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  1. Download Science-Themed Zoom Backgrounds from Addgene

    Type
    Blog Post
    Published
    April 22, 2021, 1:15 p.m.
    ... Zoom’s default backgrounds all year and want a change? Addgene has you covered. Today we’re releasing...next meeting.     If you’re reading this blog, chances are you are a fan of Addgene or our very cute mascots...

  3. How Exercise Purges Stress and Keeps Depression at Bay

    Type
    Blog Post
    Published
    Nov. 25, 2014, 4:02 p.m.
    ...depression, and now researchers have reported a mechanism based on studies of transgenic mice that helps...brain is protected from stress-induced biochemical changes that could otherwise lead to depression. And there...

  4. A Conference By Postdocs For Postdocs: Future of Research

    Type
    Blog Post
    Published
    Sept. 2, 2014, 3:05 p.m.
    ...must do science to be happy. What do we have to change to ensure that all scientists can have successful...training too many scientists and some propose radical changes to the way we view the graduate school and postdoc...

  5. Keeping Up With CRISPR/Cas9

    Type
    Blog Post
    Published
    March 11, 2014, 5:55 p.m.
    ...Scientists at North Carolina State, in the labs of Chase L. Beisel and Rodolphe Barrangou, had applied the...Powerful New Way to Edit DNA" and "This Protein Could Change Biotech Forever."  David S. Weiss of Emory University...

  6. Addgene's Top Blog Posts from 2020

    Type
    Blog Post
    Published
    Dec. 29, 2020, 2:15 p.m.
    ...many molecular biology methods such as allelic exchange, FRET, and synthetic biology. 7. 25 Work From...them in the cell. This blog post features two mechanisms that cause plasmids to be incompatible. 4. RNA...

  7. Science Communication for Everyone

    Type
    Blog Post
    Published
    April 16, 2019, 1:05 p.m.
    ...by scientists, which is hosted on our Instagram channel every Sunday. What's planned for the upcoming year...while “manipulate” could mean “worked with” or “changed” to scientists. Keep your message to the main three...

  8. Microbes: Look, Listen, and Tell

    Type
    Blog Post
    Published
    Aug. 28, 2018, 12:04 p.m.
    ...conference, you may think about sitting amongst a sea of chairs listening to talks all day. But nope, not at the...makes scientific topics both interesting and approachable!   The grand finale of visual impressions was...

  9. Bringing Sustainable Practices to the Lab: Innovations

    Type
    Blog Post
    Published
    March 7, 2019, 2:39 p.m.
    ...variety of pipette tips. This is part of a cultural change in how we approach waste that needs to be supported...for things like truck bumpers, plastic adirondack chairs, and synthetic turf. I was truly amazed by this...

  10. Scientist Networking: What is an Informational Interview?

    Type
    Blog Post
    Published
    July 1, 2014, 3:42 p.m.
    ... about salary, opportunities for advancement, challenges and disappointments. These more personal questions...people honor. Talking with strangers is usually challenging but does get easier with practice. Another perk...

  11. Top 10 Open Science Developments of 2013

    Type
    Blog Post
    Published
    Dec. 19, 2013, 3:46 p.m.
    ...      In June, the White House honored 13 “Champions of Change,” including our recent guest Drew Endy, in...

  13. Six Spooky Science Stories and Halloween at Addgene

    Type
    Blog Post
    Published
    Oct. 31, 2019, 1:06 p.m.
    ...gills. It attaches there until they mature and changes sex from male to female. Then, it detaches from...16191624. PubMed Central PMCID: PMC1559948. Brusca, Richard C., and Matthew R. Gilligan. "Tongue replacement...

  14. X-CHIME: Context Dependent Germline Knockout in Immune Cells

    Type
    Blog Post
    Published
    Jan. 16, 2024, 6:13 p.m.
    ...knockout mice, which is time-consuming, as it only changes one gene at a time. CRISPR-based systems enable...power of these systems to investigate in vivo mechanisms, we targeted two phosphatases, PTPN1 and PTPN2...

  15. Tag Your Favorite Yeast Genes with Ease

    Type
    Blog Post
    Published
    Nov. 19, 2013, 2:37 p.m.
    ...yeast developed by Dr. Pringle’s former lab at UNC Chapel Hill. Bähler et al.(2) describe a modular collection... McKenzie A 3rd, Demarini DJ, Shah NG, Wach A, Brachat A, Philippsen P, Pringle JR. Yeast. 1998 Jul;14...

  16. Addgene is Expanding Our Viral Vector Service!

    Type
    Blog Post
    Published
    Oct. 15, 2024, 1:15 p.m.
    ...and you will be notified via email. There is no charge for the request process.  Ordering If your request...until you have placed your order. You will only be charged once you have added the prep to your cart and checked...

  17. Scientific Sharing in the Time of COVID-19: Databases and Resources

    Type
    Blog Post
    Published
    May 12, 2020, 1:15 p.m.
    ...otherwise not be able to work on through normal mechanisms. It will take the full breadth of our research...comprehensive list). #coronavirus #SARSCoV2 #Covid19researchA thread ⬇️⬇️⬇️ — Addgene (@Addgene) April 15...

  18. What's New in CRISPR - March 2020

    Type
    Blog Post
    Published
    March 10, 2020, 1:15 p.m.
    ...that controls repression of gene expression in Saccharomyces cerevisiae. The system consists of dCas9, the...several weeks to delete or deplete individual genes. Michael Laub’s lab developed a CRISPRi system to downregulate...

