We narrowed to 823 results for: lars

...problem can be attributed to communication, and in particular communication about experimental methods and ... and funding, so institutions and funders, to a large extent, hold the keys to getting transparency and...journals including Trends in Cell Biology, Cell, Molecular Cell, Developmental Cell, and Cell Stem Cell.  ...

...insects, mammals, and plants, among others. I particularly enjoyed the emphasis that microbes are neither... "The Mistborn series is the first 3 books of a larger epic of fantasy novels. Set in a world where 1000...Control Jonathan Strange & Mr. Norrell by Susanna Clarke "A quasi-historical/fantasy fiction. Two dueling...

...instrumental in interpreting human variation at large scales and making personalized medicine a reality...the a bacterial periplasmic binding protein, one similar to the protein which gave rise to the iGluSnFR ...artificial leaf replica means creating a “leaf” with similar permeability of water and nutrients and colonization...

... Senior Researcher who investigates the molecular and cellular etiopathomechanisms of ischemic stroke,...brain injury Dr. Gohar Tsakanova, Institute of Molecular Biology of the NationalAcademy of Sciences of ...

...being used to study SARS-CoV-2. The resurgence in popularity of the hACE2 transgenic mouse strain, for example...murine ACE2 (Subbarao et al., 2006). Now that a similar phenomena is appearing with regards to SARS-CoV...SARS-CoV-2, this mouse strain is regaining popularity. The Jackson Laboratory, a nonprofit research institution...

...the book. The best tip in the book is to have a regular writing schedule, even if you only write for a ...generic, so they need to be edited to suit your particular field of research.   Citations tools DOI Citation... time. Mendeley Mendeley works much like other popular citation managers, but Mendeley is free to use....

...affected the stem cell community – a community largely created due to Yamanaka’s seminal work. It didn't... prominent role in the scientific endeavor – particularly in fields like stem cell biology where questions...about his clinical trial patients with advanced macular degeneration; Laurenz Studer discussed his work...

... the heart of delegating for success.  Meet regularly before during and after the assignment to discuss...review project progress. I recommend putting a regular check-in meeting on the calendar even if it is ... Resources on the Addgene Website Are You a Molecular Biologist? Find Plasmids for Your Research Here...

... data, then the chance is that you have handled large data sets and are familiar with statistical analysis...of that, perhaps you were involved in some extracurricular activities – did you volunteer to do science..., many universities make their job postings and salary expectations public, so start by looking at these...

...strong collaborative research team motivated by similar visions and goals? We continue our conversation... time in his office, he gradually incorporated regular group meetings, journal clubs, and focused sub-...and a friend. George Church runs his lab fairly similarly to his advisor Wally Gilbert: “Very interdisciplinary...

...engagement and access to growth opportunities, not salary and benefits. Therefore, lab selection should focus...Alternatively, perhaps the lab publishes and presents regularly with labs around the world. You may prefer a more... making this choice.  How big is the lab? While larger labs tend to be more "chaotic" and offer less micromanaging...

...can either express the plasmid DNA transiently (similar to bacteria) or incorporate the genetic material...virus (EBV) nuclear antigen 1 (EBNA1) or the SV40 large-T antigen (293E or 293T cells), allow for episomal.... Positive selection in mammalian cells works similarly to that in bacteria and a table of the most commonly...

... almost all of the attendees were going to be molecular biologists. This was not at all the case. The ...neurobiology (and really in all of biology) require large data sets. Whether these data sets include videos... make the virus for you. Neuroscientists are particularly interested in using AAVs because they provide...

...used to investigate the effects of activating particular signaling pathways in specific cell types (typically...typically neurons). While all of these viruses are popular, pAAV-hSyn-DIO-hM4D(Gi)-mCherry contains a double...animals, where cre expression is restricted to a particular cell type. The human synapsin promoter further...

...NG (Nishimasu et al., 2018). The David Liu Lab similarly described xCas9, which displayed the ability to... (HypaCas9). This nuclease showed decreased or similar off-target activity, relative to eSpCas9 and SpCas9...degree of both specificity and sensitivity across a large number of loci and gRNA lengths. Recent alternatives...

...could code the best operations software possible. Similarly, when the developers needed to know information...relationship-building and influence. You’ll need a large deal of influence and strong relationship-building...Technologies for the North America region. She is particularly interested in DNA sequencing tech, and the intersection...

...noninvasive methods for manipulating cell activity, particularly in the brain, and holds promise in the development...development of future therapies. Our popular plasmid encoding a Cre dependent version of the DREADD hM3D ...on availability date or to be notified when a particular catalog item is available for order please email...

...cell type? You can use DNA sequencing or other molecular cloning techniques to determine CRISPR/sgRNA efficiency...site in the genome you are trying to target play a large role in Cas9 activity and efficiency (Sander and... structure and genomic recognition sites play a large role in CRISPR-Cas9 efficiency. They continued to...

...genes, tags, truncations, and codon optimizations similar to those found in the bacterial expression plasmids...Fukushi S, Watanabe R, Taguchi F (2008) Pseudotyped Vesicular Stomatitis Virus for Analysis of Virus Entry Mediated...SARS Coronavirus Spike Proteins. In: Methods in Molecular Biology. Humana Press, pp 331–338 https://doi....

...offset due to the nanobody-GFP interaction). The modularity of the system provides researchers better flexibility...comparable to commonly used CRISPR/Cas9 methods for large inserts. However, this system has a much lower error... a fluorescent protein coupled to a specific subcellular localization peptide. By combining three different...