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We narrowed to 809 results for: TES

Showing: 381 - 400 of 809 results

  1. Countdown to Halloween @Addgene

    Type
    Blog Post
    Published
    Oct. 29, 2014, 5:26 p.m.
    ...through 2009, though I suspect that our costume contests were indeed occurring earlier but that the photo...protect the innocent revelers. Our Halloween costume contests have become an annual tradition in which we choose...finding out who wins this year’s Addgene costume contest, like us on Facebook and checkout our FB page on...

  2. AAV Packaged on Request is Here!

    Type
    Blog Post
    Published
    Jan. 10, 2025, 1:01 p.m.
    ...our in-stock service: ddPCR, purity testing, and sterility testing, plus viral genomic sequencing to confirm...AAVrg and 7 × 1012 GC/mL for AAV2. There are no quotes or special processes involved; simply request your...

  3. New Viral Vectors - March 2024

    Type
    Blog Post
    Published
    March 5, 2024, 2:15 p.m.
    ...only March!)  In our repository, you'll find the latest iteration of GCaMP, GCaMP8, available in new serotypes...repository  Name Serotype Category Depositor  Notes AAV-CAG-jGCaMP8s-WPRE AAV1 Biosensor Looger New...forgot to use the link below to keep up with the latest in Addgene's viral vectors services and resources...

  4. The CRISPR Software Matchmaker: A New Tool for Choosing the Best CRISPR Software for Your Needs

    Type
    Blog Post
    Published
    Nov. 3, 2015, 3:30 p.m.
    ...you need access to raw data, the target sites, off-target sites, scores and the statistics that go into...genome contains only 0.66 million targetable NGG PAM sites whereas the human genome has about 300 million. ...newer tools may still prove somewhat useful for the latest NTT targeting Cas protein, Cpf1. Separately, on-target...

  5. Addgene Stands with the Scientific Community

    Type
    Blog Post
    Published
    April 23, 2025, 1:30 p.m.
    ...in the United States but around the world. As an organization that directly collaborates with NIH-funded... are constrained. This collaborative approach eliminates redundant work, saving time and allowing precious...

  7. Optogenetics + CRISPR, Using Light to Control Genome Editing

    Type
    Blog Post
    Published
    Sept. 3, 2020, 12:15 p.m.
    ...to activate gene transcription. The researchers tested a variety of combinations to optimize both fusion...500nm). By fusing the two pdDronpa domains to the sites flanking the DNA-binding cleft of Cas9, the fluorescent...Upon light activation, dCas9 is released within minutes and red foci formed 20-40 min later. The CASANOVA...synthetase, read this article). The group first tested photocaging various lysines in Cas9 to determine...

  8. Reflections and Looking Ahead

    Type
    Blog Post
    Published
    Feb. 25, 2025, 2:15 p.m.
    ...enriched our repository with 15,020 new plasmids — a testament to the scientific community's commitment to open...brings us closer to making an impact on humanity's greatest challenges. Thank you for being part of this incredible...future of science. Want to learn more about our latest developments? Subscribe to the Addgene newsletter...

  9. Bringing Sustainable Practices to the Lab: Innovations

    Type
    Blog Post
    Published
    March 7, 2019, 2:39 p.m.
    ...environmental impact of those processes? Who even regulates them? You may be surprised to learn that it hasn... been 50 years since the creation of the United States Environmental Protection Agency, which started ...scientists washed and reused materials such as glass pipettes or inoculation loops. While single-use is now ...

  10. Top 10 Open Science Developments of 2013

    Type
    Blog Post
    Published
    Dec. 19, 2013, 3:46 p.m.
    ...So, as 2013 comes to a close, let’s take a few minutes to reflect on some of the most noteworthy developments...database to gather the results of Myriad's genetic tests for breast and ovarian cancer risk directly from...granted via a public repository or authors’ own web sites. 9)      The year 2013 has also been the year of...

  11. From our Table to Yours: An Inside Look at Lunch at Addgene

    Type
    Blog Post
    Published
    Nov. 27, 2013, 2:54 p.m.
    ... was pumpkin. Everyone gets to vote for their favorites, and trophies are awarded and coveted. I’ve only...we head into Thanksgiving weekend in the United States, I look forward to gathering around a large table...you have any traditions that you share with your labmates, be they food related or not? We would love to...

