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  1. Viral Vectors 101: The Retroviral Lifecycle

    Type
    Blog Post
    Published
    July 27, 2023, 1:15 p.m.
    ...Microbiological Reviews, 56(3), 375–394. https://doi.org/10.1128/MR.56.3.375-394.1992. PubMed PMID: 1406488. PubMed...of Virology, 14(5), 1132–1141. https://doi.org/10.1128/JVI.14.5.1132-1141.1974. PubMed PMID: 4372391. ...Journal of Virology, 82(5), 2376. https://doi.org/10.1128/JVI.02100-07. PubMed PMID: 18094172. PubMed Central...

  2. A Guide to Getting Started in Undergrad Research

    Type
    Blog Post
    Published
    June 8, 2021, 1:15 p.m.
    ...diversity. Science 367:749.2-750 . https://doi.org/10.1126/science.aba8039 Cordova FA (2016) Embrace uncertainty...uncertainty. Science 351:994–994 . https://doi.org/10.1126/science.351.6276.994 Moore E (2021) One mentor ...a network of mentors. Science. https://doi.org/10.1126/science.caredit.abi6939 Additional resources on...

  3. CRISPR 101: Cytosine and Adenine Base Editors

    Type
    Blog Post
    Published
    Feb. 13, 2025, 2:15 p.m.
    ...Science Advances, 3(8), eaao4774. https://doi.org/10.1126/sciadv.aao4774 Lam, D. K., Feliciano, P. R., Arif...York, N.Y.), 353(6305), aaf8729. https://doi.org/10.1126/science.aaf8729 Rees, H. A., Komor, A. C., Yeh,...York, N.Y.), 368(6488), 290–296. https://doi.org/10.1126/science.aba8853 Zhang, X., Zhu, B., Chen, L., Xie...

  4. Mapping the 4D nucleome with CRISPR/Cas9

    Type
    Blog Post
    Published
    Aug. 11, 2015, 2:30 p.m.
    ...Natl Acad Sci U S A. 2015 Mar 10;112(10):3002-7. doi: 10.1073/pnas.1420024112. Epub 2015 Feb 23. Pubmed. ...

  5. New and Upcoming Viral Vectors - December 2019

    Type
    Blog Post
    Published
    Dec. 19, 2019, 2:40 p.m.
    ...pAAV-Ef1a-fDIO mCherry 99130 AAVrg pAAV-mDlx-NLS-mRuby2 112677 AAV1, AAV2 pOTTC1032 - pAAV EF1a Nuc-flox(mCherry...pAAV-Ef1a-DIO EYFP 114471 AAV5 pAAV-Ef1a-fDIO mCherry 112677 AAV2 pOTTC1032 - pAAV EF1a Nuc-flox(mCherry)-EGFP...

  8. Progress Towards a PAM-Free CRISPR

    Type
    Blog Post
    Published
    March 7, 2024, 2:39 p.m.
    ...-Cas9 variants. Science 368,290-296(2020). DOI:10.1126/science.aba8853 (Plasmids available here)   Nishimasu...targeting space. Science 361,1259-1262(2018). DOI:10.1126/science.aas9129   Zhang W, Yin J, Zhang-Ding Z,...

  9. Of Myc and Men

    Type
    Blog Post
    Published
    Jan. 19, 2023, 2:15 p.m.
    ...product. Mol Cell Biol 5:3610–3616. https://doi.org/10.1128/mcb.5.12.3610-3616.1985 Munro S, Pelham HR (1984...sequence context. Sci Signal 13. https://doi.org/10.1126/scisignal.aax9730  Additional resources on the ...

  10. INTEGRATE: Bacterial Genome Engineering Using CRISPR-Transposons

    Type
    Blog Post
    Published
    Dec. 7, 2020, 2:53 p.m.
    ...transposases. Science 365:48–53 . https://doi.org/10.1126/science.aax9181 Strecker J, Ladha A, Makarova KS...transposases.” Science 368:eabb2920 . https://doi.org/10.1126/science.abb2920 Vo PLH, Ronda C, Klompe SE, Chen...

  11. Overcoming the AAV Size Limitation for CRISPR Delivery

    Type
    Blog Post
    Published
    Sept. 16, 2020, 1 p.m.
    ... Systems. Science 339:819–823 .https://doi.org/10.1126/science.1231143  Cox DBT, Gootenberg JS, Abudayyeh...CRISPR-Cas13. Science 358:1019–1027 . https://doi.org/10.1126/science.aaq0180  Fine EJ, Appleton CM, White DE...

  12. The PAM Requirement and Expanding CRISPR Beyond SpCas9

    Type
    Blog Post
    Published
    Aug. 20, 2020, 2:30 p.m.
    ...CRISPR-Cas13. Science 358:1019–1027 . https://doi.org/10.1126/science.aaq0180 Find plasmids from this paper ...variants. Science 368:290–296 . https://doi.org/10.1126/science.aba8853 Zetsche B, Gootenberg JS, Abudayyeh...

  13. Rett Syndrome: A History of Research and Therapeutic Outlooks

    Type
    Blog Post
    Published
    Nov. 19, 2020, 2:15 p.m.
    ...Syndrome. Science 315:1143–1147 . https://doi.org/10.1126/science.1138389 Le TTH, Tran NT, Dao TML, Nguyen...Requires MeCP2. Science 333:186–186 . https://doi.org/10.1126/science.1206593 Powers S, Miranda C, Dennys-Rivers...

  14. Viral Vectors 101: Systemic Capsids

    Type
    Blog Post
    Published
    Oct. 12, 2023, 1:15 p.m.
    ...barrier. PLoS Biology, 21(7), e3002112. https://doi.org/10.1371/journal.pbio.3002112 Jang, M. J., Coughlin, ...Science Advances, 9(16), eadg6618. https://doi.org/10.1126/sciadv.adg6618 Stanton, A. C., Lagerborg, K. A....

  15. Viral Vectors 101: AAV Variables That Matter

    Type
    Blog Post
    Published
    June 1, 2023, 1:15 p.m.
    ...Receptor. Journal of Virology, 92(7). https://doi.org/10.1128/jvi.02213-17 Favre, D., Blouin, V., Provost, N....Virology, 76(22), 11605–11611. https://doi.org/10.1128/JVI.76.22.11605-11611.2002 Griffin, J. M., Fackelmeier...

  16. A History of Genome Engineering in Popular Culture

    Type
    Blog Post
    Published
    Feb. 25, 2020, 2:15 p.m.
    ...CRISPR-Cas9. Science 346:1258096 . https://doi.org/10.1126/science.1258096 Gaudelli NM, Komor AC, Rees HA,... TALENs. Science 333:307–307 . https://doi.org/10.1126/science.1207773 ...

  17. RNA Interference in Plant Biology: New Tools for an Old Favorite

    Type
    Blog Post
    Published
    Oct. 27, 2020, 1:15 p.m.
    ...Cell 25:1507–1522 . https://doi.org/10.1105/tpc.113.112235 Morgens DW, Deans RM, Li A, Bassik MC (2016) ...Cell 24:1478–1493 . https://doi.org/10.1105/tpc.112.098509 Smits AH, Ziebell F, Joberty G, Zinn N, Mueller...

  20. Antibodies 101: Fc Effector Functions

    Type
    Blog Post
    Published
    May 18, 2023, 1:15 p.m.
    ...cancer immunotherapy.Sci. Adv.8,eabl9171(2022).DOI:10.1126/sciadv.abl9171 More resources on the Addgene blog...
Showing: 21 - 40 of 96 results