We narrowed to 214 results for: gnal
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TypeBlog PostPublishedDec. 30, 2015, 3:30 p.m....already been used for includes work probing mTOR signaling in cancer cells, deciphering the mechanism of ...
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CRISPR-Cas14: a family of small DNA-targeting enzymes enabling high-fidelity SNP genotyping
TypeBlog PostPublishedNov. 29, 2018, 1:53 p.m....fluorescent probes of dsDNA and RNA in trans. Fluorescent signal indicates the presence of this viral sequence in... -
Top Requested AAV of 2017: pmSyn1-EBFP-CRE
TypeBlog PostPublishedJan. 17, 2018, 2:57 p.m.... your injection site. This would help you map signalling between different regions of the brain. There... -
Supporting Rare Disease Research with BeHeard 2017
TypeBlog PostPublishedJuly 20, 2017, 2:30 p.m.... coworkers to test inhibitors of a variety of signaling pathways for their effects on the disease. This... -
Celebrating Outstanding CRISPR/Cas9 Achievements at the Dr. Paul Janssen Award Dinner
TypeBlog PostPublishedSept. 15, 2014, 6:05 p.m....generate mice with genes knocked out in the insulin signaling cascades in only 4 months compared to a year or... -
Sensing Neuronal Dopamine
TypeBlog PostPublishedJuly 30, 2019, 12:59 p.m.... neurons in live mice Report modulation of DA signaling during learning and reward consumption in live... -
Zebrafish as a Model for Behavior: Swimming into the Optogenetic Spotlight
TypeBlog PostPublishedJuly 16, 2019, 12:59 p.m....threshold, it becomes depolarized and will fire a signal. The non-specific cation channel ChR2 and the calcium... -
Antibodies 101: Avoiding the Mouse on Mouse Mess in IHC
TypeBlog PostPublishedSept. 21, 2023, 1:15 p.m....antibodies can be expensive and may not provide enough signal to visualize low-abundance targets. Pre-formed... -
Bright Monomeric Fluorescent Proteins: mNeonGreen, mTFP1, and mWasabi
TypeBlog PostPublishedApril 25, 2019, 3:01 p.m....This combination results in a 2.6-fold increase in signal relative to mCerulean imaged with a standard CFP... -
A New Optogenetic Tool Based on AraC Controls Gene Expression with Blue Light
TypeBlog PostPublishedJune 17, 2021, 1:17 p.m..... While none of the constructs gave as strong a signal as with the wild-type AraC, it still reached the... -
Viral Vectors 101: Parts of the AAV Transfer Plasmid
TypeBlog PostPublishedAug. 11, 2020, 1:15 p.m....final ITR. polyA The polyadenylation or polyA signal aids in the nuclear export of RNA and RNA translation... -
In Vivo Biotinylation of Bacterial Fusion Proteins
TypeBlog PostPublishedJan. 25, 2018, 2:09 p.m....Institute and is particularly interested in cell signaling. Additional Resources on the Addgene Blog ... -
Fluorescent Biosensors for Measuring Autophagic Flux
TypeBlog PostPublishedJan. 22, 2019, 2:41 p.m....wavelength, Keima emits at 620 nm. The ratio of signal strength excited at 586 nm to 440 nm serves as ... -
10 Great Guest Posts We're Thankful For
TypeBlog PostPublishedNov. 18, 2016, 3 p.m.... single cell, and localization of a fluorescent signal to your target gene. Read this post to find out... -
Even more elegant: Single injection CRISPR/Cas9 in C. elegans
TypeBlog PostPublishedJuly 7, 2015, 3:36 p.m....engineering methods for C. elegans were released, signaling a new era in C. elegans research. Homology directed... -
Fluorescent Protein Travel Awards - FLiPs and Fluorescent Protein Biosensors
TypeBlog PostPublishedJuly 27, 2017, 1:11 p.m....work with photoswitchable components of the ERK signaling pathway in our recent blog post. Fatima Enam: ... -
New and Upcoming Viral Vectors - September 2019
TypeBlog PostPublishedSept. 12, 2019, 1 p.m.... peak fluorescence) and is useful for imaging signaling activity in large populations of densely-labeled... -
Fluorescent Protein Travel Awards - Protein Variants, a Serotonin Sensor, and an Artificial Leaf Replica System
TypeBlog PostPublishedJune 4, 2019, 1:02 p.m....fluorescent proteins will be diluted out and the signal will diminish. Once the system is validated, Bernach... -
Revamp Your Lab Meetings With Creative Virtual Collaboration
TypeBlog PostPublishedFeb. 9, 2021, 2:15 p.m.... of meeting, someone could raise their hands or signal the approach of a brain break, where everyone stands... -
With Our New Viral Service, We're Taking CRISPR Further!
TypeBlog PostPublishedDec. 6, 2016, 3:30 p.m....gRNAs allow you to target these widely studied signalling pathways. Find Validated gRNAs to use with your...