  12. X-CHIME: Context Dependent Germline Knockout in Immune Cells

    Type
    Blog Post
    Published
    Jan. 16, 2024, 6:13 p.m.
    ..., M.W., Nguyen, T.H., Coxe, M.A., Miller, B.C., Yates, K.B., Gillis, J.E., Sen, D.R., Gaudiano, E.F., ..., Haining, W.N., & Sharpe, A.H. (2019). PTPN2 regulates the generation of exhausted CD8+ T cell subpopulations...0480-4 LaFleur, M. W., Nguyen, T. H., Coxe, M. A., Yates, K. B., Trombley, J. D., Weiss, S. A., Brown, F....

  13. 2023 and 2024: Reflections and Looking Ahead

    Type
    Blog Post
    Published
    Jan. 23, 2024, 2:15 p.m.
    ...to make it more accessible. Other accessibility updates include a printer-friendly design and alt text ...on all images. We have also made accessibility updates to our website, which receives 3.8 million visitors...perspective on Addgene through her LinkedIn page. She invites you to connect with her there. More on the Addgene...

  14. What's New in CRISPR - September 2019

    Type
    Blog Post
    Published
    Sept. 10, 2019, 12:56 p.m.
    ...transcriptional regulators. In this system, Cas9 generates a double-stranded DNA break at the genomic loci... the universal sgRNA is not predicted to target sites in the human, pig, or zebrafish genome, this system... Using the structure of CasX at eight different states of assembly from cryo-electron microscopy, the ...

  15. Same Addgene, New Look - Why We Redesigned Our Homepage & Mascot

    Type
    Blog Post
    Published
    Dec. 5, 2019, 1:49 p.m.
    ...months of strategizing, designing, developing, testing - and repeat - we’re proud and excited to finally...homepage While users are increasingly accessing websites other than through the ‘front door,’ the homepage...Additionally we also wanted to highlight our blog, daily updates, and offer better exploration throughout the site...

  16. Who Gives a Tweet? 9 Facts About Scientists on Twitter

    Type
    Blog Post
    Published
    June 26, 2017, 1:31 p.m.
    ...for scientific titles generated from the United States Standard Occupational Classification System  and...female to male scientific authorship in the United States (0.428). 4. The #1 (re)tweeted domain by scientists...scientists was Instagram Social media and news sites were also popular. Perhaps scientists, like nonscientists...

  17. CUT&RUN: An Improved Method for Studying Protein-DNA Interactions

    Type
    Blog Post
    Published
    Feb. 13, 2018, 2:51 p.m.
    ... may appear to be binding at particular genomic sites when in fact they are just non-specific or indirectly... MNase. Once MNase has been localized to target sites, the nuclease is briefly activated to digest the... an excellent additional measure of DNA binding sites in combination with existing ChIP-seq data sets,...

  18. CASTing Off for New Shores in Human Genome Editing

    Type
    Blog Post
    Published
    June 10, 2025, 1:15 p.m.
    ...sequences into genomic DNA downstream of gRNA-specified sites. Created with BioRender.com. CASTs quickly became...mutations require individualized optimizations, safety testing, and approval. In contrast, a system that can deliver... the National Academy of Sciences of the United States of America, 114(35), E7358–E7366. https://doi.org...

  19. An Addgene Co-op: The Intersection of Fun, Friendship, and Work

    Type
    Blog Post
    Published
    June 29, 2023, 7 p.m.
    ...production on a protocol video. Don't worry - no pipettes were harmed in the making of this photo!  Here... The sense of trust and comfort I had with my teammates acted as my safety net and trampoline all at once... I really believe that the culture at Addgene cultivates trust between coworkers and that trust then translated...

  20. Antibodies 101: Fc Effector Functions

    Type
    Blog Post
    Published
    May 18, 2023, 1:15 p.m.
    ...immune response against a pathogen. The Fc domain creates a link between the antibody and other parts of ...opsonization of IgG and IgM antibodies on a pathogen activates the immune system's classical complement pathway.... (2008). The immunoglobulin constant region contributes to affinity and specificity. Trends in Immunology...
Showing: 381 - 400 of 809 results