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Showing: 21 - 40 of 62 results

  1. The Breast Cancer Microenvironment: A Tumor’s Backstage Team

    Type
    Blog Post
    Published
    Jan. 31, 2019, 1:32 p.m.
    ... expression of TAK 1, an enzyme that controls apoptosis and regulates transcription. Without TKA1, cells...cells proliferate and cannot undergo apoptosis, thus multiplying uncontrollably and building up tumors....

  2. Viral Vectors 101: Chemogenetics

    Type
    Blog Post
    Published
    July 11, 2023, 1:15 p.m.
    ...Varenicline has been further modified to create ultrapotent PSEMS (uPSEMs) that have drastically increased... A, Basu J, Michaelides M, Sternson S (2019) Ultrapotent chemogenetics for research and potential clinical...

  3. Experimenting with New Careers while in Grad School

    Type
    Blog Post
    Published
    Feb. 25, 2016, 3:30 p.m.
    ... myidp.sciencecareers.org mentioned museums. Indianapolis is home to one of "The world’s biggest and best...children’s museum", The Children's Museum of Indianapolis. I drove passed these dinosaurs every day. They...

  4. Fluorescent Proteins 101: Photoactivatable Fluorescent Proteins

    Type
    Blog Post
    Published
    April 25, 2017, 2:30 p.m.
    ...fusion dynamics of mitochondria in healthy and apoptotic cells (9). PA-FPs have helped to revolutionize...is blocked during the Bax activation phase of apoptosis." J Cell Biol 164.4 (2004): 493-499. PubMed PMID...

  6. 8 Great Depositor Research Stories

    Type
    Blog Post
    Published
    Dec. 15, 2022, 2:15 p.m.
    ...directed DNA Demethylation: Guest blogger Daniel M. Sapozhnikov tells us how to use dCas9 (with no modifications...

  7. What's New in CRISPR - December 2019

    Type
    Blog Post
    Published
    Dec. 17, 2019, 2:37 p.m.
    ...rate of off-target genome edits compared to rat APOBEC1. Now, they’ve engineered SECURE adenine base editor...

  9. Antibodies 101: Epitope Tags

    Type
    Blog Post
    Published
    May 11, 2023, 1:15 p.m.
    ... as well. This tag is not suitable for use in apoptotic cells as Caspase3/7 both cleave after the DVPD...

  10. The Strength of Story Telling

    Type
    Blog Post
    Published
    Dec. 19, 2017, 2 p.m.
    ...it for a while and he eventually calmed down, apologised and admitted he’d been under a lot of pressure...

  13. Hot Plasmids - January 2023

    Type
    Blog Post
    Published
    Jan. 31, 2023, 2:15 p.m.
    ...  After using mCherry for FACS sorting of the weaponized T-cells (CAR-T cells) - and then delivering them...

  15. AAV Q&A with Tim Miles

    Type
    Blog Post
    Published
    May 17, 2022, 1:15 p.m.
    ...Miles, David Goertson, Xinhong Chen, and Miggy Chuapoco, and to all our participants for their time and...

  16. Viral Vectors 101: Viral Vector Elements

    Type
    Blog Post
    Published
    July 25, 2023, 1 p.m.
    ...ones listed previously). E3/E1B suppresses both apoptosis and the host immune response to the virus to allow...

  17. RaPID Detection of RNA-protein Interactions

    Type
    Blog Post
    Published
    Aug. 16, 2018, 12:40 p.m.
    ...Contamination Repository for Affinity Purification (CRAPome), to identify highly biotinylated background proteins...

  19. Viral Vectors 101: Calcium Sensors

    Type
    Blog Post
    Published
    Aug. 10, 2023, 1 p.m.
    ...GCaMP-X is a nucleus-targeted GCaMP6 with an extra apoCaM-binding motif to prevent aberrant binding of the...
Showing: 21 - 40 of 62 results