We narrowed to 904 results for: CAN

...disease is caused by a mutation in a single gene, it can potentially be treated by correcting the mutation.... However, many diseases require techniques that can deliver gene therapies directly to the cells that... tools such as nanoparticles. These technologies can have serious adverse effects, and their immunogenic... human population. These pre-existing antibodies can interfere with virus-cell interactions and seriously...the immune system – patients’ own immune systems can develop antibodies that neutralize the AAV vectors...disease, and HIV. A notable landmark study showed significant clinical efficacy against a form of blindness... of LCA and mutations in RPE65 (n=3), showed significant improvements in vision over a period of 1 to ...

...microelectronic fibers made from thermoplastic polymers that can work with all the bells and whistles. The fibers ... molecules.   Fun fact: A 1 cm block of polymer can generate many meters of fibers!     Fig...its associated fibers across multiple channels and can also record tissue temperature proximal to the implanted...a rechargeable battery, is relatively small, and can be detached easily whenever necessary. This is all...

...-inducible Proteins (FLiPs) Fluorescent proteins can be applied in a long list of creative ways. In her...photoswitchable fluorescent proteins to create enzymes that can be turned on and off with light.  Xin hypothesized...presented her work at the 2017 Winter qBio Meeting. You can learn more about Xin’s work with photoswitchable ...expression of GFP from the lac operon. GFP expression can then be used to determine the amount of HMO originally...Zhou and Fatima Enam. There were many excellent applicants but Xin and Fatima stood out for their creativity...

...record yourself. You can watch yourself to critique and figure out what to improve. You can share it with others...charge before others do”. Candidates who have “started something” which they can share on their resumes ...There are many different kinds of grants that you can apply for. If you are in a lab, your PI is likely...to work-from-home and just now realizing that we can’t bide our time and wait for it to be over to work...roles but for almost every position, we look for candidates that have demonstrated initiative. In fact, hear...have a definite advantage in our process. We see candidates who have done the following types of things: ...relationships when you are more desperate or needy so you can’t wait until you imminently need a job. Start now....

...this can lead to wasted time or retractions. Using a catalog number for identifying a reagent can be helpful...specific Addgene ID # listed in a publication, you can quickly pull up the associated plasmid page on the...87155 ; RRID:Addgene_87155).” So when citing, you can copy and paste the text attributing the PI who generated...

...protein are overexpressed in cells, microtubule growth can be switched off with blue light which causes LOV2...recently developed “Riboglow,” a set of tools that can be used to visualize RNA localization in mammalian... tags using the same number of fluorophores. You can find plasmids containing the cobalamin binding riboswitches...APOBEC1. Finally, they show that the ACE reporter can also quantify Cas9 cleavage, thus exhibiting its ...This paper demonstrated that the migration of a cancer cell line equipped with photodissociable EB1 could...

...what appears to be a funky old garage, but looks can be deceiving. Step into this building and you will...volunteers. Transforming citizens into scientists Anyone can become a member of BosLab and previous laboratory...environment, and openly publish protocols so that anyone can engineer yeast to do similar things. The focus is... To learn more about what we’re up to or how you can help BosLab, visit our website and follow us on twitter...

...calcium sensors, which are available at Addgene, can be used for ratiometric in vivo imaging. Griesbeck...on" in the presence of calcium. This color change can be observed under a microscope using commercially... beginners Griesbeck says his calcium indicators can be used in mouse, Drosophila, C. elegans, and zebrafish...and his colleagues took to optimize sensitivities can now be applied to dozens of other published FRET-...

...recommends to seek out advice from seasoned PIs who can offer support. “It is an exciting and emotional time... not rush when growing your lab. “One bad choice can be counter-productive." He also emphasizes the point... at about 65,000 messages and dealing with email can be half of my day sometimes.” He points out that ... to companies.” Take home message Starting a lab can be a challenging process. Each PI emphasizes the ... team so getting everyone talking to each other cannot be undervalued.” Connie Cepko points out the limited...

...a student or postdoc ends up in a lab where they can learn the plus skills needed to succeed on the career...disseminating career training approaches in a way that can be implemented widely in the community.  Talk alone...scheduled for March 4th from 2:30-4:00 pm ET.  You can learn more about the report's recommendations and...