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We narrowed to 790 results for: Cre

Showing: 411 - 420 of 790 results

  1. What's New in CRISPR - December 2019

    Type
    Blog Post
    Published
    Dec. 17, 2019, 2:37 p.m.
    ... developed SECURE cytosine base editors, which decrease the rate of off-target genome edits compared to...adenine and cytosine editor). Target-ACE exhibits increased editing efficiency of a target site compared to...advantages like reduced off-target activity and decreased immune response to Cas9. Recently, Baisong Lu’...

  2. Top 10 Open Science Developments of 2013

    Type
    Blog Post
    Published
    Dec. 19, 2013, 3:46 p.m.
    ...million in annual R&D expenditures to support increased public access to the results of federally-funded...recommend Eric Lander's intro to biology course "The Secret of Life." 10)     And, last but not least (certainly...know your favorite ways to share science. Image credit: Judy Breck, via flickr  ...

  3. From our Table to Yours: An Inside Look at Lunch at Addgene

    Type
    Blog Post
    Published
    Nov. 27, 2013, 2:54 p.m.
    ... we created one long lunch table and we eat together Harry Potter-style.The shared lunches create a culture...or says something about my cooking.   This is a creative (and delicious) team building activity that is...

  4. Seeing Red: Simple GFP Photoconversion

    Type
    Blog Post
    Published
    Aug. 4, 2015, 2:30 p.m.
    ...characterized, it turns out this protein has a few more secrets - during a collaboration, members of Maureen Hanson...necessary to observe a signal. Red signal intensity increases with GFP concentration and saturates around 30...likely to be most useful for labs that already have created a transgenic GFP-containing organism,” says Hanson...

  5. IDP and your PI: A Roadmap for Career Planning and Personal Development

    Type
    Blog Post
    Published
    July 21, 2015, 2:30 p.m.
    ...holds yearly planning meetings with each trainee to create a supportive, growth-oriented lab culture. The ...perfectionists,” and we don’t often give ourselves credit for what we have accomplished. Starting with a ...meetings make the lab run more smoothly. With a concrete plan in hand, trainees are motivated to complete...

  6. Easing the Protein Purification Process with pCri

    Type
    Blog Post
    Published
    June 19, 2015, 3:08 p.m.
    ...that your protein might not fold well, you should screen a few different vectors to see which gives you ...subtilis and the yeast Pichia pastoris. The improved secretory capacities of these microbes make them useful ...peptide (SP) that routes the protein through the secretory pathway to improve folding and disulfide bond ...

  7. Inside Addgene's 10 Year Anniversary Gala

    Type
    Blog Post
    Published
    July 3, 2014, 3:48 p.m.
    ... today. Although I wish I could take all of the credit, the success of the company is attributed to the... of an interactive game that Addgene employees created and designed for the Hall of Human Life at the ...Addgene means to them. Ken mentioned Addgene’s incredible growth and our determination to keep materials...

  8. Three Tips to Organize Your Lab Notebooks in the New Year

    Type
    Blog Post
    Published
    Jan. 2, 2014, 3:44 p.m.
    ...Use software such as Evernote or Google Tasks to create lists of your upcoming tasks, set deadlines, and... computer or smartphone. Evernote allows you to create notes directly from webpage clippings, photographs...attachments. Organize your notes into notebooks, create checklists that link to other notes, and use the...

  9. Supporting Rare Disease Research with BeHeard 2017

    Type
    Blog Post
    Published
    July 20, 2017, 2:30 p.m.
    ... interacting partners and perform whole animal screens for small molecules that block the neurodegenerative...their expression in specific cells. With a more concrete understanding of the molecular biology behind ...and pathways to target in future small molecule screens. He plans to work with a partner at IRCCS Besta...

  10. Mapping the 4D nucleome with CRISPR/Cas9

    Type
    Blog Post
    Published
    Aug. 11, 2015, 2:30 p.m.
    ...response to the cell cycle or other stimuli.   To create a colorful Cas9 toolbox, Ma et al. turned to SpCas9...was fused to a different fluorescent protein to create three colors. The specificity of these orthologs...nucleome a specific priority, as researchers work to increase our understanding of chromatin organization. This...
Showing: 411 - 420 of 790 results