We narrowed to 630 results for: Son
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TypeBlog PostPublishedDec. 2, 2016, 3:30 p.m.
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A Control for All Seasons
TypeBlog PostPublishedOct. 5, 2023, 1:15 p.m. -
Plasmids 101: Using Transposons in the Lab
TypeBlog PostPublishedJuly 6, 2021, 1:28 p.m....eukaryotic genomes. Components of a transposon system Transposon: The transposon is the DNA sequence that moves...also called retrotransposons, and Class II TEs, also called DNA transposons. DNA transposons are commonly...discovered transposons due to changes in coloration of corn kernels. Aside from corn, transposons are in ...2010). So why do transposons matter? The outcome really depends on where a transposon lands. For example...components of transposons, how they are classified, and how they are used in the lab. What is a transposon? DNA...Transposable elements (TEs): Retrotransposons Class I TEs are also known as retrotransposons. They transpose by...which are required for LTR retrotransposon transposition. Non-LTR retrotransposons contain two open reading... -
Deep Dive: Statistical Tests (Comparisons)
TypeBlog PostPublishedMarch 7, 2023, 2:15 p.m....tests. All sample comparisons Do you really need to know every pairwise comparison within your population...we will dive into the nitty gritty details of comparison statistical tests – when to use them, what they...one-tailed test also works for exclusively less-than comparisons. Paired and unpaired t-tests Samples that come...family-wise error rate by only performing the comparisons you really care about. Family-wise error is the...probability of a false positive occurring when many comparisons are performed. For example, if your alpha is ...you have 5 samples and perform every pairwise comparison (10 in total), your likelihood of a false positive...higher than if you only look at 2 or 3 pairwise comparisons. Similar to family-wise error, is the false discovery... -
5 Reasons to Use Reddit for Science Communication
TypeBlog PostPublishedOct. 20, 2016, 2:30 p.m....do an AMA in the first place and give you some reasons why you should consider using Reddit to share your... as our first foray into Reddit. Here are some reasons why: 1. Reddit has a large and active community... -
Cpf1 Update: Comparison to Cas9 and NgAgo
TypeBlog PostPublishedJuly 14, 2016, 2:30 p.m. -
The Many Reasons for Irreproducible Research- and a Vaccine to Eradicate It
TypeBlog PostPublishedJan. 30, 2020, 2:15 p.m....research findings so difficult to do? There are four reasons that research can be difficult to replicate. Unclear...with powerful cognitive biases such as motivated reasoning and hindsight bias, we may fool ourselves and ...Unanticipated discoveries Finally, there are good reasons for obtaining a different result after conducting... -
Networking Follow-up: I Met a Person. Now What?
TypeBlog PostPublishedJan. 12, 2021, 2:15 p.m....contact to connect on LinkedIn and always include a personal note about where you met and what you discussed...the near future. Even just one more meeting (in person or virtually) will make the relationship stronger... law of networking--don’t be creepy. There is a person on LinkedIn I once helped by answering one simple...not at all necessary. Once you’ve talked with a person a few times, if it was a positive experience for...was in graduate school, there was only one other person in my class who had children. When I had my baby...answered my questions and honestly, she was the only person who really understood what I was going through.... -
Reproducibility for Everyone: Lessons from an Open Science Collaboration
TypeBlog PostPublishedFeb. 28, 2019, 1:34 p.m....conversations on the history of the group, lessons learned, and to Sonali Roy, Magdalena Julkowska, and Jennifer... provide greater visibility of these materials, Sonali Roy, a postdoctoral researcher at the Noble Research...effort. The future of reproducibility workshops and lessons learned: Since early 2018 the team has grown to...researchers at all levels of the scientific community. Lessons learned Instead of continuously talking about... -
INTEGRATE: Bacterial Genome Engineering Using CRISPR-Transposons
TypeBlog PostPublishedDec. 7, 2020, 2:53 p.m....Zhang group. Mechanism of CRISPR-transposons One of the CRISPR-transposon systems developed by the Sternberg...aka mini-transposon), which contains the DNA cargo of interest flanked by ~50-150 bp transposon end sequences...characteristic of the Tn7-family of transposons. Insertion of the mini-transposon can occur in two different orientations...with the same transposon exhibit reduced efficiencies (Vo et al., 2020). CRISPR-transposons within the CRISPR...Lab at Columbia University Medical Center. DNA transposons are ubiquitous genetic elements capable of spreading... Beauty). Despite their diverse utility, DNA transposons have been hindered by their limited programmability...recently surpassed with the discovery of CRISPR-transposons by the Sternberg and Zhang labs (Peters et al...