We narrowed to 855 results for: PLE;

1. Top 10 Open Science Developments of 2013

   Type

   Blog Post

   Published

   Dec. 19, 2013, 3:46 p.m.

   ... Year, let's make a toast to open science. And, please, share your favorite OA developments of the past...

2. A new platform for fast functional characterization of potentially cancerous mutations

   Type

   Blog Post

   Published

   May 7, 2019, 12:39 p.m.

   ...scientists understand how a given gene is involved in a complex pathway. Some of the most heavily-studied genes...

3. CRISPR Protocol for Genomic Deletions in Mammalian Cell Lines [Video]

   Type

   Blog Post

   Published

   Feb. 18, 2015, 3:09 p.m.

   ... (DSB) approach at a variety of loci. We were pleasantly surprised by the efficiency of the method. One...

4. Three Tips to Organize Your Lab Notebooks in the New Year

   Type

   Blog Post

   Published

   Jan. 2, 2014, 3:44 p.m.

   ...you identify when others have added or removed samples. Once you've taken some time to get organized, ...

5. 2023 and 2024: Reflections and Looking Ahead

   Type

   Blog Post

   Published

   Jan. 23, 2024, 2:15 p.m.

   ... our export license application service, we’re pleased to announce that we are now able to ship rabies...

6. Scientific Sharing in the Time of COVID-19: Databases and Resources

   Type

   Blog Post

   Published

   May 12, 2020, 1:15 p.m.

   ... investigators the agility to rapidly initiate complex research projects that they would otherwise not...

7. Same Addgene, New Look - Why We Redesigned Our Homepage & Mascot

   Type

   Blog Post

   Published

   Dec. 5, 2019, 1:49 p.m.

   ...next science challenge. If you have any feedback, please contact us and let us know how you’re feeling.  ...

8. A Better Way to Get Customer Support: The Help Center

   Type

   Blog Post

   Published

   Dec. 10, 2015, 3:30 p.m.

   ... time to be waiting on hold, let alone waiting multiple days for a reply to an email. You need answers...

9. Future of Research Conference - Remarkable Opening Session

   Type

   Blog Post

   Published

   Oct. 7, 2014, 3 p.m.

   ...Richard Roberts, CSO of New England Biolabs, gave examples of how you don’t have to be in academia to make...

10. 9 Tips to Achieve Success in Academia

    Type

    Blog Post

    Published

    April 1, 2014, 5:33 p.m.

    ...multidisciplinary one.” Cepko strongly emphasizes that people should “follow their passions, be happy, and match...

11. Lentiviral CRISPR Libraries Enable Genome-Scale, Knockout Screening

    Type

    Blog Post

    Published

    Feb. 20, 2014, 4:57 p.m.

    ...their demonstrated application offer proof-of-principle that CRISPR-Cas9 can be used to target any sequence...

12. CASTing Off for New Shores in Human Genome Editing

    Type

    Blog Post

    Published

    June 10, 2025, 1:15 p.m.

    ...2017). Type I CAST systems rely on the Cascade complex minus its nuclease component, Cas3, while Type ...

13. Chemogenetics vs. Optogenetics: Which Method Should I Choose?

    Type

    Blog Post

    Published

    June 11, 2020, 1:34 p.m.

    ...increasingly faster kinetics. The opsin ChETA, for example, is a ChR2 opsin mutated to have faster off kinetics...

14. Genetically-encoded Sparse Cell Labeling - A SPARC of Innovation

    Type

    Blog Post

    Published

    May 21, 2020, 1:15 p.m.

    ...Until recently, there were no completely genetic tools that would allow researchers to label just a fraction...

15. Early Career Researcher Toolbox: Free Tools for Making Scientific Graphics

    Type

    Blog Post

    Published

    June 11, 2019, 1:16 p.m.

    ...your search to particular types of images. For example, by selecting “Tools” and then clicking the “Usage...

16. Bringing Sustainable Practices to the Lab: Recycling

    Type

    Blog Post

    Published

    Feb. 14, 2019, 2:35 p.m.

    ...packaging (no coated tissue culture plates, for example). Check the link for more details on what they ...

17. CRISPR 101: Cas9 Nickase Design and Homology Directed Repair

    Type

    Blog Post

    Published

    March 15, 2018, 12:59 p.m.

    ...Overview of Cas9 nickase We’ll use SpCas9 nickases as examples for this post. The D10A mutation inactivates the...

18. Plasmids 101: Walkthrough of Addgene’s Snapgene-Powered Quality Control Process

    Type

    Blog Post

    Published

    Feb. 1, 2018, 3:07 p.m.

    ...Snapgene desktop software allows us to quickly align multiple sequences at the same time. This means we can ...

19. Using Ultrasound to Image Bacteria in vivo: Acoustic Reporter Genes

    Type

    Blog Post

    Published

    June 19, 2018, 1:38 p.m.

    ...arg2 ultrasound signals. This also means that multiplexing is possible if bacteria are sequentially exposed...

20. Some Like it Hot: Thermostable GeoCas9

    Type

    Blog Post

    Published

    Sept. 14, 2017, 12:40 p.m.

    ...editing. See figure 4 in Harrington et al for more examples of GeoCas9’s editing activity in HEK293’s. GeoCas9...