We narrowed to 789 results for: mpl
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TypeBlog PostPublishedJune 22, 2021, 1:15 p.m....used live virus (Cele et al., 2021). “We weren't completely shocked [with these results] because we were ...
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A New Optogenetic Tool Based on AraC Controls Gene Expression with Blue Light
TypeBlog PostPublishedJune 17, 2021, 1:17 p.m.... compared to the original AraC system, BLADE is simply more precise. “We show that you have less heterogeneity... -
Another Pathway into Cells: iTOP
TypeBlog PostPublishedJune 23, 2015, 8:37 p.m....instead of supplying a DNA construct, they could simply induce cells to take up protein directly? It’s ... -
Viral Vectors 101: Inverted Terminal Repeats
TypeBlog PostPublishedOct. 19, 2023, 1:15 p.m....and transgene expression (Zhou et al. 2017). For example, mutations in the RBE site reduce binding with ... -
Visualizing Genomic Loci with CRISPR-Sirius
TypeBlog PostPublishedApril 18, 2019, 12:53 p.m....al. “CRISPR-Sirius: RNA scaffolds for signal amplification in genome imaging.” Nature Methods 15 (2018)... -
The Crispr Babies Saga Shows the Need for Action, Not More Delays
TypeBlog PostPublishedDec. 20, 2018, 1:15 p.m....techniques are continually being refined; it is completely plausible that scientists will eventually have... -
5 Great Apps for Lab Life
TypeBlog PostPublishedSept. 22, 2016, 2:30 p.m....pocket. 5. +AMINO- by iGreenEarth AMINO is a very simple app that packs important biological information... -
"Build Your Plasmid": The Game - Play to Teach
TypeBlog PostPublishedJuly 17, 2018, 12:23 p.m....playing a card game called “Magic”. There were complicated rules that governed how this game was played.... -
Summer SciComm Series: A PhD in Science Communication
TypeBlog PostPublishedAug. 23, 2022, 1:15 p.m....adeolitis” – received the best ratings overall, simply because none of the participants had preconceived... -
DAP arrays for multiplex gene editing
TypeBlog PostPublishedJuly 7, 2022, 1:15 p.m...., we provide detailed manual and online design examples of using Addgene plasmids hCtRNA_FT (#186715) ... -
Scientists Map the SARS-CoV-2-Human Interaction Network
TypeBlog PostPublishedApril 9, 2020, 1:15 p.m.... SARS-CoV-2 interacts with human proteins. For example, we used HEK293T cells in our first study, but ... -
Synthetic Photobiology: Optogenetics for E. coli
TypeBlog PostPublishedSept. 8, 2015, 2:30 p.m....consistent, and controllable pulses of light. Complicated patterns of light intensity and wavelength can... -
Viral Vectors 101: Viral Vector Elements
TypeBlog PostPublishedJuly 25, 2023, 1 p.m....with each other to allow DNA synthesis of the complementary strand to yield dsDNA. Unlike LTRs, ITRs are... -
A Novice's Perspective on Neuroscience - SfN2017
TypeBlog PostPublishedDec. 15, 2017, 2:07 p.m....While walking around the exhibition area, I got a sampling of the broad variety of tools in neuroscience ... -
Cancer, Inflammation and Immunity - Harnessing the Body’s Defenses to Fight Cancer
TypeBlog PostPublishedJuly 6, 2017, 1:59 p.m....state by inducing immunosuppressive measures, for example the upregulation of the immunosuppressive cell ... -
Opto-Nanobodies: Using Light to Manipulate Cell Signaling and Protein Purification
TypeBlog PostPublishedNov. 19, 2019, 2:08 p.m....levers to pull to control signaling pathways. For example, if the OptoNB could bind and block a receptor ... -
Choosing a CRISPR Nuclease: Site Accessibility, Specificity, and Sensitivity
TypeBlog PostPublishedNov. 5, 2019, 1:28 p.m....better suit specific experimental approaches. One example is CasX, characterized by the Oakes and Doudna ... -
Hot Plasmids - May 2022
TypeBlog PostPublishedMay 26, 2022, 1:15 p.m....mice and nonhuman primates (for AAV.CAP-B10, for example). Given that the liver is an immunologically active... -
Fluorescent CRISPR Reporters: SRIRACCHA and GEmCherry2
TypeBlog PostPublishedMay 26, 2020, 1:15 p.m....allows for easy screening of different gRNAs by simply changing the gRNA used when transfecting your cells... -
Expanding the Targeting Scope and Editing Efficiency of Adenine Base Editors
TypeBlog PostPublishedMarch 17, 2020, 1:32 p.m....phage mutation rate Phage infection results in a complete ABE protein. If the phage delivers an active variant...