  19. Same Addgene, New Look - Why We Redesigned Our Homepage & Mascot

    Type
    Blog Post
    Published
    Dec. 5, 2019, 1:49 p.m.
    ...homepage recently, you probably noticed some big changes to our site (if you haven’t, go check it out!)....happy and inspired to tackle your next science challenge. If you have any feedback, please contact us and...

  20. Supporting Rare Disease Research with BeHeard 2017

    Type
    Blog Post
    Published
    July 20, 2017, 2:30 p.m.
    ... cause spinal muscular atrophy, the molecular mechanisms behind the disease are unclear. Dr. Di Schiavi... Dr. Di Schiavi will use Addgene plasmids to characterize smn1 interactions with other genes. He will ...

  22. pSiM24: Simplifying Plant Genetic Engineering

    Type
    Blog Post
    Published
    Sept. 29, 2015, 2:30 p.m.
    ...modified with duplicated enhancer domains and characterized in studies of tobacco, Arabidopsis, and corn...paper at Addgene. Other relevant blog posts 3 Challenges in Plant Synthetic Biology Quick, Versatile Plant...

  23. Mapping the 4D nucleome with CRISPR/Cas9

    Type
    Blog Post
    Published
    Aug. 11, 2015, 2:30 p.m.
    ...inter- and intrachromosomal dynamics, and how they change in response to the cell cycle or other stimuli....intrachromosomal loci, a major benchmark in characterizing the 4D nucleome. Future modifications and applications...

  24. London Calling - Addgene’s New Europe Office in London

    Type
    Blog Post
    Published
    June 10, 2014, 3:20 p.m.
    ...States - Cambridge, MA to be exact. Today, that changes. Today, Addgene launches a brand new Europe office...scientists together from all over the world to exchange research materials in an easy way. She has a passion...

  25. CRISPR 101: Drug discovery and CRISPR

    Type
    Blog Post
    Published
    May 4, 2023, 1 p.m.
    ...model can be generated, and drugs screened for a change in pathology. If the disease pathology is complex...Target identification Not all diseases are fully characterized or have a simple pathology. In these cases, ...

  28. New Viral Vectors - Fall 2024

    Type
    Blog Post
    Published
    Oct. 3, 2024, 1:15 p.m.
    ...types of the basal ganglia. They work via newly-characterized enhancers that enable a whole host of (awesome...AAV-GfaABC1D-Cre-4x6T AAV5 Recombinases Stanley Thomas Carmichael New viral prep pAAV-EF1a-fDIO-Cre AAV5 Recombinases...

  30. SunTag and Fluorescent Imaging

    Type
    Blog Post
    Published
    March 28, 2017, 2:30 p.m.
    ...localized, and how its localization and expression may change across various conditions. However, this system...Improved brightness and signal-to-noise ratio Less chance of phototoxicity Reduced photobleaching Simplified...

  32. Plasmids 101: Positive and Negative Selection for Plasmid Cloning

    Type
    Blog Post
    Published
    Aug. 22, 2019, 12:43 p.m.
    ... interest by taking advantage of bacterial characteristics such as prototrophy, the ability to synthetize...used for negative selection on 5% sucrose plates. Exchange of the sacB gene for the gene of interest allows...

  33. Sleeping Beauty Awakens for Genome Engineering

    Type
    Blog Post
    Published
    June 30, 2015, 2 p.m.
    ...cells, but they are susceptible to cells’ defense mechanisms. The use of non-viral vectors, like transposons...sequences and then testing various combinations of changes. The basic functional version of the Sleeping Beauty...

  34. 10 Ways to Share Your Science!

    Type
    Blog Post
    Published
    May 13, 2014, 8:34 p.m.
    ...people like a good story and science involves characters – in this case you – on a quest to ask and answer...   Consider participating in a future SciFund Challenge. While the goal is ostensibly to get some funding...

  35. Advice for Choosing a Research Project

    Type
    Blog Post
    Published
    April 17, 2014, 2:45 p.m.
    ... apart a piece that can address a topic in a mechanistic way using the technology available.” Choosing...combining “new discoveries or technologies increase chances that your project will be fresh as well.” Don't...

  36. RUBY-Red Siliques

    Type
    Blog Post
    Published
    March 1, 2022, 2:15 p.m.
    ... positive plants, but screening these can be challenging and requires specialized equipment. Reporters...Department at the University of North Carolina at Chapel Hill. He has a passion for microscopy and beautiful...

  39. New Viral Vectors - Winter 2025

    Type
    Blog Post
    Published
    Jan. 28, 2025, noon
    ...Optogenetics Gordon Fishell New viral prep pAAV_BiCHATe27_dTomato_nlsdTomato AAV-PHPeB Control Gordon Fishell New... New viral prep pAAV_BiCHATe27_ChR2_mCherry AAV-PHPeB Optogenetics Gordon Fishell New viral prep pAAV_BiVIPe4...

  40. Viral Vectors 101: Transductions

    Type
    Blog Post
    Published
    April 30, 2024, 1:15 p.m.
    ...involve DNA incorporation into the cell, but the mechanisms vary. Why transduce? So why use a virus to deliver...transduction Transductions utilize the ‘normal’ mechanism of viral infiltration into a cell. The twist is...
Showing: 481 - 520 of 792 results