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Showing: 141 - 160 of 913 results
  1. NETRF

    Type
    Collection
    ...treatment of neuroendocrine cancers. As such, NETRF strongly encourages its funded scientists to make their...
  2. TALEN Expression Vectors

    Type
    Collection
    ...mammalian cell expression and a T7 promoter for in vitro transcription of RNA. TALENs expressed from these...
  3. Fluorescent Protein Guide

    Type
    Collection
    ...Plasmids | Guide Use light to detect, measure, and control molecular signals, cells, or groups of cells with...
  4. All Antibodies

    Type
    Collection
    ...undergo application-specific validation and quality control by Addgene as well as by our trusted partner labs...
  5. Plasmid Collections

    Type
    Collection
    ...Plasmids Lentivirus Adeno-associated Virus (AAV) γ-Retrovirus Adenovirus All Viral Plasmids Curated Topics ...
  6. Chemogenetics Plasmids

    Type
    Collection
    ...specific small molecules, allowing a scientist to control signaling within cells expressing these engineered...
  7. Antibody Plasmid Collection

    Type
    Collection
    ...undergo application-specific validation and quality control by Addgene as well as by our trusted partner labs...
  8. CRISPR Plasmids - Prime Edit

    Type
    Collection
    ...enzymes and related tools are available: PE2 - introduction of five mutations in RT enzyme PE3 - PE2 plus...
  9. Arf GTPase Family

    Type
    Collection
    ...traffic, they also play critical roles at cilia, centrosomes, the plasma membrane, lipid droplets, the nucleus...
  10. Kazuhiro Oka Lentiviral Vectors

    Type
    Collection
    ...vectors to express your gene of interest under the control of a variety of promoters. Professor Oka and the...
  11. TALEN Guide

    Type
    Collection
    ...new technology, and we hope to continue to have a strong scientific partnership with both the labs that ...
  12. CRISPR Plasmids - Tagging

    Type
    Collection
    ...Yannick Doyon's lab deposited a plasmid which introduces an N- or C- terminal affinity tag (3xFLAG-2xSTREP...
  13. Viral Vectors 101: Systemic Capsids

    Type
    Blog Post
    ...specificity, or retrograde transport in neurons. (b) Genetic cargo can be customized to control transgene expression... Capsid Published Tropism Model Organism Mouse Strain-Specific Tropism?  Reference AAV-...and astrocytes Mice No (LY6C1)   Hanlon et al., 2019 AAV-BI-28 CNS: neurons, astrocytes, oligodendrocytes...-Specific Tropism?" column. For a complete list of mice strains with LY6A-dependent tropism, see S3 table...derived from AAV9 using iTransduce, shows tropism toward astrocytes and neurons, with greatly increased efficacy... appears to show a broader tropism with a potential bias toward astrocytes (Chuapoco et al., 2023). Additionally...systemic AAVs with endothelial-specific tropism in rodents and broad tropism in primates. Nature Communications...
  14. Using AAV for Neuronal Tracing

    Type
    Blog Post
    ...developed a new AAV variant, rAAV2-retro, that migrates retrogradely at higher rates than any other AAV... AAV2-retro vectors with a variety of transgene/promoter combinations. Check out our retrograde AAV blog...requires both antero- and retrograde labelling, synaptic restriction as well as controlled monosynaptic and polysynaptic...Selective retrograde transsynaptic transfer of a protein, tetanus toxin, subsequent to its retrograde axonal...bodies to the terminals of their axons; while retrograde tracing outlines neurons in the opposite direction...axons to their cell bodies. Anterograde and retrograde tracing take advantage of existing transport ...myosin, and enzymes for transmitter synthesis. Retrograde transport is used for transport of endocytosed...
Showing: 141 - 160 of 913 results