Multifunctional Neural Fibers: Modulation from Gut to Brain
Type
Blog Post
Published
Aug. 31, 2023, 1 p.m.
...s41587-023-01833-5
Resources on Addgene.org
Optogenetics guide
Chemogenetics guide
BRAIN initiative plasmid... on the Addgene blog
Plasmid tools for microbiome studies
Channel rhodopsins for optogenetics
Viral Vectors...electric stimulation, drug administration, and optogenetics. Enter neural fibers!
The neural fiber tool...features enable the fibers to emit light for optogenetic purposes, measure temperature, study electrophysiology...molecules.
Fun fact: A 1 cm block of polymer can generate many meters of fibers!
Fig. 1 - ...the labs looked at previous implementation of optogenetic tools, calcium sensors, and other common neuroscience...for gut implantation. The fibers they ended up generating were 10-15 times more flexible than the brain...