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We narrowed to 799 results for: mpl

Showing: 581 - 600 of 799 results
  1. What's New in CRISPR - March 2020

    Type
    Blog Post
    Published
    March 10, 2020, 1:15 p.m.
    ... Blue light renders the NLS accessible and the complex enters the nucleus where dCas9-Mxi1 can repress.... In the dark, the NLS is inaccessible and the complex remains in the cytoplasm. Read the paper in Cellular...
  2. Mapping the 4D nucleome with CRISPR/Cas9

    Type
    Blog Post
    Published
    Aug. 11, 2015, 2:30 p.m.
    ...could also have major applications to cancer, for example, the visualization of chromosomal translocations...Addgene. A protein-tagging system for signal amplification in gene expression and fluorescence imaging....
  3. In Living Color: The Skinny on In Vivo Imaging Tools

    Type
    Blog Post
    Published
    March 27, 2014, 5:14 p.m.
    ...signal-to-background ratio, thus, allowing higher resolution in samples containing substantial autofluorescence background...direction of biosensors capable of revealing, for example, how muscles work inside a living animal. For those...
  4. Addgene's a Nonprofit? Nonprofit Awareness Day 2017

    Type
    Blog Post
    Published
    June 5, 2017, 3:19 p.m.
    ...information.” Addgene is here to help scientists accomplish their goals. Many nonprofits must spend a lot...thought leader in scientific sharing, leading by example to increase sharing in the community Addgene fosters...
  5. Are Hybrid Guide RNAs Right for Your CRISPR Application?

    Type
    Blog Post
    Published
    Jan. 27, 2026, 2:14 p.m.
    ...sequence reduces the stability of the genome-bound complex. This decreases the Cas protein’s tolerance for...on-target efficacy. For perfect sequence matches, the complex is stable enough that the DNA substitution doesn...
  6. CASTing Off for New Shores in Human Genome Editing

    Type
    Blog Post
    Published
    June 10, 2025, 1:15 p.m.
    ...2017). Type I CAST systems rely on the Cascade complex minus its nuclease component, Cas3, while Type ... systems; Cascade shown) combines with a donor template and transposon proteins (Tns) to integrate large...
  7. Bringing Sustainable Practices to the Lab: Recycling

    Type
    Blog Post
    Published
    Feb. 14, 2019, 2:35 p.m.
    ...prepaid return shipping label. To return the box, simply peel your address sticker off the box, remove the...packaging (no coated tissue culture plates, for example). Check the link for more details on what they ...
  8. Embracing Serendipity: A Crucial Element in the PhD Journey

    Type
    Blog Post
    Published
    April 25, 2024, 1:15 p.m.
    ...serendipity during your PhD studies and offer two simple steps to welcome these unforeseen moments. Widening...everything is a miracle.” This quote encourages us to contemplate our approach to life and how our viewpoints influence...
  9. Cellosaurus: A Cell Line Information Database

    Type
    Blog Post
    Published
    Feb. 21, 2023, 2:15 p.m.
    ...hybridoma, etc.), as well as sex and age at time of sampling if available. STR profiling for human, mouse, ... publications cited. If the information seems incomplete or unclear, Bairoch follow up via email to the...
  10. Bricking Science: Portraying Scientific Reality Through LEGO

    Type
    Blog Post
    Published
    Nov. 29, 2016, 3:30 p.m.
    ...wrong. Whether it be a bad fridge freezing your samples, or a dysregulated water bath boiling your experiments...faced an odd situation with experiments? Our art simply mirrors our lives at this point! It was a great...
  11. Tips for Improving Your Next Manuscript

    Type
    Blog Post
    Published
    Nov. 22, 2016, 3:30 p.m.
    ...spent collecting it will have been worthless. But simply writing down your data doesn’t guarantee a publication...portion of the paper will be generated. After you complete a publication quality figure, produce the figure...
  12. Management for Scientists: Managing vs. Leading

    Type
    Blog Post
    Published
    March 31, 2015, 4:08 p.m.
    ...or leading. All three roles are important to accomplishing any goal or finishing any project. Doers are...be successful in a specific role or cycle. For example, if you try to lead when you are expected to be...
  13. Advice for Choosing a Research Project

    Type
    Blog Post
    Published
    April 17, 2014, 2:45 p.m.
    ...typical research project can take several years to complete and has multiple benchmarks. Think about what ...Researchers should  pick a topic that “looks at the complexity of biology and break apart a piece that can address...
  14. Plasmids 101: Antibiotic Resistance Genes

    Type
    Blog Post
    Published
    Jan. 30, 2014, 3:29 p.m.
    ...gene of interest is cloned into/inactivates or completely removes (in the case of Gateway cloning) one ...Posts Learn How to Use Blue White Screening to Simplify Your Cloning Experiments See Where You Can Find...
Showing: 581 - 600 of 799 results