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We narrowed to 898 results for: CAN

Showing: 741 - 760 of 898 results
  1. Hot Plasmids: Winter 2025

    Type
    Blog Post
    Published
    March 11, 2025, 1:15 p.m.
    ...with a flexible linker where a protein of interest can be inserted. B) Protein expression and labeling procedure...voltage indicator (GEVI) than previous versions. ASAP5 can be imaged using one- or two-photon microscopy to ...Altogether, if you want a negative-going GEVI that can be used in different illumination regimes with fast...with non-neurodegenerative diseases (Diabetes & cancer). Image adapted from Wu and Wang 2024 under a CC-BY...
  2. Magnetic Control of Proteins: More than a Dream

    Type
    Blog Post
    Published
    Sept. 24, 2024, 1:15 p.m.
    ...ve ever had an MRI, you know that magnetic fields can pass right through our tissues unimpeded. Andrew ...engineering approaches and that magnetosensitive tools can be developed from other fluorescent proteins.  Currently...optogenetic tools, they’re optimistic that MagLOV can be similarly adaptable into future magnetogenetic...Maria’s screens of AsLOV2 variants showed some significant gains! After a few more rounds of mutagenesis...ideas and are happy to speculate, they know they can’t answer these questions alone. They readily admit...Confined Persistent Diradical Emitter. Journal of the American Chemical Society, 145(25), 13615–13622. https:...
  3. Course-Based Undergraduate Research Experiences (CUREs)

    Type
    Blog Post
    Published
    Feb. 9, 2023, 2:15 p.m.
    ...confidence and learn to work independently, which can lead to greater success in meeting educational goals...without challenges. Real research is messy, and it can be difficult to give up the control embedded in “... Course-based undergraduate research experiences can make scientific research more inclusive. CBE Life...the training of the mind to think something that cannot be learned from textbooks” (Brian, 1996). But is...citrate synthase and presented their findings at the American Society for Biochemistry and Molecular Biology...
  4. Experimenting with New Careers while in Grad School

    Type
    Blog Post
    Published
    Feb. 25, 2016, 3:30 p.m.
    ...science outreach, not only can I easily share science with the public, but I can watch and learn from the...dinosaurs every day. They made me happy. Grad school can provide plenty of negativity, so I volunteered at...wonderfully supportive mentor and graduate office. I cannot stress how important they were to my success as...
  5. Data Freedom: The Expansion of Data Sharing in Research Publications

    Type
    Blog Post
    Published
    Aug. 5, 2014, 6:51 p.m.
    ... data easily available, organized in a form that can be understood by others, balanced against how often...rarely preserve “raw” data of any sort in a form that can be parsed by someone other than the actual author...Addgene helps with DNA reagents, these resources can offload the burden of data storage and distribution... storing data in a sharable form is indeed a significant effort. Our standards of data recording are highly...Research Institute at Mount Sinai Hospital, Toronto, Canada where he studies protein-serine/threonine kinases...
  6. Beginner's Guide to Viral Vectors

    Type
    Blog Post
    Published
    June 2, 2017, 2:30 p.m.
    ...You can use viral vectors for many experimental purposes. To help you make sense of all the viral vector...
  7. Meet the New Addgene Board Members!

    Type
    Blog Post
    Published
    April 28, 2020, 1:14 p.m.
    ...age, I was fascinated by the impact that medicines can have on human health. As a teenager in high school...from for profit organizations are less common, they can be very impactful. At Novartis, Stegmeier deposited...high-resolution tracking of more than 1 million cancer cells under drug treatment.” Stegmeier especially...
  8. New and Upcoming Viral Vectors - December 2019

    Type
    Blog Post
    Published
    Dec. 19, 2019, 2:40 p.m.
    ...AAV we have released in the last few months. You can also browse our entire AAV inventory. Our new AAVs...in target cells. While the various AAV serotypes can be used to achieve different patterns of expression...
  9. The Strength of Story Telling

    Type
    Blog Post
    Published
    Dec. 19, 2017, 2 p.m.
    ...story short, telling a good story is something that can be learned, and will serve you well in your career... people enjoy and engage with and what parts you can leave out. Start viewing your work in the form of...other options. Choose something with emotional significance that is likely to be memorable. Work out what...
  10. The Golden Stopwatch Award: Recognizing Facilitators of Research

    Type
    Blog Post
    Published
    Sept. 5, 2019, 1:06 p.m.
    ... themselves from undue liability. Before Addgene can begin distributing a material, a deposit agreement...deposits with and/or requests materials from Addgene can qualify. We also reward improvement against one’s...Dana-Farber Cancer Institute  Fred Hutchinson Cancer Research Center Memorial Sloan-Kettering Cancer Center...
  11. Single-cell tracking of lineage and identity with CellTag

    Type
    Blog Post
    Published
    May 9, 2019, 1:15 p.m.
    ...or the clonal evolution of cancer. If you’re looking to use CellTag, you can find the CellTag libraries...progenitors (iEPs), a self-renewing cell type that can differentiate into hepatic or intestinal cell types...
  12. Year of the Camelid: Antibody Style

    Type
    Blog Post
    Published
    May 9, 2024, 1:15 p.m.
    ...for diverse applications. For example, RANbodies can be used as an alternative to conventional primary...target antigens in living cells or tissues. sdAbs can also be used to manipulate cellular functions, like...sdAbs have become appealing candidates for the detection of different cancers (Jin, et al. 2023).  So where...
  13. New Norepinephrine Indicators: nLightG and nLightR

    Type
    Blog Post
    Published
    Dec. 12, 2023, 2:15 p.m.
    ...drugs targeting these receptors cannot be studied using GRABNE. They can, however, be studied with the ... antagonist. This is important because alpha2-AR can provide inhibitory feedback in response to norepinephrine...GRABNE, with both nLightG and nLightR showing significantly increased selectivity for norepinephrine over...
  14. Hot Plasmids and Viral Preps - July 2021

    Type
    Blog Post
    Published
    July 27, 2021, 1:15 p.m.
    ...for enrichment of successfully targeted cells that can be used to generate organoid cultures with a modification...identified, functions at temperatures up to 43 °C and can be used for genome editing in moderate thermophiles...
  15. Plasmids 101: A Brief History of Plasmids and an Improved eBook!

    Type
    Blog Post
    Published
    Oct. 29, 2015, 2:30 p.m.
    ...research, they are now seen as an ubiquitous tool that can be diversely applied to many different experiments...Ed.) eBook And now for some exciting news... You can now download the newest version of Addgene's Plasmids...
  16. Extracurricular Activities for a Strong Science Career Path

    Type
    Blog Post
    Published
    Jan. 21, 2014, 3:08 p.m.
    ...to engage in extracurricular activities (EA). EAs can: Introduce new perspectives in science and engineering...the big picture of the project. For example, how can future regulations impact your work? What design ...
  17. Antibodies 101 Series on TikTok

    Type
    Blog Post
    Published
    March 19, 2024, 1:15 p.m.
    ...shared on our @addgene Instagram account, or you can watch the full animation on our YouTube channel.  ...
Showing: 741 - 760 of 898 results