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Showing: 751 - 760 of 1073 results
  1. Addgene's a Nonprofit? Nonprofit Awareness Day 2017

    Type
    Blog Post
    ...individuals through stock or investor pay outs. Addgene has no investors or stock. All of our proceeds...proceeds go into running the repository and serving scientists better. That includes keeping fees as low as ...
  2. Fluorescent Proteins 101: Fluorescent Biosensors

    Type
    Blog Post
    ...biological sensors’) are biological tools that monitor a process or detect a given molecule. The sensor...in. Depending on the process you would like to monitor, there may be multiple steps you could examine,...biosensors. These constructs are often used to monitor enzymatic activity or phosphorylation over time...
  3. We're Updating Our Hold for Publication Policy

    Type
    Blog Post
    ...original policy was straightforward, but cumbersome: depositors had to email us with permission to release their... are left in the hold status and reach out to depositors about them, but we all know how easy it is to...your work. Plus, it’s costly for us to process and store materials that aren’t distributed or for our teams...
  4. CASTing Off for New Shores in Human Genome Editing

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    Blog Post
    ...affiliated TniQ protein recruits transposition cofactors. The transposon proteins integrate a payload sequence... Figure 1: Mechanism of CAST systems. A Cas effector (Cascade in Type I systems; Cas12k in Type V-K...Programmable gene insertion in human cells with a laboratory-evolved CRISPR-associated transposase. Science...
  5. An Addgene Summer Internship

    Type
    Blog Post
    ... gene in a pLenti vector backbone. During those five weeks, I worked with my mentors, Katherine, Amrita...exchanged contact with Amy C., Addgene’s intern coordinator shortly after hearing her talk about Addgene’...
  6. Zebrafish as a Model for Behavior: Swimming into the Optogenetic Spotlight

    Type
    Blog Post
    ...neurons that trigger the CPG (central pattern generator) (Wyart et al., 2009). The CPG is a neural circuit... involved in locomotion that generates periodic motor commands for rhythmic movements like spontaneous...optogenetics blog posts Read blog posts about viral vectors Subscribe to the Addgene blog Resources on Addgene.org...
  7. Build Your CRISPR Vocabulary

    Type
    Blog Post
    ...used to target complementary DNA sequences. In laboratory settings, an sgRNA includes the crRNA and tracrRNA...array: The section of the bacterial chromosome that stores a genetic record of previously encountered foreign...itself, simplifying the CRISPR-Cas9 system for laboratory applications. At Addgene, we sometimes refer ...
  8. Running for Rare Disease, Running for FOP, Running for AJ

    Type
    Blog Post
    ...patient partners so that they can help tell their stories. I was paired with a six-year-old boy named AJ ...caused by a single R206H point mutation on the receptor ACVR1. ACVR1 triggers appropriate bone regeneration...where my wife Lianna has made her career as Senior Director of Biology, is helping us fight against FOP in...
Showing: 751 - 760 of 1073 results