Viral Vectors 101: Integrase-Deficient Lentiviral Vectors
Type
Blog Post
Published
May 13, 2025, 1:15 p.m.
...over three decades. Widely used across various research applications, they have become indispensable tools...and organisms. They can be used for a variety of research purposes, like creating stable cell lines, delivering...vectors work with regards to integration, and how researchers have modified them to prevent this integration... DNA… forever!
This can be an advantage for researchers looking to generate long-lasting changes in cells...genome (Figure 1). IDLVs were first discovered by researchers investigating HIV integrase mutants in the early... choice for certain types of clinical or basic research applications.
Considerations for IDLV use
If you...you know how IDLVs could be useful in your own research, we wish you the best of luck with any experiments...