We narrowed to 904 results for: CAN

...describe how a better understanding of Cas9 biophysics can help enhance HDR. CRISPR 101: Ribonucleoprotein (...

...serotypes. Not sure what to request? Addgene's Data Hub can help, with over 100 user-submitted viral vector reports...pAAV-EF1α-F-FLEX-mNaChBac-T2A-tdTomato AAV8 Molecular tool Massimo Scanziani New viral prep pAAV_hSyn1-SIO-stGtACR2-FusionRed...

...Running4Rare are paired with patient partners so that they can help tell their stories. I was paired with a six-...named AJ Gonzales who suffers from Fibrodysplasia ossificans progressiva (AKA FOP). This terrible disease ...always work as efficiently in humans. This is why we cannot stop searching for novel solutions to treat rare...

...challenges of creating biological circuits, and I can only say this science is really, really hard. That...

...New Yorker’s “Comma Queen” shows how punctuation can be wildly funny as well as financially critical. ...and jobs. At Science, which is published by the American Association for the Advancement of Science (AAAS...Senior Editor at Science magazine, published by the American Association for the Advancement of Science. She...

... be unable to get into the target cells and this can be detected via loss of luminescence.     B.1.351...

... CD9 (a known marker molecule for microvesicles) can further improve AAV yields as CD9 is thought to enhance...

...follows a similar path to base transition editing, we can expect several generations of optimization before...standard tools. Additionally, aspiring genetic editors can now compare the advantages of base editing and prime...processes that would cause DSBs, and its inclusion significantly reduced indels generated by CGBEs. What's next...

...reagents are all ways in which the scientific community can support repositories. Repositories are essential ...this virus. One such example is cell lines. The American Type Culture Collection (ATCC) is a private, nonprofit...

...solving a community’s issue without involving them can do more harm than good. Check out this webinar for...

... that many more experiments are needed before we can consider clinical applications for germline editing...biologists and non-biologists alike. Given the public significance of this research, we have the obligation to ...

...with postdocs at other institutions to see if we can similarly convince them to go ahead with raises. ...level, in the case of some public institutions) to cancel plans to raise salaries. What are institutions ...expecting a salary increase have had that increase cancelled. Rounding out the remainder, 2% of postdocs who... are continuing with their plans, and 17 have cancelled their plans. 2 of those raising - the University...Illinois and the University of Michigan - initially cancelled their plans, but have since reversed their position...announced that they were reversing their plans to cancel raises). A further 9 institutions, whose plans ... In addition, PIs at some of the institutions cancelling plans are going ahead with raises anyway, including...

...been a privilege to find and share what stories we can, and to hear the stories others have to tell.  "Also...

...the Future or Research Symposium Boston 2015 you can register here or live stream the event on October...

... focused group of participants. More information can be found at http://futureofresearch.org/advocating-for-science-boston...and keynote by former congressman and CEO of the American Association for the Advancement of Science, Rush...solutions. The event also culminated in a joint American Society for Biochemistry and Molecular Biology...keynote address by former congressman and CEO of the American Association for the Advancement of Science, Rush...

... on a prokaryotic transcript is non-specific and can be added to any accessible 3' end. The presence of...

...only scratched the surface of modifications that can be made to Cas9. It is a pleasant surprise that selecting...

...real value here is seeing them all in one place. Can we address problems in scientific publishing without...posits the way science is being done has changed significantly over the last decade. He describes the detection...

... from just one lab, which limits how broadly one can interpret our analysis of COVID-19’s effect on scientific...months, pausing or terminating employment for a significant fraction of the workforce. Wet lab scientists...exponential decay model, with dips during weekends and significant holidays. Figure 4: Plasmid request trajectories...or labs placing orders for paper x on date t. We cannot use individual plasmid orders, because when a PI...Institute and Harvard University. Max Shen is a Ph.D. candidate at MIT. His research uses applied machine learning...

... from reaching their targets. The AAV9 serotype can breach the BBB following injection into the bloodstream...PHP.B to reach the CNS; yet LY6A is an unlikely candidate. It was discovered as an antigen upregulated on...this stretch of DNA, Ly6a seemed the most likely candidate due to its strong linkage to the PHP.B phenotype...variants could unintentionally limit the utility of candidate capsids.  Are you interested in using AAV-PHP....