We narrowed to 529 results for: arl
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  TypeBlog PostPublishedOct. 11, 2017, 1:44 p.m....teacher professional development program that trains nearly 100 teachers each year, with workshops held at ...
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  Enabling Precision Functional Genomics with the Target Accelerator Plasmid CollectionTypeBlog PostPublishedMay 11, 2017, 2:30 p.m....PMC5120861. While there is much work to do, these early pilot studies have demonstrated technical feasibility...
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  Addgene’s Viral Service - Why Virus? Why Now?TypeBlog PostPublishedMarch 23, 2017, 2:30 p.m....fulfilling our mission for an even bigger impact. In early 2016 we surveyed hundreds of scientists about various...
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  Opto-Nanobodies: Using Light to Manipulate Cell Signaling and Protein PurificationTypeBlog PostPublishedNov. 19, 2019, 2:08 p.m....light-based control of signaling pathways. This is particularly exciting because using light to control signaling...
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  Choosing a CRISPR Nuclease: Site Accessibility, Specificity, and SensitivityTypeBlog PostPublishedNov. 5, 2019, 1:28 p.m....NG (Nishimasu et al., 2018). The David Liu Lab similarly described xCas9, which displayed the ability to...
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  Hot Plasmids December 2018 - C. elegans RNAi, TurboID, Detecting Viral Outbreaks, and Protein Binding Specificity ToolsTypeBlog PostPublishedDec. 6, 2018, 1:34 p.m....miniTurbo, which utilize non-toxic biotin, but label nearly as quickly as APEX2. What’s more, since the enzymes...
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  How Addgene Creates ContentTypeBlog PostPublishedNov. 17, 2022, 2:15 p.m....final check before publication. Do research! Nearly everything we write entails a primary literature...
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  Plasmids 101: Screens vs. SelectionsTypeBlog PostPublishedNov. 10, 2022, 2:15 p.m....both a screen and a selection, it is important to clearly define what type of factor you are looking for ...
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  AAV Q&A with Tim MilesTypeBlog PostPublishedMay 17, 2022, 1:15 p.m....Would you recommend any liver specific capsid, particularly one that can target the epithelial cells in ...
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  Hot Plasmids - February 2022TypeBlog PostPublishedFeb. 22, 2022, 2:15 p.m....create a genome-wide library capable of performing similarly to Cas9 screens in a compacted library. Overall...
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  Antibodies 101: Monoclonal AntibodiesTypeBlog PostPublishedJune 29, 2021, 1:15 p.m....for your experiment Monoclonal antibodies are particularly useful when you want to ensure that the antibody...
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  Viral Vectors 101: Types of virusesTypeBlog PostPublishedJune 6, 2023, 1:15 p.m....to specific cell types of interest. This is a particularly nice feature as organ-specific injections, or...
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  Viral Vectors 101: The AAV Retrograde SerotypeTypeBlog PostPublishedApril 27, 2023, 1:15 p.m....these vectors can exhibit spurious expression, particularly at the injection site (Fischer, KB. 2019). The...
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  7 Tips to Secure a STEAM Internship This SummerTypeBlog PostPublishedFeb. 2, 2021, 2:15 p.m....Addgene blog Check out other tools and resources for early career researchers Applying for jobs? Check out ...
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  Back to Bacteria: CRISPR gRNA Multiplexing Using tRNAsTypeBlog PostPublishedJune 2, 2015, 6:06 p.m....most abundant molecules in a cell, this system is clearly also robust enough to ensure high levels of gRNA...
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  CRISPR 101: Non-Homologous End JoiningTypeBlog PostPublishedApril 16, 2015, 3:45 p.m....deletions) if NHEJ joins the distal ends together. Similarly, it may be possible to direct insertion of an ...
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  Pooled CRISPR Libraries Offer Genome-Wide Control for Large-Scale Functional ScreensTypeBlog PostPublishedFeb. 24, 2015, 7:50 p.m....test was the perfect complement for one conducted earlier by the Zhang lab for GeCKO, a lentiviral CRISPR...
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  3 Challenges in Plant Synthetic BiologyTypeBlog PostPublishedJuly 22, 2014, 5:46 p.m....challenge associated with molecular plant parts, particularly for applied projects intended for commercialization...
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  Plasmids 101: Yeast VectorsTypeBlog PostPublishedFeb. 25, 2014, 7:11 p.m....plasmid copy number within the bacterial cell. Similarly, the specific ORI elements included within a yeast...
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  Kiran Musunuru on the Newest TALEN Genome-Editing SystemTypeBlog PostPublishedDec. 10, 2013, 3:13 p.m....knock-out mice, but for various reasons it is not nearly as efficient in human stem cells. What genome editing...