We narrowed to 44 results for: TRIM
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TypeBlog PostPublishedJune 21, 2018, 2:06 p.m....of endogenous proteins (notably, BRD2/3/4, CDK9, TRIM24, FLT3, BTK, and ALK) by linking small molecules...
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Uncertainty about Labor Law Brings More Uncertainty to Postdoc Wages
TypeBlog PostPublishedJan. 11, 2017, 3:30 p.m....salary raises at institutions will likely have a detrimental effect on the morale of postdocs, and indeed ... -
To Each HIS Own
TypeBlog PostPublishedMarch 2, 2023, 2:15 p.m....antibody, like this one developed by Dr. James Trimmer’s lab, to perform assays that they otherwise would... -
Tagging Optogenetics and Chemogenetics Receptors: Fluorescent Proteins and Other Options
TypeBlog PostPublishedMay 11, 2021, 1:15 p.m....fluorescent proteins can be, in some circumstances, detrimental to the expression of the protein of interest.... -
Hot Plasmids May 2018 - Optogenetics, Decaffeination, Biosensors, and Fluorescent Protein Tools
TypeBlog PostPublishedMay 15, 2018, 12:43 p.m....enables the degradation of caffeine (1,3,7-trimethylxanthine) and its conversion into xanthine. The majority... -
Antibodies 101: Choosing the Right Isotype
TypeBlog PostPublishedApril 6, 2023, 3 p.m....(08)60255-1 Manning, C. F., Bundros, A. M., & Trimmer, J. S. (2012). Benefits and Pitfalls of Secondary... -
Hot Plasmids: Winter 2025
TypeBlog PostPublishedMarch 11, 2025, 1:15 p.m....GTP-bound) Gα. Gα-YFP assembles into functional heterotrimers with endogenous Gβγ, enabling detection of activation... -
Introducing Addgene's New Search - Find Plasmids More Easily For Your Research!
TypeBlog PostPublishedDec. 3, 2019, 11:38 a.m....recombinant monoclonal antibody plasmids from the James Trimmer Lab published in eLife. Addgene is currently distributing... -
CRISPR-mediated Plant Base Editors
TypeBlog PostPublishedJan. 3, 2019, 1:35 p.m....strand, dramatically reducing the likelihood of detrimental indel formation. After binding with DNA, the ... -
Rett Syndrome: A History of Research and Therapeutic Outlooks
TypeBlog PostPublishedNov. 19, 2020, 2:15 p.m....in which too much of the MECP2 protein is as detrimental as too little, resulting in MECP2 duplication... -
To Codon Optimize or Not: That is the Question
TypeBlog PostPublishedNov. 12, 2020, 2:15 p.m....changes to a gene sequence can cause unexpected detrimental results to the protein. Codon optimization could... -
Hot Plasmids - November 2023
TypeBlog PostPublishedNov. 14, 2023, 3:35 a.m....thick-section and whole-mount labeling techniques. The Trimmer lab’s anti-PSD-95 [K28/43R] recently passed their... -
Viral Vectors 101: Pseudotyping
TypeBlog PostPublishedApril 20, 2021, 2:30 p.m....vesicular stomatitis virus G protein. VSV-G is a trimeric protein that binds phosphatidylserine and low-... -
March for Science
TypeBlog PostPublishedApril 21, 2017, 2:30 p.m....supporting many different positions. It would be detrimental for them to be homogenized or thought of as just... -
Antibodies 101: Single Chain Fragment Variables (scFvs)
TypeBlog PostPublishedJune 3, 2021, 1:15 p.m.... antibodies for neuroscience research from the Trimmer lab Check out Addgene's latest project to develop... -
Using Phosphoserine to Study Protein Phosphorylation
TypeBlog PostPublishedJune 23, 2016, 2:30 p.m....-through translation of many stop codons and detrimental effects on cell growth. The C321.ΔA strain was... -
Plasmids 101: Dimers and Multimers
TypeBlog PostPublishedJan. 10, 2023, 2:15 p.m....various multimeric forms (e.g. concatemers, dimers, trimers, tetramers). Since then, multimerization has been... -
Plasmids 101: Repressible Promoters
TypeBlog PostPublishedDec. 20, 2022, 2:15 p.m....Park, S., Hill, C. et al. A LexAop > UAS > QUAS trimeric plasmid to generate inducible and interconvertible... -
Transferable Skills Guide: Teamwork
TypeBlog PostPublishedNov. 28, 2017, 2 p.m....excess people who are not contributing will detrimentally affect a team’s morale and efficiency. You could... -
Antibodies 101: Validation
TypeBlog PostPublishedMarch 24, 2022, 1:15 p.m..../19420862.2015.1100787 Taussig MJ, Fonseca C, Trimmer JS (2018) Antibody validation: A view from the ...