We narrowed to 17 results for: SAM activators

Choosing a CRISPR activator? This article features four of the most popular CRISPR activators (dCas9-VP64, SAM, SunTag, and VPR) and some newer activators like dCas9-CBP and SPH.

Scientists are currently developing disease treatments using CRISPR. Learn about recent developments in the fight against HIV-1 with CRISPR.

New CRISPR pooled libraries, such as SAM, CRISPRa, and CRISPRi, offer new ways to do genome-wide functional screens.

CRISPR Cas9 gRNA plasmids from the Zhang lab

Discover the best situations to use Cas9 activators in your experiments with tips from their creators.

A review of protein expression mechanisms for on, off, and tunable, control of protein expression.

The labs of John Doench and David Root have recently created CRISPR libraries to knock out, inactivate, or activate genes for genome-wide screens. These optimized libraries are effective for probing gene function while using fewer sgRNAs.

Learn about the latest CRISPR plasmids deposited at Addgene, including a miniature CRISPR-Cas systems, SEND plasmids, and prime editing improvements

Learn how to plan a basic CRISPR experiment, including selecting the edit type, designing and cloning a gRNA, delivering Cas and the gRNA, and validating the edit.

With many different Cas9 variants out there, it can be hard to know which one to use in your particular CRISPR experiment. This post is here to help.

Did you know CRISPR can be used to target non-coding RNAs? In this blog post, we explain the pros and cons of different approaches.

Explore Addgene's collection of luciferase plasmids for gene expression assays and bioluminescent reporters.

Addgene's guide to using CRISPR plasmids in your lab, from knockouts to pooled library screening.

Learn how to plan a basic CRISPR experiment, including selecting the edit type, designing and cloning a gRNA, delivering Cas and the gRNA, and validating the edit.

Addgene's guide to using CRISPR plasmids in your lab, from knockouts to pooled library screening.

Addgene’s immunology collection contains plasmids for genes involved in innate and adaptive immune signaling and cell-cell communication.

Addgene's guide to using Chemogenetics plasmids in your lab for interrogation of neuronal activity.