We narrowed to 546 results for: TIL;

...PRESTO-TANGO: The ligands that activate many GPCRs are still unknown. To identify some of these unknown ligands...adrenoceptor. GPCRs in chemogenetics  While there’s still a lot to learn about GPCR signaling, researchers...

...the surface of the bead, suggesting that OptoNBs still bound their target protein even when stuck to the...This signaling is a lot like a game of telephone, until the message reaches the nucleus where gene expression...

...one is not available, don’t lose hope! It could still work. Take a close look at the antigen or antigenic... through the above steps, you may find that you still have a number of options. If this is the case, you...

...improvements Miniature CRISPR-Cas systems By Brook Pyhtila One drawback to the commonly used S. pyogenes CRISPR...describes an effective miniature Cas system that utilizes a Cas12f from a different species, Acidibacillus...

...The titer is tested following each immunization until the desired level of antibodies is reached - typically...increases the likelihood that one of the clones will still recognize your protein. For the same reason, they...

...immunohistochemistry techniques. Thus, these proteins provide a versatile method to identify the expression of transgenes...the membrane in mice neurons, most of them were still cytoplasmic. Use of ‘small’ tags to identify proteins...

...-36 receptor inhibitors in development, there’s still a lot of mysteries surrounding IL-36 biology. “Little...To study cellular transduction events, we will utilize BRET-, FRET-, and intensity-based signaling biosensors...

...all of us played with LEGO as a child (some of us still do), so we are used to the idea of general interfaces...of Click Biology is made possible through the utilization and development of genetically engineered components...

... additional chemicals or modifications. This versatility opens up the potential for spatial and temporal...are more evenly controlled. The Grefen Lab has utilized the 2in1 cloning system to generate a series of...

...science, but also science writing.  “And since I was still in grad school, I had the opportunity to take a ... Susan personally found this easier to do while still in school since opportunities, such as writing for...

...environment” with a strong focus on publishing, but still made it so she could “get exposure to the drug discovery...and Wood Drug Screening Kit Find Out How to Best Utilize Our Cancer Resource Pages  Resources at Addgene...

...administration information. Carefully read over all parts until all aspects are understood. While reading the funding...research project grant application" by the NIH Still want more information on the application process...

... that is useful, but not 100% complete, we will still make this data available as a partial sequence with...Harten DeMaio K, Sanders E, Tasissa M, Kostman M, Tillgren M, Makana Hanley L, Mueller I, Mitsopoulos A, ...

... to modify chromatin. A fluorescent protein can still be included for visualization purposes, but the ...gRNA complex binds the target DNA without cleavage until it's activated by light. Once activated, Cas9 cleavage...

...proteins. Discovery of anti-CRISPR proteins That is, until the discovery of anti-CRISPR proteins in 2012 (Bondy-Denomy... RNPs, AcrIIA4 reduced off-target editing while still allowing on-target editing (Shin et al., 2017). ...

...make sure yours counts. Dress professionally but still like yourself. It’s better to be overdressed rather...challenges, your interviewers might.  You’ll probably still be required to give a job talk for a remote interview...

...to both people and the tools we use. Scientists utilize an array of tools that rely on DNA amplification...reference is given, de novo assembly in Geneious can still provide additional insights to resolve the assembly...

...harsher stripping means more sample loss. If you are still optimizing your system, start with a mild stripping...always be added fresh to solutions. It is also volatile and toxic (and smells bad!), so be sure to use...

...include embryonic lethality, a short lifespan, or infertility and can arise due to copy number, expression ...would get both mutations onto the same chromosome. Until crossing over occurs between the two loci, F2 and...

...large tags into a precise location in the genome is still inefficient, particularly in human cell lines. Furthermore...large regions of homology enable us to effectively utilize the host cell’s inherent homology directed repair...