
TypeBlog Post...recent studies (Mathis et al., 2024) and concurrent research by the Shendure lab (Li et al., 2024) have highlighted...Newby, G. A., Raguram, A., & Liu, D. R. (2019). Search-and-replace genome editing without double-strand... -
Antibodies 101: Flow Compensation
TypeBlog Post...has a research background in CD8+ T cells and cancer immunotherapies. She is currently a research technician... -
Plasmids 101: Optimizing Plasmid Yields
TypeBlog Post...This post was updated on March 21, 2018. Most of the time, plasmid prepping is a breeze. You get your...copy number of the empty plasmid backbone or a researcher’s personal observations. If you are experiencing... -
PITChing MMEJ as an Alternative Route for Gene Editing
TypeBlog Post...If you follow CRISPR research, you know all about using non-homologous end-joining (NHEJ) to make deletions...al.’s use of MMEJ represents another strategy researchers can exploit for CRISPR gene editing. In organisms... -
CRISPR 101: Mammalian Expression Systems and Delivery Methods
TypeBlog Post...Last updated Sep 30, 2020 by Marcy Patrick. CRISPR technology has been widely adopted for genome editing...McDade for creating the Expression Systems table. Marcy Patrick contributed to the writing of this post....