Skip to main content
Addgene

Enter a sequence to perform a BLAST-based search of Addgene plasmid sequence databases.

In Category

We narrowed to 962 results for: ARC

Showing: 941 - 950 of 962 results

  4. CRISPR/Cas9 FAQs Answered!

    Type
    Blog Post
    ...and their applications can be exhausting. A quick search for "CRISPR", short-hand for Clustered Regularly...

  6. Optogenetics Guide

    Type
    Guide
    ...Example: ArchT Increased photocurrent amplitude Examples: eArch3.0, eArchT3.0 Browse Archaerhodopsin plasmids...Browse Halorhodopsin plasmids . Archaerhodopsins Archaerhodopsin-3 (Arch) from Halorubrum sodomense is ...589 Archaerhodopsins Arch Light-activated outward proton pump from Halorubrum sodomense 566 eArch 3.0 ...TP009. Improved light sensitivity over Arch. 566 eArchT 3.0 ArchT with addition of trafficking signal from...cell when triggered by green-yellow light. Arch Variants. Arch variants have been developed with the following...3.0 Arch with addition of trafficking signal from Kir2.1 566 ArchT Light-activated outward proton pump from...tools and technologies developed for optogenetics research utilize light to detect, measure, and control ...

  7. CRISPR Guide

    Type
    Guide
    ... help you get started using CRISPR in your own research. CRISPR Basics In this section, we will introduce...same chromosome. Most multiplex systems enable researchers to target anywhere from 2–7 genetic loci by cloning...later in the guide. Increasing fidelity of Cas9 Researchers have also enhanced specificity by engineering... overcome the CRISPR systems that bacteria and archaea use to protect against these foreign nucleic acids...Base Editing To overcome low HDR efficiency, researchers have developed base editors to specifically convert...Figure 5: Overview of base editing More recently, researchers have developed base editors that can catalyze...Base Edit CRISPR Prime Editing Prime editing is a “search and replace” gene editing method in which Moloney...

  8. Lentiviral Vector Guide

    Type
    Guide
    ...conducting cellular barcoding experiments. Lentiviral vectors allow for integration of the barcodes, which can ...treatments into cells, and has been widely used in the research community for decades. Wild-type lentiviruses ...vectors have many aspects that make them useful research tools in a variety of cell types and models. Lentiviral... of a transgene, lentiviral vectors are useful research and clinical tools. Stable Cell Lines Lentiviral...Addgene's collection of CRISPR libraries . Cellular Barcoding Much like genomic screens, lentiviral vectors ...inherited by daughter cells. Inheritance of the barcodes makes lentiviral libraries popular for lineage...heterogeneous tumors. Browse Addgene's collection of barcoding libraries . Mouse Modeling Since the development...

  9. Adenovirus Guide

    Type
    Guide
    ...Wild-type adenoviruses have been modified by researchers to create recombinant adenoviral (rAdV) vectors...gene expression patterns that were observed, researchers have tended to favor using first- and third-generation...is still the most commonly used generation for research purposes. The system consists of two plasmids ...in combination with foreign capsid proteins. Researchers have further refined the tropism of rAdV vectors...vectors are often the preferred choice among researchers due to their reduced immunogenicity and longer...transgene expression, rAdV vectors are used in many research fields, especially when needing transgenes to ... and can trigger a strong immune response to researchers if exposed. There is a risk of spontaneous reversion...

  10. Adeno-associated virus (AAV) Guide

    Type
    Guide
    ...Vectors Wild-type AAVs have been modified by researchers to create recombinant adeno-associated viral ...in combination with foreign capsid proteins. Researchers have further refined the tropism of rAAV vectors...diffused biological structures. Specifically, researchers were interested in creating systemic capsids ...send information to a given region. This allows researchers to trace connections between neurons, map the...make them ideal for gene therapy, neuroscience research, and other biomedical fields. Gene Therapy One... opsins and other optical tools developed by researchers are used to detect, measure, and control molecular...institution's best practices with regard to AAV-related research. See Addgene’s Biosafety Resource Guide for more...
Showing: 941 - 950 of 962 results